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Prevalence and Clinical Significance of Sterile Intra‐amniotic Inflammation in Patients with Preterm Labor and Intact Membranes
dc.contributor.authorRomero, Robertoen_US
dc.contributor.authorMiranda, Jeziden_US
dc.contributor.authorChaiworapongsa, Tinnakornen_US
dc.contributor.authorKorzeniewski, Steven J.en_US
dc.contributor.authorChaemsaithong, Piyaen_US
dc.contributor.authorGotsch, Francescaen_US
dc.contributor.authorDong, Zhongen_US
dc.contributor.authorAhmed, Ahmed I.en_US
dc.contributor.authorYoon, Bo Hyunen_US
dc.contributor.authorHassan, Sonia S.en_US
dc.contributor.authorKim, Chong Jaien_US
dc.contributor.authorYeo, Lamien_US
dc.date.accessioned2014-11-04T16:35:49Z
dc.date.availableWITHHELD_13_MONTHSen_US
dc.date.available2014-11-04T16:35:49Z
dc.date.issued2014-11en_US
dc.identifier.citationRomero, Roberto; Miranda, Jezid; Chaiworapongsa, Tinnakorn; Korzeniewski, Steven J.; Chaemsaithong, Piya; Gotsch, Francesca; Dong, Zhong; Ahmed, Ahmed I.; Yoon, Bo Hyun; Hassan, Sonia S.; Kim, Chong Jai; Yeo, Lami (2014). "Prevalence and Clinical Significance of Sterile Intra‐amniotic Inflammation in Patients with Preterm Labor and Intact Membranes." American Journal of Reproductive Immunology 72(5): 458-474.en_US
dc.identifier.issn1046-7408en_US
dc.identifier.issn1600-0897en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/109340
dc.publisherWiley Periodicals, Inc.en_US
dc.publisherElsevieren_US
dc.subject.otherPreterm Deliveryen_US
dc.subject.otherPolymerase Chain Reaction With Electrospray Ionization Mass Spectrometryen_US
dc.subject.otherHigh Mobility Group Box‐1en_US
dc.subject.otherDanger Signalen_US
dc.subject.otherA Larminsen_US
dc.subject.otherPregnancyen_US
dc.titlePrevalence and Clinical Significance of Sterile Intra‐amniotic Inflammation in Patients with Preterm Labor and Intact Membranesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMicrobiology and Immunologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/109340/1/aji12296.pdf
dc.identifier.doi10.1111/aji.12296en_US
dc.identifier.sourceAmerican Journal of Reproductive Immunologyen_US
dc.identifier.citedreferenceGreci LS, Gilson GJ, Nevils B, Izquierdo LA, Qualls CR, Curet LB: Is amniotic fluid analysis the key to preterm labor? A model using interleukin‐6 for predicting rapid delivery. Am J Obstet Gynecol 1998; 179: 172 – 178.en_US
dc.identifier.citedreferenceMedzhitov R, Janeway CA Jr: Innate immunity: the virtues of a nonclonal system of recognition. Cell 1997; 91: 295 – 298.en_US
dc.identifier.citedreferenceMedzhitov R, Janeway CA Jr: Self‐defense: the fruit fly style. Proc Natl Acad Sci U S A 1998; 95: 429 – 430.en_US
dc.identifier.citedreferenceMedzhitov R, Janeway CA Jr: How does the immune system distinguish self from nonself? Semin Immunol 2000; 12: 185 – 188; discussion 257‐344.en_US
dc.identifier.citedreferenceMedzhitov R, Janeway C Jr: Innate immune recognition: mechanisms and pathways. Immunol Rev 2000; 173: 89 – 97.en_US
dc.identifier.citedreferenceMedzhitov R, Janeway CA Jr: Decoding the patterns of self and nonself by the innate immune system. Science 2002; 296: 298 – 300.en_US
dc.identifier.citedreferenceMatzinger P: The danger model: a renewed sense of self. Science 2002; 296: 301 – 305.en_US
dc.identifier.citedreferenceKopp E, Medzhitov R: Recognition of microbial infection by Toll‐like receptors. Curr Opin Immunol 2003; 15: 396 – 401.en_US
dc.identifier.citedreferenceMedzhitov R: Toll‐like receptors and innate immunity. Nat Rev Immunol 2001; 1: 135 – 145.en_US
dc.identifier.citedreferencePiccinini AM, Midwood KS: DAMPening inflammation by modulating TLR signalling. Mediators Inflamm 2010; 2010: pii: 672395; doi: 10.1155/2010/672395.en_US
dc.identifier.citedreferenceBonaldi T, Talamo F, Scaffidi P, Ferrera D, Porto A, Bachi A, Rubartelli A, Agresti A, Bianchi ME: Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J 2003; 22: 5551 – 5560.en_US
dc.identifier.citedreferenceYang D, Chen Q, Yang H, Tracey KJ, Bustin M, Oppenheim JJ: High mobility group box‐1 protein induces the migration and activation of human dendritic cells and acts as an alarmin. J Leukoc Biol 2007; 81: 59 – 66.en_US
dc.identifier.citedreferenceDumitriu IE, Bianchi ME, Bacci M, Manfredi AA, Rovere‐Querini P: The secretion of HMGB1 is required for the migration of maturing dendritic cells. J Leukoc Biol 2007; 81: 84 – 91.en_US
dc.identifier.citedreferenceRouhiainen A, Kuja‐Panula J, Wilkman E, Pakkanen J, Stenfors J, Tuominen RK, Lepantalo M, Carpen O, Parkkinen J, Rauvala H: Regulation of monocyte migration by amphoterin (HMGB1). Blood 2004; 104: 1174 – 1182.en_US
dc.identifier.citedreferenceDeMarco RA, Fink MP, Lotze MT: Monocytes promote natural killer cell interferon gamma production in response to the endogenous danger signal HMGB1. Mol Immunol 2005; 42: 433 – 444.en_US
dc.identifier.citedreferenceLi J, Kokkola R, Tabibzadeh S, Yang R, Ochani M, Qiang X, Harris HE, Czura CJ, Wang H, Ulloa L, Warren HS, Moldawer LL, Fink MP, Andersson U, Tracey KJ, Yang H: Structural basis for the proinflammatory cytokine activity of high mobility group box 1. Mol Med 2003; 9: 37 – 45.en_US
dc.identifier.citedreferencePark JS, Arcaroli J, Yum HK, Yang H, Wang H, Yang KY, Choe KH, Strassheim D, Pitts TM, Tracey KJ, Abraham E: Activation of gene expression in human neutrophils by high mobility group box 1 protein. Am J Physiol Cell Physiol 2003; 284: C870 – C879.en_US
dc.identifier.citedreferenceSilva E, Arcaroli J, He Q, Svetkauskaite D, Coldren C, Nick JA, Poch K, Park JS, Banerjee A, Abraham E: HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis‐induced acute lung injury. Intensive Care Med 2007; 33: 1829 – 1839.en_US
dc.identifier.citedreferenceFan J, Li Y, Levy RM, Fan JJ, Hackam DJ, Vodovotz Y, Yang H, Tracey KJ, Billiar TR, Wilson MA: Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1‐TLR4 signaling. J Immunol 2007; 178: 6573 – 6580.en_US
dc.identifier.citedreferenceMessmer D, Yang H, Telusma G, Knoll F, Li J, Messmer B, Tracey KJ, Chiorazzi N: High mobility group box protein 1: an endogenous signal for dendritic cell maturation and Th1 polarization. J Immunol 2004; 173: 307 – 313.en_US
dc.identifier.citedreferenceDumitriu IE, Baruah P, Valentinis B, Voll RE, Herrmann M, Nawroth PP, Arnold B, Bianchi ME, Manfredi AA, Rovere‐Querini P: Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products. J Immunol 2005; 174: 7506 – 7515.en_US
dc.identifier.citedreferenceWang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, Frazier A, Yang H, Ivanova S, Borovikova L, Manogue KR, Faist E, Abraham E, Andersson J, Andersson U, Molina PE, Abumrad NN, Sama A, Tracey KJ: HMG‐1 as a late mediator of endotoxin lethality in mice. Science 1999; 285: 248 – 251.en_US
dc.identifier.citedreferenceWang H, Yang H, Czura CJ, Sama AE, Tracey KJ: HMGB1 as a late mediator of lethal systemic inflammation. Am J Respir Crit Care Med 2001; 164: 1768 – 1773.en_US
dc.identifier.citedreferenceCzura CJ, Tracey KJ: Targeting high mobility group box 1 as a late‐acting mediator of inflammation. Crit Care Med 2003; 31: S46 – S50.en_US
dc.identifier.citedreferenceTang D, Kang R, Xiao W, Zhang H, Lotze MT, Wang H, Xiao X: Quercetin prevents LPS‐induced high‐mobility group box 1 release and proinflammatory function. Am J Respir Cell Mol Biol 2009; 41: 651 – 660.en_US
dc.identifier.citedreferenceWang H, Ward MF, Sama AE: Novel HMGB1‐inhibiting therapeutic agents for experimental sepsis. Shock 2009; 32: 348 – 357.en_US
dc.identifier.citedreferenceRomero R, Mazor M, Tartakovsky B: Systemic administration of interleukin‐1 induces preterm parturition in mice. Am J Obstet Gynecol 1991; 165: 969 – 971.en_US
dc.identifier.citedreferenceRomero R, Tartakovsky B: The natural interleukin‐1 receptor antagonist prevents interleukin‐1‐induced preterm delivery in mice. Am J Obstet Gynecol 1992; 167: 1041 – 1045.en_US
dc.identifier.citedreferenceBry K, Hallman M: Transforming growth factor‐beta 2 prevents preterm delivery induced by interleukin‐1 alpha and tumor necrosis factor‐alpha in the rabbit. Am J Obstet Gynecol 1993; 168: 1318 – 1322.en_US
dc.identifier.citedreferenceGotsch F, Romero R, Chaiworapongsa T, Erez O, Vaisbuch E, Espinoza J, Kusanovic JP, Mittal P, Mazaki‐Tovi S, Kim CJ, Kim JS, Edwin S, Nhan‐Chang CL, Hamill N, Friel L, Than NG, Mazor M, Yoon BH, Hassan SS: Evidence of the involvement of caspase‐1 under physiologic and pathologic cellular stress during human pregnancy: a link between the inflammasome and parturition. J Matern Fetal Neonatal Med 2008; 21: 605 – 616.en_US
dc.identifier.citedreferenceGross O, Yazdi AS, Thomas CJ, Masin M, Heinz LX, Guarda G, Quadroni M, Drexler SK, Tschopp J: Inflammasome activators induce interleukin‐1 alpha secretion via distinct pathways with differential requirement for the protease function of caspase‐1. Immunity 2012; 36: 388 – 400.en_US
dc.identifier.citedreferenceYazdi AS, Drexler SK: Regulation of interleukin 1 alpha secretion by inflammasomes. Ann Rheum Dis 2013; 72 ( Suppl 2 ): ii96 – ii99.en_US
dc.identifier.citedreferenceMarch of Dimes, PMNCH, Save the Children, WHO. Born too soon: the global action report on preterm birth. CP Howson, MV Kinney, JE Lawn (eds). Geneva, World Health Organization, 2012.en_US
dc.identifier.citedreferenceBlencowe H, Cousens S, Oestergaard MZ, Chou D, Moller AB, Narwal R, Adler A, Vera Garcia C, Rohde S, Say L, Lawn JE: National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet 2012; 379: 2162 – 2172.en_US
dc.identifier.citedreferenceLiu L, Johnson HL, Cousens S, Perin J, Scott S, Lawn JE, Rudan I, Campbell H, Cibulskis R, Li M, Mathers C, Black RE: Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet 2012; 379: 2151 – 2161.en_US
dc.identifier.citedreferenceHamilton BE, Hoyert DL, Martin JA, Strobino DM, Guyer B: Annual summary of vital statistics: 2010‐2011. Pediatrics 2013; 131: 548 – 558.en_US
dc.identifier.citedreferenceMarch of Dimes. Premature Birth. Available at http://www.marchofdimes.com/peristats/. Accessed May 19, 2014.en_US
dc.identifier.citedreferenceMuglia LJ, Katz M: The enigma of spontaneous preterm birth. N Engl J Med 2010; 362: 529 – 535.en_US
dc.identifier.citedreferenceRomero R, Mazor M, Munoz H, Gomez R, Galasso M, Sherer DM: The preterm labor syndrome. Ann N Y Acad Sci 1994; 734: 414 – 429.en_US
dc.identifier.citedreferenceBerkowitz GS, Blackmore‐Prince C, Lapinski RH, Savitz DA: Risk factors for preterm birth subtypes. Epidemiology 1998; 9: 279 – 285.en_US
dc.identifier.citedreferenceMoutquin JM: Classification and heterogeneity of preterm birth. BJOG 2003; 110 ( Suppl 20 ): 30 – 33.en_US
dc.identifier.citedreferenceGoldenberg RL, Culhane JF, Iams JD, Romero R: Epidemiology and causes of preterm birth. Lancet 2008; 371: 75 – 84.en_US
dc.identifier.citedreferenceRomero R, Lockwood CJ: Pathogenesis of Spontaneous Preterm Labor. In Creasy and Resnik's Maternal‐Fetal Medicine: Principles and Practice, 6th edn. RK Creasy, R Resnik, J Iams (eds). Philadelphia, Elsevier, 2009, pp 521 – 543.en_US
dc.identifier.citedreferenceRomero R: The child is the father of the man. Prenat Neonat Med 1996; 1: 8 – 11.en_US
dc.identifier.citedreferenceRomero R, Gomez R, Mazor M, Ghezzi F, Yoon BH: The preterm labor syndrome. In Preterm labor. MG Elder, R Romero, RF Lamont (eds). New York, Churchill Livingstone, 1997, pp 29 – 49.en_US
dc.identifier.citedreferenceRomero R, Espinoza J, Kusanovic JP, Gotsch F, Hassan S, Erez O, Chaiworapongsa T, Mazor M: The preterm parturition syndrome. BJOG 2006; 113 ( Suppl 3 ): 17 – 42.en_US
dc.identifier.citedreferenceRomero R: Prenatal medicine: the child is the father of the man. 1996. J Matern Fetal Neonatal Med 2009; 22: 636 – 639.en_US
dc.identifier.citedreferenceGarfield RE, Hayashi RH: Appearance of gap junctions in the myometrium of women during labor. Am J Obstet Gynecol 1981; 140: 254 – 260.en_US
dc.identifier.citedreferenceHuszar G, Roberts JM: Biochemistry and pharmacology of the myometrium and labor: regulation at the cellular and molecular levels. Am J Obstet Gynecol 1982; 142: 225 – 237.en_US
dc.identifier.citedreferenceHsu HW, Figueroa JP, Honnebier MB, Wentworth R, Nathanielsz PW: Power spectrum analysis of myometrial electromyogram and intrauterine pressure changes in the pregnant rhesus monkey in late gestation. Am J Obstet Gynecol 1989; 161: 467 – 473.en_US
dc.identifier.citedreferenceBalducci J, Risek B, Gilula NB, Hand A, Egan JF, Vintzileos AM: Gap junction formation in human myometrium: a key to preterm labor? Am J Obstet Gynecol 1993; 168: 1609 – 1615.en_US
dc.identifier.citedreferenceChow L, Lye SJ: Expression of the gap junction protein connexin‐43 is increased in the human myometrium toward term and with the onset of labor. Am J Obstet Gynecol 1994; 170: 788 – 795.en_US
dc.identifier.citedreferenceAsboth G, Phaneuf S, Lopez Bernal AL: Prostaglandin E receptors in myometrial cells. Acta Physiol Hung 1997; 85: 39 – 50.en_US
dc.identifier.citedreferenceCook JL, Zaragoza DB, Sung DH, Olson DM: Expression of myometrial activation and stimulation genes in a mouse model of preterm labor: myometrial activation, stimulation, and preterm labor. Endocrinology 2000; 141: 1718 – 1728.en_US
dc.identifier.citedreferenceLye SJ, Mitchell J, Nashman N, Oldenhof A, Ou R, Shynlova O, Langille L: Role of mechanical signals in the onset of term and preterm labor. Front Horm Res 2001; 27: 165 – 178.en_US
dc.identifier.citedreferenceChan EC, Fraser S, Yin S, Yeo G, Kwek K, Fairclough RJ, Smith R: Human myometrial genes are differentially expressed in labor: a suppression subtractive hybridization study. J Clin Endocrinol Metab 2002; 87: 2435 – 2441.en_US
dc.identifier.citedreferenceSmith R: Parturition. N Engl J Med 2007; 356: 271 – 283.en_US
dc.identifier.citedreferencePierce SL, England SK: SK3 channel expression during pregnancy is regulated through estrogen and Sp factor‐mediated transcriptional control of the KCNN3 gene. Am J Physiol Endocrinol Metab 2010; 299: E640 – E646.en_US
dc.identifier.citedreferenceLiggins C: Cervical ripening as an inflammatory reaction. In The Cervix in Pregnancy and Labour: Clinical and Biochemical Investigations, D Ellwood, A Anderson (ed). Edinburgh, Churchill Livingstone, 1981, pp 1 – 9.en_US
dc.identifier.citedreferenceLeppert PC: Anatomy and physiology of cervical ripening. Clin Obstet Gynecol 1995; 38: 267 – 279.en_US
dc.identifier.citedreferenceLudmir J, Sehdev HM: Anatomy and physiology of the uterine cervix. Clin Obstet Gynecol 2000; 43: 433 – 439.en_US
dc.identifier.citedreferenceKelly RW: Inflammatory mediators and cervical ripening. J Reprod Immunol 2002; 57: 217 – 224.en_US
dc.identifier.citedreferenceStraach KJ, Shelton JM, Richardson JA, Hascall VC, Mahendroo MS: Regulation of hyaluronan expression during cervical ripening. Glycobiology 2005; 15: 55 – 65.en_US
dc.identifier.citedreferenceHassan SS, Romero R, Haddad R, Hendler I, Khalek N, Tromp G, Diamond MP, Sorokin Y, Malone J Jr: The transcriptome of the uterine cervix before and after spontaneous term parturition. Am J Obstet Gynecol 2006; 195: 778 – 786.en_US
dc.identifier.citedreferenceWord RA, Li XH, Hnat M, Carrick K: Dynamics of cervical remodeling during pregnancy and parturition: mechanisms and current concepts. Semin Reprod Med 2007; 25: 69 – 79.en_US
dc.identifier.citedreferenceHassan SS, Romero R, Tarca AL, Nhan‐Chang CL, Vaisbuch E, Erez O, Mittal P, Kusanovic JP, Mazaki‐Tovi S, Yeo L, Draghici S, Kim JS, Uldbjerg N, Kim CJ: The transcriptome of cervical ripening in human pregnancy before the onset of labor at term: identification of novel molecular functions involved in this process. J Matern Fetal Neonatal Med 2009; 22: 1183 – 1193.en_US
dc.identifier.citedreferenceLyttle B, Chai J, Gonzalez JM, Xu H, Sammel M, Elovitz MA: The negative regulators of the host immune response: an unexplored pathway in preterm birth. Am J Obstet Gynecol 2009; 201: 284.e281 – 284.e287.en_US
dc.identifier.citedreferenceGonzalez JM, Dong Z, Romero R, Girardi G: Cervical remodeling/ripening at term and preterm delivery: the same mechanism initiated by different mediators and different effector cells. PLoS ONE 2011; 6: e26877.en_US
dc.identifier.citedreferenceMahendroo M: Cervical remodeling in term and preterm birth: insights from an animal model. Reproduction 2012; 143: 429 – 438.en_US
dc.identifier.citedreferenceAkgul Y, Holt R, Mummert M, Word A, Mahendroo M: Dynamic changes in cervical glycosaminoglycan composition during normal pregnancy and preterm birth. Endocrinology 2012; 153: 3493 – 3503.en_US
dc.identifier.citedreferenceGonzalez JM, Romero R, Girardi G: Comparison of the mechanisms responsible for cervical remodeling in preterm and term labor. J Reprod Immunol 2013; 97: 112 – 119.en_US
dc.identifier.citedreferenceSkinner SJ, Liggins GC: Glycosaminoglycans and collagen in human amnion from pregnancies with and without premature rupture of the membranes. J Dev Physiol 1981; 3: 111 – 121.en_US
dc.identifier.citedreferenceAthayde N, Edwin SS, Romero R, Gomez R, Maymon E, Pacora P, Menon R: A role for matrix metalloproteinase‐9 in spontaneous rupture of the fetal membranes. Am J Obstet Gynecol 1998; 179: 1248 – 1253.en_US
dc.identifier.citedreferenceMcLaren J, Malak TM, Bell SC: Structural characteristics of term human fetal membranes prior to labour: identification of an area of altered morphology overlying the cervix. Hum Reprod 1999; 14: 237 – 241.en_US
dc.identifier.citedreferenceKeelan JA, Marvin KW, Sato TA, Coleman M, McCowan LM, Mitchell MD: Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition. Am J Obstet Gynecol 1999; 181: 1530 – 1536.en_US
dc.identifier.citedreferenceMaymon E, Romero R, Pacora P, Gomez R, Athayde N, Edwin S, Yoon BH: Human neutrophil collagenase (matrix metalloproteinase 8) in parturition, premature rupture of the membranes, and intrauterine infection. Am J Obstet Gynecol 2000; 183: 94 – 99.en_US
dc.identifier.citedreferenceMaymon E, Romero R, Pacora P, Gervasi MT, Bianco K, Ghezzi F, Yoon BH: Evidence for the participation of interstitial collagenase (matrix metalloproteinase 1) in preterm premature rupture of membranes. Am J Obstet Gynecol 2000; 183: 914 – 920.en_US
dc.identifier.citedreferenceMcLaren J, Taylor DJ, Bell SC: Increased concentration of pro‐matrix metalloproteinase 9 in term fetal membranes overlying the cervix before labor: implications for membrane remodeling and rupture. Am J Obstet Gynecol 2000; 182: 409 – 416.en_US
dc.identifier.citedreferenceUlug U, Goldman S, Ben‐Shlomo I, Shalev E: Matrix metalloproteinase (MMP)‐2 and MMP‐9 and their inhibitor, TIMP‐1, in human term decidua and fetal membranes: the effect of prostaglandin F(2alpha) and indomethacin. Mol Hum Reprod 2001; 7: 1187 – 1193.en_US
dc.identifier.citedreferenceMaymon E, Romero R, Pacora P, Gomez R, Mazor M, Edwin S, Chaiworapongsa T, Kim JC, Yoon BH, Menon R, Fortunato S, Berry SM: A role for the 72 kDa gelatinase (MMP‐2) and its inhibitor (TIMP‐2) in human parturition, premature rupture of membranes and intraamniotic infection. J Perinat Med 2001; 29: 308 – 316.en_US
dc.identifier.citedreferenceHelmig BR, Romero R, Espinoza J, Chaiworapongsa T, Bujold E, Gomez R, Ohlsson K, Uldbjerg N: Neutrophil elastase and secretory leukocyte protease inhibitor in prelabor rupture of membranes, parturition and intra‐amniotic infection. J Matern Fetal Neonatal Med 2002; 12: 237 – 246.en_US
dc.identifier.citedreferenceFortunato SJ, Menon R: Screening of novel matrix metalloproteinases (MMPs) in human fetal membranes. J Assist Reprod Genet 2002; 19: 483 – 486.en_US
dc.identifier.citedreferenceGoldman S, Weiss A, Eyali V, Shalev E: Differential activity of the gelatinases (matrix metalloproteinases 2 and 9) in the fetal membranes and decidua, associated with labour. Mol Hum Reprod 2003; 9: 367 – 373.en_US
dc.identifier.citedreferenceHaddad R, Tromp G, Kuivaniemi H, Chaiworapongsa T, Kim YM, Mazor M, Romero R: Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am J Obstet Gynecol 2006; 195: 394 e391 – 324.en_US
dc.identifier.citedreferenceThan NG, Romero R, Tarca AL, Draghici S, Erez O, Chaiworapongsa T, Kim YM, Kim SK, Vaisbuch E, Tromp G: Mitochondrial manganese superoxide dismutase mRNA expression in human chorioamniotic membranes and its association with labor, inflammation, and infection. J Matern Fetal Neonatal Med 2009; 22: 1000 – 1013.en_US
dc.identifier.citedreferenceNunez G: Intracellular sensors of microbes and danger. Immunol Rev 2011; 243: 5 – 8.en_US
dc.identifier.citedreferenceBollapragada S, Youssef R, Jordan F, Greer I, Norman J, Nelson S: Term labor is associated with a core inflammatory response in human fetal membranes, myometrium, and cervix. Am J Obstet Gynecol 2009; 200: 104 e101 – 104 e111.en_US
dc.identifier.citedreferenceHolzman C, Senagore PK, Wang J: Mononuclear leukocyte infiltrate in extraplacental membranes and preterm delivery. Am J Epidemiol 2013; 177: 1053 – 1064.en_US
dc.identifier.citedreferenceBobitt JR, Ledger WJ: Unrecognized amnionitis and prematurity: a preliminary report. J Reprod Med 1977; 19: 8 – 12.en_US
dc.identifier.citedreferenceBobitt JR, Ledger WJ: Amniotic fluid analysis. Its role in maternal neonatal infection. Obstet Gynecol 1978; 51: 56 – 62.en_US
dc.identifier.citedreferenceMiller JM Jr, Pupkin MJ, Hill GB: Bacterial colonization of amniotic fluid from intact fetal membranes. Am J Obstet Gynecol 1980; 136: 796 – 804.en_US
dc.identifier.citedreferenceBobitt JR, Hayslip CC, Damato JD: Amniotic fluid infection as determined by transabdominal amniocentesis in patients with intact membranes in premature labor. Am J Obstet Gynecol 1981; 140: 947 – 952.en_US
dc.identifier.citedreferenceWallace RL, Herrick CN: Amniocentesis in the evaluation of premature labor. Obstet Gynecol 1981; 57: 483 – 486.en_US
dc.identifier.citedreferenceWahbeh CJ, Hill GB, Eden RD, Gall SA: Intra‐amniotic bacterial colonization in premature labor. Am J Obstet Gynecol 1984; 148: 739 – 743.en_US
dc.identifier.citedreferenceRomero R, Mazor M, Wu YK, Sirtori M, Oyarzun E, Mitchell MD, Hobbins JC: Infection in the pathogenesis of preterm labor. Semin Perinatol 1988; 12: 262 – 279.en_US
dc.identifier.citedreferenceRomero R, Mazor M: Infection and preterm labor. Clin Obstet Gynecol 1988; 31: 553 – 584.en_US
dc.identifier.citedreferenceRomero R, Sirtori M, Oyarzun E, Avila C, Mazor M, Callahan R, Sabo V, Athanassiadis AP, Hobbins JC: Infection and labor. V. Prevalence, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes. Am J Obstet Gynecol 1989; 161: 817 – 824.en_US
dc.identifier.citedreferenceRomero R, Avila C, Brekus CA, Morotti R: The role of systemic and intrauterine infection in preterm parturition. Ann N Y Acad Sci 1991; 622: 355 – 375.en_US
dc.identifier.citedreferenceWatts DH, Krohn MA, Hillier SL, Eschenbach DA: The association of occult amniotic fluid infection with gestational age and neonatal outcome among women in preterm labor. Obstet Gynecol 1992; 79: 351 – 357.en_US
dc.identifier.citedreferenceGibbs RS, Romero R, Hillier SL, Eschenbach DA, Sweet RL: A review of premature birth and subclinical infection. Am J Obstet Gynecol 1992; 166: 1515 – 1528.en_US
dc.identifier.citedreferenceRomero R, Munoz H, Gomez R, Galasso M, Sherer DM, Cotton DB, Mitchell MD: Does infection cause premature labor and delivery? Semin Reprod Endocrinol 1994; 12: 227 – 239.en_US
dc.identifier.citedreferenceGomez R, Romero R, Edwin SS, David C: Pathogenesis of preterm labor and preterm premature rupture of membranes associated with intraamniotic infection. Infect Dis Clin North Am 1997; 11: 135 – 176.en_US
dc.identifier.citedreferenceRomero R, Gomez R, Chaiworapongsa T, Conoscenti G, Kim JC, Kim YM: The role of infection in preterm labour and delivery. Paediatr Perinat Epidemiol 2001; 15 ( Suppl 2 ): 41 – 56.en_US
dc.identifier.citedreferenceYoon BH, Romero R, Moon JB, Oh SY, Han SY, Kim JC, Shim SS: The frequency and clinical significance of intra‐amniotic inflammation in patients with a positive cervical fetal fibronectin. Am J Obstet Gynecol 2001; 185: 1137 – 1142.en_US
dc.identifier.citedreferenceYoon BH, Romero R, Moon JB, Shim SS, Kim M, Kim G, Jun JK: Clinical significance of intra‐amniotic inflammation in patients with preterm labor and intact membranes. Am J Obstet Gynecol 2001; 185: 1130 – 1136.en_US
dc.identifier.citedreferenceRomero R, Espinoza J, Chaiworapongsa T, Kalache K: Infection and prematurity and the role of preventive strategies. Semin Neonatol 2002; 7: 259 – 274.en_US
dc.identifier.citedreferenceShim SS, Romero R, Hong JS, Park CW, Jun JK, Kim BI, Yoon BH: Clinical significance of intra‐amniotic inflammation in patients with preterm premature rupture of membranes. Am J Obstet Gynecol 2004; 191: 1339 – 1345.en_US
dc.identifier.citedreferenceRomero R, Gotsch F, Pineles B, Kusanovic JP: Inflammation in pregnancy: its roles in reproductive physiology, obstetrical complications, and fetal injury. Nutr Rev 2007; 65: S194 – S202.en_US
dc.identifier.citedreferenceLee SE, Romero R, Jung H, Park CW, Park JS, Yoon BH: The intensity of the fetal inflammatory response in intraamniotic inflammation with and without microbial invasion of the amniotic cavity. Am J Obstet Gynecol 2007; 197: 294 e291 – 294 e296.en_US
dc.identifier.citedreferenceLee SE, Romero R, Park CW, Jun JK, Yoon BH: The frequency and significance of intraamniotic inflammation in patients with cervical insufficiency. Am J Obstet Gynecol 2008; 198: 633 e631 – 633 e638.en_US
dc.identifier.citedreferenceLee SE, Romero R, Lee SM, Yoon BH: Amniotic fluid volume in intra‐amniotic inflammation with and without culture‐proven amniotic fluid infection in preterm premature rupture of membranes. J Perinat Med 2010; 38: 39 – 44.en_US
dc.identifier.citedreferenceMadan I, Romero R, Kusanovic JP, Mittal P, Chaiworapongsa T, Dong Z, Mazaki‐Tovi S, Vaisbuch E, Alpay Savasan Z, Yeo L, Kim CJ, Hassan SS: The frequency and clinical significance of intra‐amniotic infection and/or inflammation in women with placenta previa and vaginal bleeding: an unexpected observation. J Perinat Med 2010; 38: 275 – 279.en_US
dc.identifier.citedreferenceKim SM, Romero R, Lee J, Mi Lee S, Park CW, Shin Park J, Yoon BH: The frequency and clinical significance of intra‐amniotic inflammation in women with preterm uterine contractility but without cervical change: do the diagnostic criteria for preterm labor need to be changed? J Matern Fetal Neonatal Med 2012; 25: 1212 – 1221.en_US
dc.identifier.citedreferenceMinkoff H: Prematurity: infection as an etiologic factor. Obstet Gynecol 1983; 62: 137 – 144.en_US
dc.identifier.citedreferenceRomero R, Kadar N, Hobbins JC, Duff GW: Infection and labor: the detection of endotoxin in amniotic fluid. Am J Obstet Gynecol 1987; 157: 815 – 819.en_US
dc.identifier.citedreferenceRomero R, Emamian M, Wan M, Quintero R, Hobbins JC, Mitchell MD: Prostaglandin concentrations in amniotic fluid of women with intra‐amniotic infection and preterm labor. Am J Obstet Gynecol 1987; 157: 1461 – 1467.en_US
dc.identifier.citedreferenceCox SM, MacDonald PC, Casey ML: Assay of bacterial endotoxin (lipopolysaccharide) in human amniotic fluid: potential usefulness in diagnosis and management of preterm labor. Am J Obstet Gynecol 1988; 159: 99 – 106.en_US
dc.identifier.citedreferenceRomero R, Roslansky P, Oyarzun E, Wan M, Emamian M, Novitsky TJ, Gould MJ, Hobbins JC: Labor and infection. II. Bacterial endotoxin in amniotic fluid and its relationship to the onset of preterm labor. Am J Obstet Gynecol 1988; 158: 1044 – 1049.en_US
dc.identifier.citedreferenceRomero R, Brody DT, Oyarzun E, Mazor M, Wu YK, Hobbins JC, Durum SK: Infection and labor. III. Interleukin‐1: a signal for the onset of parturition. Am J Obstet Gynecol 1989; 160: 1117 – 1123.en_US
dc.identifier.citedreferenceRomero R, Manogue KR, Mitchell MD, Wu YK, Oyarzun E, Hobbins JC, Cerami A: Infection and labor. IV. Cachectin‐tumor necrosis factor in the amniotic fluid of women with intraamniotic infection and preterm labor. Am J Obstet Gynecol 1989; 161: 336 – 341.en_US
dc.identifier.citedreferenceMcDuffie RS Jr: Sherman MP, Gibbs RS: Amniotic fluid tumor necrosis factor‐alpha and interleukin‐1 in a rabbit model of bacterially induced preterm pregnancy loss. Am J Obstet Gynecol 1992; 167: 1583 – 1588.en_US
dc.identifier.citedreferenceRomero R, Mazor M, Brandt F, Sepulveda W, Avila C, Cotton DB, Dinarello CA: Interleukin‐1 alpha and interleukin‐1 beta in preterm and term human parturition. Am J Reprod Immunol 1992; 27: 117 – 123.en_US
dc.identifier.citedreferenceRomero R, Sepulveda W, Kenney JS, Archer LE, Allison AC, Sehgal PB: Interleukin 6 determination in the detection of microbial invasion of the amniotic cavity. Ciba Found Symp 1992; 167: 205 – 220.en_US
dc.identifier.citedreferenceGreig PC, Ernest JM, Teot L, Erikson M, Talley R: Amniotic fluid interleukin‐6 levels correlate with histologic chorioamnionitis and amniotic fluid cultures in patients in premature labor with intact membranes. Am J Obstet Gynecol 1993; 169: 1035 – 1044.en_US
dc.identifier.citedreferenceHillier SL, Witkin SS, Krohn MA, Watts DH, Kiviat NB, Eschenbach DA: The relationship of amniotic fluid cytokines and preterm delivery, amniotic fluid infection, histologic chorioamnionitis, and chorioamnion infection. Obstet Gynecol 1993; 81: 941 – 948.en_US
dc.identifier.citedreferenceGravett MG, Witkin SS, Haluska GJ, Edwards JL, Cook MJ, Novy MJ: An experimental model for intraamniotic infection and preterm labor in rhesus monkeys. Am J Obstet Gynecol 1994; 171: 1660 – 1667.en_US
dc.identifier.citedreferenceFidel PL Jr, Romero R, Wolf N, Cutright J, Ramirez M, Araneda H, Cotton DB: Systemic and local cytokine profiles in endotoxin‐induced preterm parturition in mice. Am J Obstet Gynecol 1994; 170: 1467 – 1475.en_US
dc.identifier.citedreferenceGomez R, Ghezzi F, Romero R, Munoz H, Tolosa JE, Rojas I: Premature labor and intra‐amniotic infection. Clinical aspects and role of the cytokines in diagnosis and pathophysiology. Clin Perinatol 1995; 22: 281 – 342.en_US
dc.identifier.citedreferenceYoon BH, Romero R, Kim CJ, Jun JK, Gomez R, Choi JH, Syn HC: Amniotic fluid interleukin‐6: a sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity. Am J Obstet Gynecol 1995; 172: 960 – 970.en_US
dc.identifier.citedreferenceGarry D, Figueroa R, Aguero‐Rosenfeld M, Martinez E, Visintainer P, Tejani N: A comparison of rapid amniotic fluid markers in the prediction of microbial invasion of the uterine cavity and preterm delivery. Am J Obstet Gynecol 1996; 175: 1336 – 1341.en_US
dc.identifier.citedreferenceFortunato SJ, Menon RP, Swan KF, Menon R: Inflammatory cytokine (interleukins 1, 6 and 8 and tumor necrosis factor‐alpha) release from cultured human fetal membranes in response to endotoxic lipopolysaccharide mirrors amniotic fluid concentrations. Am J Obstet Gynecol 1996; 174: 1855 – 1861; discussion 1861‐1852.en_US
dc.identifier.citedreferenceHsu CD, Meaddough E, Aversa K, Hong SF, Lu LC, Jones DC, Copel JA: Elevated amniotic fluid levels of leukemia inhibitory factor, interleukin 6, and interleukin 8 in intra‐amniotic infection. Am J Obstet Gynecol 1998; 179: 1267 – 1270.en_US
dc.identifier.citedreferenceOdibo AO, Rodis JF, Sanders MM, Borgida AF, Wilson M, Egan JF, Campbell WA: Relationship of amniotic fluid markers of intra‐amniotic infection with histopathology in cases of preterm labor with intact membranes. J Perinatol 1999; 19: 407 – 412.en_US
dc.identifier.citedreferenceRomero R, Mazor M, Sepulveda W, Avila C, Copeland D, Williams J: Tumor necrosis factor in preterm and term labor. Am J Obstet Gynecol 1992; 166: 1576 – 1587.en_US
dc.identifier.citedreferenceBaumann P, Romero R, Berry S, Gomez R, McFarlin B, Araneda H, Cotton DB, Fidel P: Evidence of participation of the soluble tumor necrosis factor receptor I in the host response to intrauterine infection in preterm labor. Am J Reprod Immunol 1993; 30: 184 – 193.en_US
dc.identifier.citedreferenceLaham N, Brennecke SP, Bendtzen K, Rice GE: Tumour necrosis factor alpha during human pregnancy and labour: maternal plasma and amniotic fluid concentrations and release from intrauterine tissues. Eur J Endocrinol 1994; 131: 607 – 614.en_US
dc.identifier.citedreferenceMaymon E, Ghezzi F, Edwin SS, Mazor M, Yoon BH, Gomez R, Romero R: The tumor necrosis factor alpha and its soluble receptor profile in term and preterm parturition. Am J Obstet Gynecol 1999; 181: 1142 – 1148.en_US
dc.identifier.citedreferenceRomero R, Ceska M, Avila C, Mazor M, Behnke E, Lindley I: Neutrophil attractant/activating peptide‐1/interleukin‐8 in term and preterm parturition. Am J Obstet Gynecol 1991; 165: 813 – 820.en_US
dc.identifier.citedreferencePasare C, Medzhitov R: Toll‐like receptors: linking innate and adaptive immunity. Microbes Infect 2004; 6: 1382 – 1387.en_US
dc.identifier.citedreferenceCherouny PH, Pankuch GA, Romero R, Botti JJ, Kuhn DC, Demers LM, Appelbaum PC: Neutrophil attractant/activating peptide‐1/interleukin‐8: association with histologic chorioamnionitis, preterm delivery, and bioactive amniotic fluid leukoattractants. Am J Obstet Gynecol 1993; 169: 1299 – 1303.en_US
dc.identifier.citedreferenceRomero R, Gomez R, Galasso M, Munoz H, Acosta L, Yoon BH, Svinarich D, Cotton DB: Macrophage inflammatory protein‐1 alpha in term and preterm parturition: effect of microbial invasion of the amniotic cavity. Am J Reprod Immunol 1994; 32: 108 – 113.en_US
dc.identifier.citedreferenceGravett MG, Novy MJ: Endocrine‐immune interactions in pregnant non‐human primates with intrauterine infection. Infect Dis Obstet Gynecol 1997; 5: 142 – 153.en_US
dc.identifier.citedreferenceDudley DJ: Pre‐term labor: an intra‐uterine inflammatory response syndrome? J Reprod Immunol 1997; 36: 93 – 109.en_US
dc.identifier.citedreferenceAthayde N, Romero R, Maymon E, Gomez R, Pacora P, Araneda H: Yoon BH: a role for the novel cytokine RANTES in pregnancy and parturition. Am J Obstet Gynecol 1999; 181: 989 – 994.en_US
dc.identifier.citedreferencePacora P, Romero R, Maymon E, Gervasi MT, Gomez R, Edwin SS, Yoon BH: Participation of the novel cytokine interleukin 18 in the host response to intra‐amniotic infection. Am J Obstet Gynecol 2000; 183: 1138 – 1143.en_US
dc.identifier.citedreferenceElovitz MA, Wang Z, Chien EK, Rychlik DF, Phillippe M: A new model for inflammation‐induced preterm birth: the role of platelet‐activating factor and Toll‐like receptor‐4. Am J Pathol 2003; 163: 2103 – 2111.en_US
dc.identifier.citedreferenceEsplin MS, Romero R, Chaiworapongsa T, Kim YM, Edwin S, Gomez R, Mazor M, Adashi EY: Monocyte chemotactic protein‐1 is increased in the amniotic fluid of women who deliver preterm in the presence or absence of intra‐amniotic infection. J Matern Fetal Neonatal Med 2005; 17: 365 – 373.en_US
dc.identifier.citedreferenceFigueroa R, Garry D, Elimian A, Patel K, Sehgal PB, Tejani N: Evaluation of amniotic fluid cytokines in preterm labor and intact membranes. J Matern Fetal Neonatal Med 2005; 18: 241 – 247.en_US
dc.identifier.citedreferenceChaiworapongsa T, Romero R, Espinoza J, Kim YM, Edwin S, Bujold E, Gomez R, Kuivaniemi H: Macrophage migration inhibitory factor in patients with preterm parturition and microbial invasion of the amniotic cavity. J Matern Fetal Neonatal Med 2005; 18: 405 – 416.en_US
dc.identifier.citedreferenceThaxton JE, Nevers TA, Sharma S: TLR‐mediated preterm birth in response to pathogenic agents. Infect Dis Obstet Gynecol 2010; 2010: pii: 378472. doi: 10.1155/2010/378472.en_US
dc.identifier.citedreferenceChoi SJ, Jung SH, Eom M, Han KH, Chung IB, Kim SK: Immunohistochemical distribution of toll‐like receptor 4 in preterm human fetal membrane. J Obstet Gynaecol Res 2012; 38: 108 – 112.en_US
dc.identifier.citedreferenceKacerovsky M, Musilova I, Khatibi A, Skogstrand K, Hougaard DM, Tambor V, Tosner J, Jacobsson B: Intraamniotic inflammatory response to bacteria: analysis of multiple amniotic fluid proteins in women with preterm prelabor rupture of membranes. J Matern Fetal Neonatal Med 2012; 25: 2014 – 2019.en_US
dc.identifier.citedreferenceAbrahams VM, Potter JA, Bhat G, Peltier MR, Saade G, Menon R: Bacterial modulation of human fetal membrane Toll‐like receptor expression. Am J Reprod Immunol 2013; 69: 33 – 40.en_US
dc.identifier.citedreferenceJacobsson B: Intra‐amniotic infection and inflammation in preterm birth–is bacteria always the connection? Commentary on the article by Miralles et al. on page 570 Pediatr Res 2005; 57: 473 – 474.en_US
dc.identifier.citedreferenceRomero R, Espinoza J, Goncalves LF, Kusanovic JP, Friel L, Hassan S: The role of inflammation and infection in preterm birth. Semin Reprod Med 2007; 25: 21 – 39.en_US
dc.identifier.citedreferenceChristiaens I, Zaragoza DB, Guilbert L, Robertson SA, Mitchell BF, Olson DM: Inflammatory processes in preterm and term parturition. J Reprod Immunol 2008; 79: 50 – 57.en_US
dc.identifier.citedreferenceVrachnis N, Vitoratos N, Iliodromiti Z, Sifakis S, Deligeoroglou E, Creatsas G: Intrauterine inflammation and preterm delivery. Ann N Y Acad Sci 2010; 1205: 118 – 122.en_US
dc.identifier.citedreferenceEspinoza J, Romero R, Chaiworapongsa T, Kim JC, Yoshimatsu J, Edwin S, Rathnasabapathy C, Tolosa J, Donnenfeld A, Craparo F, Gomez R, Bujold E: Lipopolysaccharide‐binding protein in microbial invasion of the amniotic cavity and human parturition. J Matern Fetal Neonatal Med 2002; 12: 313 – 321.en_US
dc.identifier.citedreferenceFriel LA, Romero R, Edwin S, Nien JK, Gomez R, Chaiworapongsa T, Kusanovic JP, Tolosa JE, Hassan SS, Espinoza J: The calcium binding protein, S100B, is increased in the amniotic fluid of women with intra‐amniotic infection/inflammation and preterm labor with intact or ruptured membranes. J Perinat Med 2007; 35: 385 – 393.en_US
dc.identifier.citedreferenceRomero R, Espinoza J, Hassan S, Gotsch F, Kusanovic JP, Avila C, Erez O, Edwin S, Schmidt AM: Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: modulation by infection and inflammation. J Perinat Med 2008; 36: 388 – 398.en_US
dc.identifier.citedreferenceChaiworapongsa T, Erez O, Kusanovic JP, Vaisbuch E, Mazaki‐Tovi S, Gotsch F, Than NG, Mittal P, Kim YM, Camacho N, Edwin S, Gomez R, Hassan SS, Romero R: Amniotic fluid heat shock protein 70 concentration in histologic chorioamnionitis, term and preterm parturition. J Matern Fetal Neonatal Med 2008; 21: 449 – 461.en_US
dc.identifier.citedreferenceLee SE, Park IS, Romero R, Yoon BH: Amniotic fluid prostaglandin F2 increases even in sterile amniotic fluid and is an independent predictor of impending delivery in preterm premature rupture of membranes. J Matern Fetal Neonatal Med 2009; 22: 880 – 886.en_US
dc.identifier.citedreferenceRomero R, Chaiworapongsa T, Alpay Savasan Z, Xu Y, Hussein Y, Dong Z, Kusanovic JP, Kim CJ, Hassan SS: Damage‐associated molecular patterns (DAMPs) in preterm labor with intact membranes and preterm PROM: a study of the alarmin HMGB1. J Matern Fetal Neonatal Med 2011; 24: 1444 – 1455.en_US
dc.identifier.citedreferenceChaiworapongsa T, Romero R, Chaemsaithong P, Miranda J, Dong Z, Hassan S: Rapid detection of microbial invasion of amniotic cavity with molecular microbiologic techniques and the intra‐amniotic inflammatory response in preterm labor with intact membranes: diagnostic, prognostic and therapeutic implications. Am J Reprod Immunol 2013; 69: 48.en_US
dc.identifier.citedreferenceRomero R, Chaiworapongsa T, Savasan ZA, Hussein Y, Dong Z, Kusanovic JP, Kim CJ, Hassan SS: Clinical chorioamnionitis is characterized by changes in the expression of the alarmin HMGB1 and one of its receptors, sRAGE. J Matern Fetal Neonatal Med 2012; 25: 558 – 567.en_US
dc.identifier.citedreference‐Romero R, Durum S, Dinarello CA, Oyarzun E, Hobbins JC, Mitchell MD: Interleukin‐1 stimulates prostaglandin biosynthesis by human amnion. Prostaglandins 1989; 37: 13 – 22.en_US
dc.identifier.citedreferenceScaffidi P, Misteli T, Bianchi ME: Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002; 418: 191 – 195.en_US
dc.identifier.citedreferenceErlandsson Harris H, Andersson U: Mini‐review: the nuclear protein HMGB1 as a proinflammatory mediator. Eur J Immunol 2004; 34: 1503 – 1512.en_US
dc.identifier.citedreferenceRovere‐Querini P, Capobianco A, Scaffidi P, Valentinis B, Catalanotti F, Giazzon M, Dumitriu IE, Muller S, Iannacone M, Traversari C, Bianchi ME, Manfredi AA: HMGB1 is an endogenous immune adjuvant released by necrotic cells. EMBO Rep 2004; 5: 825 – 830.en_US
dc.identifier.citedreferenceChen G, Ward MF, Sama AE, Wang H: Extracellular HMGB1 as a proinflammatory cytokine. J Interferon Cytokine Res 2004; 24: 329 – 333.en_US
dc.identifier.citedreferenceLotze MT, Tracey KJ: High‐mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 2005; 5: 331 – 342.en_US
dc.identifier.citedreferenceDumitriu IE, Baruah P, Manfredi AA, Bianchi ME, Rovere‐Querini P: HMGB1: guiding immunity from within. Trends Immunol 2005; 26: 381 – 387.en_US
dc.identifier.citedreferenceHarris HE, Raucci A: Alarmin(g) news about danger: workshop on innate danger signals and HMGB1. EMBO Rep 2006; 7: 774 – 778.en_US
dc.identifier.citedreferenceBianchi ME, Manfredi AA: High‐mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity. Immunol Rev 2007; 220: 35 – 46.en_US
dc.identifier.citedreferenceKlune JR, Dhupar R, Cardinal J, Billiar TR, Tsung A: HMGB1: endogenous danger signaling. Mol Med 2008; 14: 476 – 484.en_US
dc.identifier.citedreferenceCastiglioni A, Canti V, Rovere‐Querini P, Manfredi AA: High‐mobility group box 1 (HMGB1) as a master regulator of innate immunity. Cell Tissue Res 2011; 343: 189 – 199.en_US
dc.identifier.citedreferenceAndersson U, Tracey KJ: HMGB1 in sepsis. Scand J Infect Dis 2003; 35: 577 – 584.en_US
dc.identifier.citedreferenceOppenheim JJ, Tewary P, de la Rosa G, Yang D: Alarmins initiate host defense. Adv Exp Med Biol 2007; 601: 185 – 194.en_US
dc.identifier.citedreferenceBianchi ME: DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 2007; 81: 1 – 5.en_US
dc.identifier.citedreferenceFoell D, Wittkowski H, Roth J: Mechanisms of disease: a ‘DAMP’ view of inflammatory arthritis. Nat Clin Pract Rheumatol 2007; 3: 382 – 390.en_US
dc.identifier.citedreferenceGauley J, Pisetsky DS: The translocation of HMGB1 during cell activation and cell death. Autoimmunity 2009; 42: 299 – 301.en_US
dc.identifier.citedreferenceHreggvidsdottir HS, Ostberg T, Wahamaa H, Schierbeck H, Aveberger AC, Klevenvall L, Palmblad K, Ottosson L, Andersson U, Harris HE: The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation. J Leukoc Biol 2009; 86: 655 – 662.en_US
dc.identifier.citedreferenceAndersson U, Tracey KJ: HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol 2011; 29: 139 – 162.en_US
dc.identifier.citedreferenceHarris HE, Andersson U, Pisetsky DS: HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease. Nat Rev Rheumatol 2012; 8: 195 – 202.en_US
dc.identifier.citedreferenceDiener KR, Al‐Dasooqi N, Lousberg EL, Hayball JD: The multifunctional alarmin HMGB1 with roles in the pathophysiology of sepsis and cancer. Immunol Cell Biol 2013; 91: 443 – 450.en_US
dc.identifier.citedreferenceAndersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, Erlandsson‐Harris H, Janson A, Kokkola R, Zhang M, Yang H, Tracey KJ: High mobility group 1 protein (HMG‐1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 2000; 192: 565 – 570.en_US
dc.identifier.citedreferenceGardella S, Andrei C, Ferrera D, Lotti LV, Torrisi MR, Bianchi ME, Rubartelli A: The nuclear protein HMGB1 is secreted by monocytes via a non‐classical, vesicle‐mediated secretory pathway. EMBO Rep 2002; 3: 995 – 1001.en_US
dc.identifier.citedreferenceChen GY, Nunez G: Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol 2010; 10: 826 – 837.en_US
dc.identifier.citedreferenceKim KW, Romero R, Park HS, Park CW, Shim SS, Jun JK, Yoon BH: A rapid matrix metalloproteinase‐8 bedside test for the detection of intraamniotic inflammation in women with preterm premature rupture of membranes. Am J Obstet Gynecol 2007; 197: 292 e291 – 292 e295.en_US
dc.identifier.citedreferenceYoon BH, Romero R, Park JS, Kim M, Oh SY, Kim CJ, Jun JK: The relationship among inflammatory lesions of the umbilical cord (funisitis), umbilical cord plasma interleukin 6 concentration, amniotic fluid infection, and neonatal sepsis. Am J Obstet Gynecol 2000; 183: 1124 – 1129.en_US
dc.identifier.citedreferencePacora P, Chaiworapongsa T, Maymon E, Kim YM, Gomez R, Yoon BH, Ghezzi F, Berry SM, Qureshi F, Jacques SM, Kim JC, Kadar N, Romero R: Funisitis and chorionic vasculitis: the histological counterpart of the fetal inflammatory response syndrome. J Matern Fetal Neonatal Med 2002; 11: 18 – 25.en_US
dc.identifier.citedreferenceHargreaves DC, Medzhitov R: Innate sensors of microbial infection. J Clin Immunol 2005; 25: 503 – 510.en_US
dc.identifier.citedreferenceRedline RW, Heller D, Keating S, Kingdom J: Placental diagnostic criteria and clinical correlation–a workshop report. Placenta 2005; 26 ( Suppl A ): S114 – S117.en_US
dc.identifier.citedreferenceRedline RW: Inflammatory responses in the placenta and umbilical cord. Semin Fetal Neonatal Med 2006; 11: 296 – 301.en_US
dc.identifier.citedreferenceEshoo MW, Crowder CC, Rebman AW, Rounds MA, Matthews HE, Picuri JM, Soloski MJ, Ecker DJ, Schutzer SE, Aucott JN: Direct molecular detection and genotyping of Borrelia burgdorferi from whole blood of patients with early Lyme disease. PLoS ONE 2012; 7: e36825.en_US
dc.identifier.citedreferenceShin JH, Ranken R, Sefers SE, Lovari R, Quinn CD, Meng S, Carolan HE, Toleno D, Li H, Lee JN, Stratton CW, Massire C, Tang YW: Detection, identification, and distribution of fungi in bronchoalveolar lavage specimens by use of multilocus PCR coupled with electrospray ionization/mass spectrometry. J Clin Microbiol 2013; 51: 136 – 141.en_US
dc.identifier.citedreferenceKaleta EJ, Clark AE, Johnson DR, Gamage DC, Wysocki VH, Cherkaoui A, Schrenzel J, Wolk DM: Use of PCR coupled with electrospray ionization mass spectrometry for rapid identification of bacterial and yeast bloodstream pathogens from blood culture bottles. J Clin Microbiol 2011; 49: 345 – 353.en_US
dc.identifier.citedreferenceEcker DJ, Sampath R, Li H, Massire C, Matthews HE, Toleno D, Hall TA, Blyn LB, Eshoo MW, Ranken R, Hofstadler SA, Tang YW: New technology for rapid molecular diagnosis of bloodstream infections. Expert Rev Mol Diagn 2010; 10: 399 – 415.en_US
dc.identifier.citedreferenceMetzgar D, Frinder M, Lovari R, Toleno D, Massire C, Blyn LB, Ranken R, Carolan HE, Hall TA, Moore D, Hansen CJ, Sampath R, Ecker DJ: Broad‐spectrum biosensor capable of detecting and identifying diverse bacterial and Candida species in blood. J Clin Microbiol 2013; 51: 2670 – 2678.en_US
dc.identifier.citedreferenceKanneganti TD, Ozoren N, Body‐Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Nunez G: Bacterial RNA and small antiviral compounds activate caspase‐1 through cryopyrin/Nalp3. Nature 2006; 440: 233 – 236.en_US
dc.identifier.citedreferenceEcker JA, Massire C, Hall TA, Ranken R, Pennella TT, Agasino IC, Blyn LB, Hofstadler SA, Endy TP, Scott PT, Lindler L, Hamilton T, Gaddy C, Snow K, Pe M, Fishbain J, Craft D, Deye G, Riddell S, Milstrey E, Petruccelli B, Brisse S, Harpin V, Schink A, Ecker DJ, Sampath R, Eshoo MW: Identification of Acinetobacter species and genotyping of Acinetobacter baumannii by multilocus PCR and mass spectrometry. J Clin Microbiol 2006; 44: 2921 – 2932.en_US
dc.identifier.citedreferenceLegoff J, Feghoul L, Mercier‐Delarue S, Dalle JH, Scieux C, Cherot J, Sicre de Fontbrune F, Baruchel A, Socie G, Simon F: Broad‐Range PCR/electrospray ionization mass spectrometry for detection and typing of adenovirus and other opportunistic viruses in stem cell transplant patients. J Clin Microbiol 2013; 51: 4186 – 4192.en_US
dc.identifier.citedreferenceRomero R, Yoon BH, Kenney JS, Gomez R, Allison AC, Sehgal PB: Amniotic fluid interleukin‐6 determinations are of diagnostic and prognostic value in preterm labor. Am J Reprod Immunol 1993; 30: 167 – 183.en_US
dc.identifier.citedreferenceRomero R, Yoon BH, Mazor M, Gomez R, Diamond MP, Kenney JS, Ramirez M, Fidel PL, Sorokin Y, Cotton D, Sehgal P: The diagnostic and prognostic value of amniotic fluid white blood cell count, glucose, interleukin‐6, and gram stain in patients with preterm labor and intact membranes. Am J Obstet Gynecol 1993; 169: 805 – 816.en_US
dc.identifier.citedreferenceAndrews WW, Hauth JC, Goldenberg RL, Gomez R, Romero R, Cassell GH: Amniotic fluid interleukin‐6: correlation with upper genital tract microbial colonization and gestational age in women delivered after spontaneous labor versus indicated delivery. Am J Obstet Gynecol 1995; 173: 606 – 612.en_US
dc.identifier.citedreferenceBianchi ME, Manfredi AA: Immunology. Dangers in and out. Science 2009; 323: 1683 – 1684.en_US
dc.identifier.citedreferenceYoon BH, Romero R, Park JS, Chang JW, Kim YA, Kim JC, Kim KS: Microbial invasion of the amniotic cavity with Ureaplasma urealyticum is associated with a robust host response in fetal, amniotic, and maternal compartments. Am J Obstet Gynecol 1998; 179: 1254 – 1260.en_US
dc.identifier.citedreferenceMaymon E, Romero R, Chaiworapongsa T, Berman S, Conoscenti G, Gomez R, Edwin S: Amniotic fluid matrix metalloproteinase‐8 in preterm labor with intact membranes. Am J Obstet Gynecol 2001; 185: 1149 – 1155.en_US
dc.identifier.citedreferenceCobo T, Palacio M, Martinez‐Terron M, Navarro‐Sastre A, Bosch J, Filella X, Gratacos E: Clinical and inflammatory markers in amniotic fluid as predictors of adverse outcomes in preterm premature rupture of membranes. Am J Obstet Gynecol 2011; 205: 126 e121 – 126 e128.en_US
dc.identifier.citedreferenceCobo T, Kacerovsky M, Holst RM, Hougaard DM, Skogstrand K, Wennerholm UB, Hagberg H, Jacobsson B: Intra‐amniotic inflammation predicts microbial invasion of the amniotic cavity but not spontaneous preterm delivery in preterm prelabor membrane rupture. Acta Obstet Gynecol Scand 2012; 91: 930 – 935.en_US
dc.identifier.citedreferenceJacobsson B, Holst RM, Wennerholm UB, Andersson B, Lilja H, Hagberg H: Monocyte chemotactic protein‐1 in cervical and amniotic fluid: relationship to microbial invasion of the amniotic cavity, intra‐amniotic inflammation, and preterm delivery. Am J Obstet Gynecol 2003; 189: 1161 – 1167.en_US
dc.identifier.citedreferenceSoto E, Espinoza J, Nien JK, Kusanovic JP, Erez O, Richani K, Santolaya‐Forgas J, Romero R: Human beta‐defensin‐2: a natural antimicrobial peptide present in amniotic fluid participates in the host response to microbial invasion of the amniotic cavity. J Matern Fetal Neonatal Med 2007; 20: 15 – 22.en_US
dc.identifier.citedreferenceBennett P, Fisk N: Chorioamnionitis and pre‐term delivery. Baillieres Clin Obstet Gynaecol 1993; 7: 25 – 43.en_US
dc.identifier.citedreferenceJacobsson B, Mattsby‐Baltzer I, Hagberg H: Interleukin‐6 and interleukin‐8 in cervical and amniotic fluid: relationship to microbial invasion of the chorioamniotic membranes. BJOG 2005; 112: 719 – 724.en_US
dc.identifier.citedreferenceMiralles R, Hodge R, McParland PC, Field DJ, Bell SC, Taylor DJ, Grant WD, Kotecha S: Relationship between antenatal inflammation and antenatal infection identified by detection of microbial genes by polymerase chain reaction. Pediatr Res 2005; 57: 570 – 577.en_US
dc.identifier.citedreferenceLee SE, Romero R, Kim CJ, Shim SS, Yoon BH: Funisitis in term pregnancy is associated with microbial invasion of the amniotic cavity and intra‐amniotic inflammation. J Matern Fetal Neonatal Med 2006; 19: 693 – 697.en_US
dc.identifier.citedreferenceHecht JL, Onderdonk A, Delaney M, Allred EN, Kliman HJ, Zambrano E, Pflueger SM, Livasy CA, Bhan I, Leviton A: Characterization of chorioamnionitis in 2nd‐trimester C‐section placentas and correlation with microorganism recovery from subamniotic tissues. Pediatr Dev Pathol 2008; 11: 15 – 22.en_US
dc.identifier.citedreferenceDiGiulio DB, Romero R, Amogan HP, Kusanovic JP, Bik EM, Gotsch F, Kim CJ, Erez O, Edwin S, Relman DA: Microbial prevalence, diversity and abundance in amniotic fluid during preterm labor: a molecular and culture‐based investigation. PLoS ONE 2008; 3: e3056.en_US
dc.identifier.citedreferenceKim MJ, Romero R, Gervasi MT, Kim JS, Yoo W, Lee DC, Mittal P, Erez O, Kusanovic JP, Hassan SS, Kim CJ: Widespread microbial invasion of the chorioamniotic membranes is a consequence and not a cause of intra‐amniotic infection. Lab Invest 2009; 89: 924 – 936.en_US
dc.identifier.citedreferenceKacerovsky M, Pliskova L, Bolehovska R, Musilova I, Hornychova H, Tambor V, Jacobsson B: The microbial load with genital mycoplasmas correlates with the degree of histologic chorioamnionitis in preterm PROM. Am J Obstet Gynecol 2011; 205: 213 e211 – 213 e217.en_US
dc.identifier.citedreferenceChen ML, Allred EN, Hecht JL, Onderdonk A, VanderVeen D, Wallace DK, Leviton A, Dammann O: Placenta microbiology and histology and the risk for severe retinopathy of prematurity. Invest Ophthalmol Vis Sci 2011; 52: 7052 – 7058.en_US
dc.identifier.citedreferenceRedline RW: Inflammatory response in acute chorioamnionitis. Semin Fetal Neonatal Med 2012; 17: 20 – 25.en_US
dc.identifier.citedreferenceRomero R, Salafia CM, Athanassiadis AP, Hanaoka S, Mazor M, Sepulveda W, Bracken MB: The relationship between acute inflammatory lesions of the preterm placenta and amniotic fluid microbiology. Am J Obstet Gynecol 1992; 166: 1382 – 1388.en_US
dc.identifier.citedreferenceOppenheim JJ, Yang D: Alarmins: chemotactic activators of immune responses. Curr Opin Immunol 2005; 17: 359 – 365.en_US
dc.identifier.citedreferenceHuang H, Evankovich J, Yan W, Nace G, Zhang L, Ross M, Liao X, Billiar T, Xu J, Esmon CT, Tsung A: Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll‐like receptor 9 in mice. Hepatology 2011; 54: 999 – 1008.en_US
dc.identifier.citedreferenceCardenas I, Means RE, Aldo P, Koga K, Lang SM, Booth CJ, Manzur A, Oyarzun E, Romero R, Mor G: Viral infection of the placenta leads to fetal inflammation and sensitization to bacterial products predisposing to preterm labor. J Immunol 2010; 185: 1248 – 1257.en_US
dc.identifier.citedreferenceMor G, Cardenas I: The immune system in pregnancy: a unique complexity. Am J Reprod Immunol 2010; 63: 425 – 433.en_US
dc.identifier.citedreferenceIlievski V, Hirsch E: Synergy between viral and bacterial toll‐like receptors leads to amplification of inflammatory responses and preterm labor in the mouse. Biol Reprod 2010; 83: 767 – 773.en_US
dc.identifier.citedreferenceCardenas I, Mor G, Aldo P, Lang SM, Stabach P, Sharp A, Romero R, Mazaki‐Tovi S, Gervasi M, Means RE: Placental viral infection sensitizes to endotoxin‐induced pre‐term labor: a double hit hypothesis. Am J Reprod Immunol 2011; 65: 110 – 117.en_US
dc.identifier.citedreferenceRacicot K, Cardenas I, Wunsche V, Aldo P, Guller S, Means RE, Romero R, Mor G: Viral infection of the pregnant cervix predisposes to ascending bacterial infection. J Immunol 2013; 191: 934 – 941.en_US
dc.identifier.citedreferenceJaneway CA Jr, Medzhitov R: Innate immune recognition. Annu Rev Immunol 2002; 20: 197 – 216.en_US
dc.identifier.citedreferenceNathan C: Points of control in inflammation. Nature 2002; 420: 846 – 852.en_US
dc.identifier.citedreferenceSerhan CN, Chiang N, Van Dyke TE: Resolving inflammation: dual anti‐inflammatory and pro‐resolution lipid mediators. Nat Rev Immunol 2008; 8: 349 – 361.en_US
dc.identifier.citedreferenceMedzhitov R: Origin and physiological roles of inflammation. Nature 2008; 454: 428 – 435.en_US
dc.identifier.citedreferenceMedzhitov R: Inflammation 2010: new adventures of an old flame. Cell 2010; 140: 771 – 776.en_US
dc.identifier.citedreferenceMatzinger P: Tolerance, danger, and the extended family. Annu Rev Immunol 1994; 12: 991 – 1045.en_US
dc.identifier.citedreferenceMedzhitov R, Preston‐Hurlburt P, Janeway CA Jr: A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997; 388: 394 – 397.en_US
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