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Pharmacotherapy for weight loss: the cardiovascular effects of the old and new agents

dc.contributor.authorWalter, C. P.en_US
dc.contributor.authorBleske, B. E.en_US
dc.contributor.authorDorsch, M. P.en_US
dc.date.accessioned2014-09-03T16:51:35Z
dc.date.availableWITHHELD_14_MONTHSen_US
dc.date.available2014-09-03T16:51:35Z
dc.date.issued2014-10en_US
dc.identifier.citationWalter, C. P.; Bleske, B. E.; Dorsch, M. P. (2014). "Pharmacotherapy for weight loss: the cardiovascular effects of the old and new agents." Journal of Clinical Pharmacy and Therapeutics 39(5): 475-484.en_US
dc.identifier.issn0269-4727en_US
dc.identifier.issn1365-2710en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/108287
dc.publisherWiley Periodicals, Inc.en_US
dc.subject.otherLorcaserinen_US
dc.subject.otherObesityen_US
dc.subject.otherPhentermine/Topiramateen_US
dc.subject.otherWeight Lossen_US
dc.titlePharmacotherapy for weight loss: the cardiovascular effects of the old and new agentsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/108287/1/jcpt12177.pdf
dc.identifier.doi10.1111/jcpt.12177en_US
dc.identifier.sourceJournal of Clinical Pharmacy and Therapeuticsen_US
dc.identifier.citedreferenceProduct information. (BELVIQ) Lorcaserin. Zofingen, Switzerland: 2012.en_US
dc.identifier.citedreferencePasqualetti M, Ori M, Castagna M, Marazziti D, Cassano GB, Nardi I. Distribution and cellular localization of the serotonin type 2C receptor messenger RNA in human brain. Neuroscience, 1999; 92: 601 – 611.en_US
dc.identifier.citedreferenceHuang X, Setola V, Yadav P. Parallel functional activity profiling reveals valvulopathogens are potent 5‐hydroxytryptamine2B receptor agonists: implications for drug safety assessment. Mol Pharmacol, 2009; 76: 710 – 722. doi: 10.1124/mol.109.058057.en_US
dc.identifier.citedreferenceSmith SR, Weissman NJ, Anderson CM et al. Multicenter, placebo‐controlled trial of lorcaserin for weight management. N Engl J Med, 2010; 363: 245 – 256. doi: 10.1056/NEJMoa0909809.en_US
dc.identifier.citedreferenceFidler MC, Sanchez M, Raether B et al. A one‐year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial. J Clin Endocrinol Metab, 2011; 96: 3067 – 3077. doi: 10.1210/jc.2011‐1256.en_US
dc.identifier.citedreferenceO'Neil PM, Smith SR, Weissman NJ et al. Randomized placebo‐controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM‐DM study. Obesity (Silver Spring), 2012; 20: 1426 – 1436. doi: 10.1038/oby.2012.66.en_US
dc.identifier.citedreferenceFDA Briefing Document: NDA 22529. BELVIQ (lorcaserin). Arena Pharmaceuticals.en_US
dc.identifier.citedreferenceJaffré F, Bonnin P, Callebert J et al. Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic‐dependent cardiac hypertrophy. Circ Res, 2009; 104: 113 – 123. doi: 10.1161/CIRCRESAHA.108.180976.en_US
dc.identifier.citedreferenceGadde KM, Allison DB, Ryan DH et al. Effects of low‐dose, controlled‐release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo‐controlled, phase 3 trial. Lancet, 2011; 377: 1341 – 1352. doi: 10.1016/S0140‐6736(11)60205‐5.en_US
dc.identifier.citedreferenceAllison DB, Gadde KM, Garvey WT et al. Controlled‐release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP). Obesity (Silver Spring), 2012; 20: 330 – 342. doi: 10.1038/oby.2011.330.en_US
dc.identifier.citedreferenceRichard D, Ferland J, Lalonde J, Samson P, Deshaies Y. Influence of topiramate in the regulation of energy balance. Nutrition, 2000; 16: 961 – 966.en_US
dc.identifier.citedreferenceRichard D, Picard F, Lemieux C, Lalonde J, Samson P, Deshaies Y. The effects of topiramate and sex hormones on energy balance of male and female rats. Int J Obes Relat Metab Disord, 2002; 26: 344 – 353. doi: 10.1038/sj.ijo.0801873.en_US
dc.identifier.citedreferencePicard F, Deshaies Y, Lalonde J, Samson P, Richard D. Topiramate reduces energy and fat gains in lean (Fa/?) and obese (fa/fa) Zucker rats. Obes Res, 2000; 8: 656 – 663. doi: 10.1038/oby.2000.84.en_US
dc.identifier.citedreferenceFDA Briefing Document: NDA 022580. Qnexa (phentermine/topiramate). Vivus, Inc.en_US
dc.identifier.citedreferenceGarvey W, Ryan D, Look M. metabolic benefits with controlled‐release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo‐controlled, phase 3 extension. Am J Clin Nutr, 2012; 95: 297 – 308. doi: 10.3945/ajcn.111.024927.INTRODUCTION.en_US
dc.identifier.citedreferenceGreenway FL, Fujioka K, Plodkowski RA et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR‐I): a multicentre, randomised, double‐blind, placebo‐controlled, phase 3 trial. Lancet, 2010; 376: 595 – 605. doi: 10.1016/S0140‐6736(10)60888‐4.en_US
dc.identifier.citedreferenceClinicalTrials.gov: A service of the U.S. National Institutes of Health. Available at: http://www.clinicaltrials.gov/. (accessed April 2013)en_US
dc.identifier.citedreferenceFlint A, Raben A, Astrup A, Holst J. Glucagon‐like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest, 1998; 101: 515 – 520.en_US
dc.identifier.citedreferenceNaslund E, King N, Mansten S et al. Prandial subcutaneous injections of glucagon‐like peptide‐1 cause weight loss in obese human subjects. Br J Nutr, 2004; 91: 439 – 446.en_US
dc.identifier.citedreferenceAngeli F, Shannon R. Incretin‐based therapies: can we achieve glycemic control and cardioprotection? J Endocrinol, 2014; 221: T17 – T30.en_US
dc.identifier.citedreferenceFlegal K, Carroll M. Prevalence and trends in obesity among US adults, 1999–2000. JAMA, 2002; 288: 1723 – 1727.en_US
dc.identifier.citedreferenceOgden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity in the United States, 2009–2010. NCHS Data Brief, 2012; 82: 1 – 8.en_US
dc.identifier.citedreferenceDouketis JD, Sharma AM. Obesity and cardiovascular disease: pathogenic mechanisms and potential benefits of weight reduction. Semin Vasc Med, 2005; 5: 25 – 33. doi: 10.1055/s‐2005‐871739.en_US
dc.identifier.citedreferenceBillington C, Epstein L, Goodwin N et al. Overweight, obesity, and health risk. Arch Intern Med, 2000; 160: 898 – 904.en_US
dc.identifier.citedreferenceWing R, Lang W, Wadden T. Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with Type 2 diabetes. Diabetes Care, 2011; 34: 1481 – 1486. doi: 10.2337/dc10‐2415.en_US
dc.identifier.citedreferenceBlack E, Holst C, Astrup A et al. Long‐term influences of body‐weight changes, independent of the attained weight, on risk of impaired glucose tolerance and Type 2 diabetes. Diabet Med, 2005; 22: 1199 – 1205. doi: 10.1111/j.1464‐5491.2005.01615.x.en_US
dc.identifier.citedreferenceGoldstein D. Beneficial health effects of modest weight loss. Int J Obes Relat Metab Disord, 1992; 16: 397 – 415.en_US
dc.identifier.citedreferenceJensen MD, Ryan DH, Apovian CM et al. AHA/ACC/TOS guideline for the management of overweight and obesity in adults. Circulation, 2013. doi: 10.1161/01.cir.0000437739.71477.ee [Epub ahead of print].en_US
dc.identifier.citedreferenceIoannides‐Demos LL, Proietto J, McNeil JJ. Pharmacotherapy for obesity. Drugs, 2005; 65: 1391 – 1418.en_US
dc.identifier.citedreferenceNIH Publication. Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults.; 1998. Available at: http://hp2010.nhlbihin.net/oei_ss/download/pdf/CORESET1.pdf. (accessed 2 May 2013).en_US
dc.identifier.citedreferenceBray G. A concise review on the therapeutics of obesity. Nutrition, 2000; 16: 953 – 960.en_US
dc.identifier.citedreferenceWeintraub M, Hasday J. A double‐blind clinical trial in weight control: use of fenfluramine and phentermine alone and in combination. Arch Intern Med, 1984; 144: 1143 – 1148.en_US
dc.identifier.citedreferenceGuy‐Grand B, Crepaldi G, Vre P International trial of long‐term dexfenfluramine in obesity. Lancet, 1989; 2: 1142 – 1145.en_US
dc.identifier.citedreferenceConnolly H, Crary J, McGoon M et al. Valvular heart disease associated with fenfluramine‐phentermine. N Engl J Med, 1997; 337: 581 – 588.en_US
dc.identifier.citedreferenceWee C, Phillips R, Aurigemma G et al. Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who underwent echocardiography before use of medication. Ann Intern Med, 1998; 129: 870 – 874.en_US
dc.identifier.citedreferenceSachdev M, Miller WC, Ryan T, Jollis JG. Effect of fenfluramine‐derivative diet pills on cardiac valves: a meta‐analysis of observational studies. Am Heart J, 2002; 144: 1065 – 1073. doi: 10.1067/mhj.2002.126733.en_US
dc.identifier.citedreferenceAbenhaim L, Moride Y, Brenot F et al. Appetite‐suppressant drugs and the risk of primary pulmonary hypertension. N Engl J Med, 1996; 335: 609 – 616. doi: 10.1381/096089297765556114.en_US
dc.identifier.citedreferenceRich S, Rubin L. Anorexigens and pulmonary hypertension in the United States: results from the surveillance of North American pulmonary hypertension. Chest, 2000; 117: 870 – 874.en_US
dc.identifier.citedreferenceRothman RB, Baumann MH, Savage JE et al. Evidence for possible involvement of 5‐HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications. Circulation, 2000; 102: 2836 – 2841.en_US
dc.identifier.citedreferenceRothman R, Baumann M. Serotonergic drugs and valvular heart disease. Expert Opin Drug Saf, 2009; 8: 317 – 329. doi: 10.1517/14740330902931524.Serotonergic.en_US
dc.identifier.citedreferenceFitzgerald LW, Burn TC, Brown BS et al. Possible role of valvular serotonin 5‐HT(2B) receptors in the cardiopathy associated with fenfluramine. Mol Pharmacol, 2000; 57: 75 – 81.en_US
dc.identifier.citedreferenceEddahibi S, Adnot S. Anorexigen‐induced pulmonary hypertension and the serotonin (5‐HT) hypothesis: lessons for the future in pathogenesis. Respir Res, 2002; 3: 1 – 4.en_US
dc.identifier.citedreferenceDempsie Y, MacLean MR. Pulmonary hypertension: therapeutic targets within the serotonin system. Br J Pharmacol, 2008; 155: 455 – 462. doi: 10.1038/bjp.2008.241.en_US
dc.identifier.citedreferenceScheen A. Cardiovascular risk‐benefit profile of sibutramine. Am J Cardiovasc Drugs, 2010; 10: 321 – 334.en_US
dc.identifier.citedreferenceProduct information. Meridia (sibutramine). Abbott Laboratories. 2001.en_US
dc.identifier.citedreferenceJames W, Caterson I. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med, 2010; 363: 905 – 917.en_US
dc.identifier.citedreferenceHaller CA, Jacob P, Benowitz NL. Pharmacology of ephedra alkaloids and caffeine after single‐dose dietary supplement use. Clin Pharmacol Ther. 2002; 71: 421 – 432. doi: 10.1067/mcp.2002.124523.en_US
dc.identifier.citedreferenceHaller CA, Benowitz NL. Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med, 2000; 343: 1833 – 1838. doi: 10.1056/NEJM200012213432502.en_US
dc.identifier.citedreferenceShekelle P, Hardy M, Morton S et al. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta‐analysis. JAMA, 2003; 289: 1537 – 1545.en_US
dc.identifier.citedreferenceDepartment of Health and Human Services. Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk; final rule. Fed Reg, 2004; 69: 6787 – 6854.en_US
dc.identifier.citedreferenceWhite L, Gardner S, Marx M, Wang P, Estes M. Pharmacokinetics and cardiovascular effects of ma‐huang ( Ephedra sinica ) in normotensive adults. J Clin Pharmacol, 1997; 37: 116 – 122.en_US
dc.identifier.citedreferencePalamar J. How ephedrine escaped regulation in the United States: a historical review of misuse and associated policy. Health Policy, 2011; 99: 1 – 9. doi: 10.1016/j.healthpol.2010.07.007.en_US
dc.identifier.citedreferenceBailes J, Cantu R, Day A. The neurosurgeon in sport: awareness of the risks of heatstroke and dietary supplements. Neurosurgery, 2002; 51: 283 – 288. doi: 10.1227/01.NEU.0000020569.68133.12.en_US
dc.identifier.citedreferenceKernan WN, Viscoli CM, Brass LM et al. Phenylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med, 2000; 343: 1826 – 1832. doi: 10.1056/NEJM200012213432501.en_US
dc.identifier.citedreferencePadwal RS, Majumdar SR. Drug treatments for obesity: orlistat, sibutramine, and rimonabant. Lancet, 2007; 369: 71 – 77. doi: 10.1016/S0140‐6736(07)60033‐6.en_US
dc.identifier.citedreferenceRucker D, Padwal R, Li SK, Curioni C, Lau DCW. Long term pharmacotherapy for obesity and overweight: updated meta‐analysis. BMJ, 2007; 335: 1194 – 1199. doi: 10.1136/bmj.39385.413113.25.en_US
dc.identifier.citedreferencePadwal R, Li S, Lau D Long‐term pharmacotherapy for obesity and overweight. Cochrane Database Syst Rev, 2004; 3: CD004094.en_US
dc.identifier.citedreferenceTorgeson J, Hauptman J, Boldrin M, Sjöström L. XENical in the prevention of diabetes in obese subjects (XENDOS) study. Diabetes Care, 2004; 27: 155 – 161.en_US
dc.identifier.citedreferenceHaddock CK, Poston WSC, Dill PL, Foreyt JP, Ericsson M. Pharmacotherapy for obesity: a quantitative analysis of four decades of published randomized clinical trials. Int J Obes Relat Metab Disord, 2002; 26: 262 – 273. doi: 10.1038/sj.ijo.0801889.en_US
dc.identifier.citedreferenceCharakida M, Finer N. Drug treatment of obesity in cardiovascular disease. Am J Cardiovasc Drugs, 2012; 12: 93 – 104. doi: 10.2165/11599000‐000000000‐00000.en_US
dc.identifier.citedreferenceKang JG, Park C‐Y. Anti‐obesity drugs: a review about their effects and safety. Diabetes Metab J, 2012; 36: 13 – 25. doi: 10.4093/dmj.2012.36.1.13.en_US
dc.identifier.citedreferenceMiller K. Serotonin 5‐HT2c receptor agonists: potential for the treatment of obesity. Mol Interv, 2005; 5: 282 – 291.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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