Pharmacotherapy for weight loss: the cardiovascular effects of the old and new agents
dc.contributor.author | Walter, C. P. | en_US |
dc.contributor.author | Bleske, B. E. | en_US |
dc.contributor.author | Dorsch, M. P. | en_US |
dc.date.accessioned | 2014-09-03T16:51:35Z | |
dc.date.available | WITHHELD_14_MONTHS | en_US |
dc.date.available | 2014-09-03T16:51:35Z | |
dc.date.issued | 2014-10 | en_US |
dc.identifier.citation | Walter, C. P.; Bleske, B. E.; Dorsch, M. P. (2014). "Pharmacotherapy for weight loss: the cardiovascular effects of the old and new agents." Journal of Clinical Pharmacy and Therapeutics 39(5): 475-484. | en_US |
dc.identifier.issn | 0269-4727 | en_US |
dc.identifier.issn | 1365-2710 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/108287 | |
dc.publisher | Wiley Periodicals, Inc. | en_US |
dc.subject.other | Lorcaserin | en_US |
dc.subject.other | Obesity | en_US |
dc.subject.other | Phentermine/Topiramate | en_US |
dc.subject.other | Weight Loss | en_US |
dc.title | Pharmacotherapy for weight loss: the cardiovascular effects of the old and new agents | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/108287/1/jcpt12177.pdf | |
dc.identifier.doi | 10.1111/jcpt.12177 | en_US |
dc.identifier.source | Journal of Clinical Pharmacy and Therapeutics | en_US |
dc.identifier.citedreference | Product information. (BELVIQ) Lorcaserin. Zofingen, Switzerland: 2012. | en_US |
dc.identifier.citedreference | Pasqualetti M, Ori M, Castagna M, Marazziti D, Cassano GB, Nardi I. Distribution and cellular localization of the serotonin type 2C receptor messenger RNA in human brain. Neuroscience, 1999; 92: 601 – 611. | en_US |
dc.identifier.citedreference | Huang X, Setola V, Yadav P. Parallel functional activity profiling reveals valvulopathogens are potent 5‐hydroxytryptamine2B receptor agonists: implications for drug safety assessment. Mol Pharmacol, 2009; 76: 710 – 722. doi: 10.1124/mol.109.058057. | en_US |
dc.identifier.citedreference | Smith SR, Weissman NJ, Anderson CM et al. Multicenter, placebo‐controlled trial of lorcaserin for weight management. N Engl J Med, 2010; 363: 245 – 256. doi: 10.1056/NEJMoa0909809. | en_US |
dc.identifier.citedreference | Fidler MC, Sanchez M, Raether B et al. A one‐year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial. J Clin Endocrinol Metab, 2011; 96: 3067 – 3077. doi: 10.1210/jc.2011‐1256. | en_US |
dc.identifier.citedreference | O'Neil PM, Smith SR, Weissman NJ et al. Randomized placebo‐controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM‐DM study. Obesity (Silver Spring), 2012; 20: 1426 – 1436. doi: 10.1038/oby.2012.66. | en_US |
dc.identifier.citedreference | FDA Briefing Document: NDA 22529. BELVIQ (lorcaserin). Arena Pharmaceuticals. | en_US |
dc.identifier.citedreference | Jaffré F, Bonnin P, Callebert J et al. Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic‐dependent cardiac hypertrophy. Circ Res, 2009; 104: 113 – 123. doi: 10.1161/CIRCRESAHA.108.180976. | en_US |
dc.identifier.citedreference | Gadde KM, Allison DB, Ryan DH et al. Effects of low‐dose, controlled‐release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo‐controlled, phase 3 trial. Lancet, 2011; 377: 1341 – 1352. doi: 10.1016/S0140‐6736(11)60205‐5. | en_US |
dc.identifier.citedreference | Allison DB, Gadde KM, Garvey WT et al. Controlled‐release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP). Obesity (Silver Spring), 2012; 20: 330 – 342. doi: 10.1038/oby.2011.330. | en_US |
dc.identifier.citedreference | Richard D, Ferland J, Lalonde J, Samson P, Deshaies Y. Influence of topiramate in the regulation of energy balance. Nutrition, 2000; 16: 961 – 966. | en_US |
dc.identifier.citedreference | Richard D, Picard F, Lemieux C, Lalonde J, Samson P, Deshaies Y. The effects of topiramate and sex hormones on energy balance of male and female rats. Int J Obes Relat Metab Disord, 2002; 26: 344 – 353. doi: 10.1038/sj.ijo.0801873. | en_US |
dc.identifier.citedreference | Picard F, Deshaies Y, Lalonde J, Samson P, Richard D. Topiramate reduces energy and fat gains in lean (Fa/?) and obese (fa/fa) Zucker rats. Obes Res, 2000; 8: 656 – 663. doi: 10.1038/oby.2000.84. | en_US |
dc.identifier.citedreference | FDA Briefing Document: NDA 022580. Qnexa (phentermine/topiramate). Vivus, Inc. | en_US |
dc.identifier.citedreference | Garvey W, Ryan D, Look M. metabolic benefits with controlled‐release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo‐controlled, phase 3 extension. Am J Clin Nutr, 2012; 95: 297 – 308. doi: 10.3945/ajcn.111.024927.INTRODUCTION. | en_US |
dc.identifier.citedreference | Greenway FL, Fujioka K, Plodkowski RA et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR‐I): a multicentre, randomised, double‐blind, placebo‐controlled, phase 3 trial. Lancet, 2010; 376: 595 – 605. doi: 10.1016/S0140‐6736(10)60888‐4. | en_US |
dc.identifier.citedreference | ClinicalTrials.gov: A service of the U.S. National Institutes of Health. Available at: http://www.clinicaltrials.gov/. (accessed April 2013) | en_US |
dc.identifier.citedreference | Flint A, Raben A, Astrup A, Holst J. Glucagon‐like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest, 1998; 101: 515 – 520. | en_US |
dc.identifier.citedreference | Naslund E, King N, Mansten S et al. Prandial subcutaneous injections of glucagon‐like peptide‐1 cause weight loss in obese human subjects. Br J Nutr, 2004; 91: 439 – 446. | en_US |
dc.identifier.citedreference | Angeli F, Shannon R. Incretin‐based therapies: can we achieve glycemic control and cardioprotection? J Endocrinol, 2014; 221: T17 – T30. | en_US |
dc.identifier.citedreference | Flegal K, Carroll M. Prevalence and trends in obesity among US adults, 1999–2000. JAMA, 2002; 288: 1723 – 1727. | en_US |
dc.identifier.citedreference | Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity in the United States, 2009–2010. NCHS Data Brief, 2012; 82: 1 – 8. | en_US |
dc.identifier.citedreference | Douketis JD, Sharma AM. Obesity and cardiovascular disease: pathogenic mechanisms and potential benefits of weight reduction. Semin Vasc Med, 2005; 5: 25 – 33. doi: 10.1055/s‐2005‐871739. | en_US |
dc.identifier.citedreference | Billington C, Epstein L, Goodwin N et al. Overweight, obesity, and health risk. Arch Intern Med, 2000; 160: 898 – 904. | en_US |
dc.identifier.citedreference | Wing R, Lang W, Wadden T. Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with Type 2 diabetes. Diabetes Care, 2011; 34: 1481 – 1486. doi: 10.2337/dc10‐2415. | en_US |
dc.identifier.citedreference | Black E, Holst C, Astrup A et al. Long‐term influences of body‐weight changes, independent of the attained weight, on risk of impaired glucose tolerance and Type 2 diabetes. Diabet Med, 2005; 22: 1199 – 1205. doi: 10.1111/j.1464‐5491.2005.01615.x. | en_US |
dc.identifier.citedreference | Goldstein D. Beneficial health effects of modest weight loss. Int J Obes Relat Metab Disord, 1992; 16: 397 – 415. | en_US |
dc.identifier.citedreference | Jensen MD, Ryan DH, Apovian CM et al. AHA/ACC/TOS guideline for the management of overweight and obesity in adults. Circulation, 2013. doi: 10.1161/01.cir.0000437739.71477.ee [Epub ahead of print]. | en_US |
dc.identifier.citedreference | Ioannides‐Demos LL, Proietto J, McNeil JJ. Pharmacotherapy for obesity. Drugs, 2005; 65: 1391 – 1418. | en_US |
dc.identifier.citedreference | NIH Publication. Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults.; 1998. Available at: http://hp2010.nhlbihin.net/oei_ss/download/pdf/CORESET1.pdf. (accessed 2 May 2013). | en_US |
dc.identifier.citedreference | Bray G. A concise review on the therapeutics of obesity. Nutrition, 2000; 16: 953 – 960. | en_US |
dc.identifier.citedreference | Weintraub M, Hasday J. A double‐blind clinical trial in weight control: use of fenfluramine and phentermine alone and in combination. Arch Intern Med, 1984; 144: 1143 – 1148. | en_US |
dc.identifier.citedreference | Guy‐Grand B, Crepaldi G, Vre P International trial of long‐term dexfenfluramine in obesity. Lancet, 1989; 2: 1142 – 1145. | en_US |
dc.identifier.citedreference | Connolly H, Crary J, McGoon M et al. Valvular heart disease associated with fenfluramine‐phentermine. N Engl J Med, 1997; 337: 581 – 588. | en_US |
dc.identifier.citedreference | Wee C, Phillips R, Aurigemma G et al. Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who underwent echocardiography before use of medication. Ann Intern Med, 1998; 129: 870 – 874. | en_US |
dc.identifier.citedreference | Sachdev M, Miller WC, Ryan T, Jollis JG. Effect of fenfluramine‐derivative diet pills on cardiac valves: a meta‐analysis of observational studies. Am Heart J, 2002; 144: 1065 – 1073. doi: 10.1067/mhj.2002.126733. | en_US |
dc.identifier.citedreference | Abenhaim L, Moride Y, Brenot F et al. Appetite‐suppressant drugs and the risk of primary pulmonary hypertension. N Engl J Med, 1996; 335: 609 – 616. doi: 10.1381/096089297765556114. | en_US |
dc.identifier.citedreference | Rich S, Rubin L. Anorexigens and pulmonary hypertension in the United States: results from the surveillance of North American pulmonary hypertension. Chest, 2000; 117: 870 – 874. | en_US |
dc.identifier.citedreference | Rothman RB, Baumann MH, Savage JE et al. Evidence for possible involvement of 5‐HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications. Circulation, 2000; 102: 2836 – 2841. | en_US |
dc.identifier.citedreference | Rothman R, Baumann M. Serotonergic drugs and valvular heart disease. Expert Opin Drug Saf, 2009; 8: 317 – 329. doi: 10.1517/14740330902931524.Serotonergic. | en_US |
dc.identifier.citedreference | Fitzgerald LW, Burn TC, Brown BS et al. Possible role of valvular serotonin 5‐HT(2B) receptors in the cardiopathy associated with fenfluramine. Mol Pharmacol, 2000; 57: 75 – 81. | en_US |
dc.identifier.citedreference | Eddahibi S, Adnot S. Anorexigen‐induced pulmonary hypertension and the serotonin (5‐HT) hypothesis: lessons for the future in pathogenesis. Respir Res, 2002; 3: 1 – 4. | en_US |
dc.identifier.citedreference | Dempsie Y, MacLean MR. Pulmonary hypertension: therapeutic targets within the serotonin system. Br J Pharmacol, 2008; 155: 455 – 462. doi: 10.1038/bjp.2008.241. | en_US |
dc.identifier.citedreference | Scheen A. Cardiovascular risk‐benefit profile of sibutramine. Am J Cardiovasc Drugs, 2010; 10: 321 – 334. | en_US |
dc.identifier.citedreference | Product information. Meridia (sibutramine). Abbott Laboratories. 2001. | en_US |
dc.identifier.citedreference | James W, Caterson I. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med, 2010; 363: 905 – 917. | en_US |
dc.identifier.citedreference | Haller CA, Jacob P, Benowitz NL. Pharmacology of ephedra alkaloids and caffeine after single‐dose dietary supplement use. Clin Pharmacol Ther. 2002; 71: 421 – 432. doi: 10.1067/mcp.2002.124523. | en_US |
dc.identifier.citedreference | Haller CA, Benowitz NL. Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med, 2000; 343: 1833 – 1838. doi: 10.1056/NEJM200012213432502. | en_US |
dc.identifier.citedreference | Shekelle P, Hardy M, Morton S et al. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta‐analysis. JAMA, 2003; 289: 1537 – 1545. | en_US |
dc.identifier.citedreference | Department of Health and Human Services. Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk; final rule. Fed Reg, 2004; 69: 6787 – 6854. | en_US |
dc.identifier.citedreference | White L, Gardner S, Marx M, Wang P, Estes M. Pharmacokinetics and cardiovascular effects of ma‐huang ( Ephedra sinica ) in normotensive adults. J Clin Pharmacol, 1997; 37: 116 – 122. | en_US |
dc.identifier.citedreference | Palamar J. How ephedrine escaped regulation in the United States: a historical review of misuse and associated policy. Health Policy, 2011; 99: 1 – 9. doi: 10.1016/j.healthpol.2010.07.007. | en_US |
dc.identifier.citedreference | Bailes J, Cantu R, Day A. The neurosurgeon in sport: awareness of the risks of heatstroke and dietary supplements. Neurosurgery, 2002; 51: 283 – 288. doi: 10.1227/01.NEU.0000020569.68133.12. | en_US |
dc.identifier.citedreference | Kernan WN, Viscoli CM, Brass LM et al. Phenylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med, 2000; 343: 1826 – 1832. doi: 10.1056/NEJM200012213432501. | en_US |
dc.identifier.citedreference | Padwal RS, Majumdar SR. Drug treatments for obesity: orlistat, sibutramine, and rimonabant. Lancet, 2007; 369: 71 – 77. doi: 10.1016/S0140‐6736(07)60033‐6. | en_US |
dc.identifier.citedreference | Rucker D, Padwal R, Li SK, Curioni C, Lau DCW. Long term pharmacotherapy for obesity and overweight: updated meta‐analysis. BMJ, 2007; 335: 1194 – 1199. doi: 10.1136/bmj.39385.413113.25. | en_US |
dc.identifier.citedreference | Padwal R, Li S, Lau D Long‐term pharmacotherapy for obesity and overweight. Cochrane Database Syst Rev, 2004; 3: CD004094. | en_US |
dc.identifier.citedreference | Torgeson J, Hauptman J, Boldrin M, Sjöström L. XENical in the prevention of diabetes in obese subjects (XENDOS) study. Diabetes Care, 2004; 27: 155 – 161. | en_US |
dc.identifier.citedreference | Haddock CK, Poston WSC, Dill PL, Foreyt JP, Ericsson M. Pharmacotherapy for obesity: a quantitative analysis of four decades of published randomized clinical trials. Int J Obes Relat Metab Disord, 2002; 26: 262 – 273. doi: 10.1038/sj.ijo.0801889. | en_US |
dc.identifier.citedreference | Charakida M, Finer N. Drug treatment of obesity in cardiovascular disease. Am J Cardiovasc Drugs, 2012; 12: 93 – 104. doi: 10.2165/11599000‐000000000‐00000. | en_US |
dc.identifier.citedreference | Kang JG, Park C‐Y. Anti‐obesity drugs: a review about their effects and safety. Diabetes Metab J, 2012; 36: 13 – 25. doi: 10.4093/dmj.2012.36.1.13. | en_US |
dc.identifier.citedreference | Miller K. Serotonin 5‐HT2c receptor agonists: potential for the treatment of obesity. Mol Interv, 2005; 5: 282 – 291. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.