View Item 

Show simple item record

Gender‐specific Issues in Traumatic Injury and Resuscitation: Consensus‐based Recommendations for Future Research

dc.contributor.authorSethuraman, Kinjal N.en_US
dc.contributor.authorMarcolini, Evie G.en_US
dc.contributor.authorMcCunn, Maureenen_US
dc.contributor.authorHansoti, Bhaktien_US
dc.contributor.authorVaca, Federico E.en_US
dc.contributor.authorNapolitano, Lena M.en_US
dc.date.accessioned2015-01-07T15:24:43Z
dc.date.availableWITHHELD_12_MONTHSen_US
dc.date.available2015-01-07T15:24:43Z
dc.date.issued2014-12en_US
dc.identifier.citationSethuraman, Kinjal N.; Marcolini, Evie G.; McCunn, Maureen; Hansoti, Bhakti; Vaca, Federico E.; Napolitano, Lena M. (2014). "Gender‐specific Issues in Traumatic Injury and Resuscitation: Consensus‐based Recommendations for Future Research." Academic Emergency Medicine 21(12): 1386-1394.en_US
dc.identifier.issn1069-6563en_US
dc.identifier.issn1553-2712en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/110065
dc.description.abstractTraumatic injury remains an unacceptably high contributor to morbidity and mortality rates across the United States. Gender‐specific research in trauma and emergency resuscitation has become a rising priority. In concert with the 2014 Academic Emergency Medicine consensus conference “Gender‐specific Research in Emergency Care: Investigate, Understand, and Translate How Gender Affects Patient Outcomes,” a consensus‐building group consisting of experts in emergency medicine, critical care, traumatology, anesthesiology, and public health convened to generate research recommendations and priority questions to be answered and thus move the field forward. Nominal group technique was used for the consensus‐building process and a combination of face‐to‐face meetings, monthly conference calls, e‐mail discussions, and preconference surveys were used to refine the research questions. The resulting research agenda focuses on opportunities to improve patient outcomes by expanding research in sex‐ and gender‐specific emergency care in the field of traumatic injury and resuscitation.en_US
dc.publisherWiley Periodicals, Inc.en_US
dc.publisherSociety for Academic Emergency Medicine, Philadelphiaen_US
dc.titleGender‐specific Issues in Traumatic Injury and Resuscitation: Consensus‐based Recommendations for Future Researchen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/110065/1/acem12536.pdf
dc.identifier.doi10.1111/acem.12536en_US
dc.identifier.sourceAcademic Emergency Medicineen_US
dc.identifier.citedreferenceHolbrook TL, Hoyt DB, Stein MB, Sieber WJ. Gender differences in long‐term posttraumatic stress disorder outcomes after major trauma: women are at higher risk of adverse outcomes than men. J Trauma 2002; 53: 882 – 8.en_US
dc.identifier.citedreferenceHolbrook TL, Hoyt DB, Anderson JP. The importance of gender on outcome after major trauma: functional and psychologic outcomes in women versus men. J Trauma 2001; 50: 270 – 3.en_US
dc.identifier.citedreferenceHolbrook TL, Hoyt DB. The impact of major trauma: quality‐of‐life outcomes are worse in women than in men, independent of mechanism and injury severity. J Trauma 2004; 56: 284 – 90.en_US
dc.identifier.citedreferenceAxinn WG, Ghimire DJ, Williams NE, Scott KM. Gender, traumatic events, and mental health disorders in a rural Asian setting. J Health Soc Behavior 2013; 54: 444 – 61.en_US
dc.identifier.citedreferenceOsborn TM, Tracy JK, Dunne JR, Pasquale M, Napolitano LM. Epidemiology of sepsis in patients with traumatic injury. Crit Care Med 2004; 32: 2234 – 40.en_US
dc.identifier.citedreferenceGannon CJ, Pasquale M, Tracy JK, McCarter RJ, Napolitano LM. Male gender is associated with increased risk for postinjury pneumonia. Shock 2004; 21: 410 – 4.en_US
dc.identifier.citedreferenceSchoeneberg C, Kauther MD, Hussmann B, Keitel J, Schmitz D, Lendemans S. Gender‐specific differences in severely injured patients between 2002 and 2011: data analysis with matched‐pair analysis. Crit Care 2013; 17: R277.en_US
dc.identifier.citedreferenceFrink M, Pape HC, van Griensven M, Krettek C, Chaudry IH, Hildebrand F. Influence of sex and age on MODS and cytokines after multiple injuries. Shock 2007; 27: 151 – 6.en_US
dc.identifier.citedreferenceHeffernan DS, Dossett LA, Lightfoot MA, et al. Gender and acute respiratory distress syndrome in critically injured adults: a prospective study. J Trauma 2011; 71: 878 – 85.en_US
dc.identifier.citedreferenceCroce MA, Brasel KJ, Coimbra R, et al. National Trauma Institute prospective evaluation of the ventilator bundle in trauma patients: does it really work? J Trauma Acute Care Surg 2013; 74: 354 – 62.en_US
dc.identifier.citedreferenceMohr AM, Lavery RF, Sifri ZC, et al. Gender differences in glucose variability after severe trauma. Am Surg 2010; 76: 896 – 902.en_US
dc.identifier.citedreferenceHouston‐Bolze MS, Downing MT, Sayed AM, Meserve LA. Gender differences in the responses of serum insulin‐like growth factor‐1 and transthyretin (prealbumin) to trauma. Crit Care Med 1996; 24: 1982 – 7.en_US
dc.identifier.citedreferenceHouston‐Bolze MS, Downing MT, Sayed AM, Williford JH. Serum insulin‐like growth factor binding protein‐3 responds differently to trauma in men and women. Crit Care Med 1996; 24: 1988 – 92.en_US
dc.identifier.citedreferenceRatcliff JJ, Greenspan AI, Goldstein FC, et al. Gender and traumatic brain injury: do the sexes fare differently? Brain Inj 2007; 21: 1023 – 30.en_US
dc.identifier.citedreferenceNeimeier JP, Marwitz JH, Lesher K, Walker WC, Bushnik T. Gender differences in executive functions following traumatic brain injury. Neuropsychol Rehab 2007; 17: 293 – 313.en_US
dc.identifier.citedreferenceColantonio A, Harris JE, Ratcliff G, Chase S, Ellis K. Gender differences in self reported long term outcomes following moderate to severer traumatic brain injury. BMC Neurol 2010; 10: 102.en_US
dc.identifier.citedreferenceBlasius AL, Beutler B. Intracellular Toll‐like receptors. Immunity 2010; 32: 305 – 15.en_US
dc.identifier.citedreferenceToubiana J, Courtine E, Pène F, et al. IRAK1 functional genetic variant affects severity of septic shock. Crit Care Med 2010; 38: 2287 – 94.en_US
dc.identifier.citedreferenceArcaroli J, Silva E, Maloney JP, et al. Variant IRAK‐1 haplotype is associated with increased nuclear factor‐kappaB activation and worse outcomes in sepsis. Am J Respir Crit Care Med 2006; 173: 1335 – 41.en_US
dc.identifier.citedreferenceSperry J, Zuckerbraun B, Zolin S, et al. X‐Chromosome Linked IRAK1 Polymorphism Is Strong Predictor of Multiple Organ Failure and Mortality Post‐injury. Presented at the 134th Annual Meeting of the American Surgical Association, Boston, April 10?12, 2014.en_US
dc.identifier.citedreferenceCenters for Disease Control and Prevention, National Center for Injury Prevention and Control. Web‐based Injury Statistics Query and Reporting System (WISQARS). Available at: http://www.cdc.gov/injury/wisqars/. Accessed Sep 23, 2014.en_US
dc.identifier.citedreferenceMcGregor AJ, Greenberg M, Safdar B, et al. Focusing a gender lens on emergency medicine research: 2012 update. Acad Emerg Med 2013; 20: 313 – 20.en_US
dc.identifier.citedreferenceFarace E, Alves WM. Do women fare worse: a metaanalysis of gender differences in traumatic brain injury outcome. J Neurosurg 2000; 93: 539 – 45.en_US
dc.identifier.citedreferenceMacKenzie EJ, Rivara FP, Jurkovich GJ, et al. A national evaluation of the effect of trauma‐center care on mortality. N Engl J Med 2006; 354: 366 – 78.en_US
dc.identifier.citedreferenceHaas B, Stukel TA, Gomez D, et al. The mortality benefit of direct trauma center transport in a regional trauma system: a population‐based analysis. J Trauma Acute Care Surg 2012; 72: 1510 – 7.en_US
dc.identifier.citedreferenceGarwe T, Cowan LD, Neas B, Cathey T, Danford BC, Greenawalt P. Survival benefit of transfer to tertiary trauma centers for major trauma patients initially presenting to nontertiary trauma centers. Acad Emerg Med 2010; 17: 1223 – 32.en_US
dc.identifier.citedreferenceGomez D, Haas B, de Mestral C, et al. Gender‐associated differences in access to trauma center care: a population‐based analysis. Surgery 2012; 152: 179 – 85.en_US
dc.identifier.citedreferenceKnaus W, Draper E, Wagner D, Zimmerman S. An evaluation of outcome from intensive care in major medical centers. Ann Intern Med 1986; 104: 410 – 8.en_US
dc.identifier.citedreferenceShortell SM, Zimmerman JE, Rousseau DM, et al. The performance of intensive care units: does good management make a difference? Med Care 1994; 32: 508 – 25.en_US
dc.identifier.citedreferenceSexton J, Thomas E, Helmreich RL. Error, stress and teamwork in medicine and aviation: cross sectional surveys. BMJ 2000; 320: 745 – 9.en_US
dc.identifier.citedreferenceMcCunn M, Paciotti B, Narayan M, Ziegert J, Barg FK. Leadership and Gender During Acute Trauma Resuscitation. Annual Scientific Meeting, Eastern Association for the Surgery of Trauma, Naples, Florida, January 2014.en_US
dc.identifier.citedreferenceEagly AH, Karau SJ. Role incongruity theory of prejudice toward female leaders. Psychol Rev 2002; 109: 573 – 98.en_US
dc.identifier.citedreferenceBartels C, Goetz S, Ward E, Carnes M. Internal medicine resident's perceived ability to direct patient care: impact of gender and experience. J Womens Health (Larchmnt) 2008; 17: 1615 – 21.en_US
dc.identifier.citedreferenceMcCunn M, Burchill C, Speck RM, Pascual J, Bohm E, Barg FP. Collaboration and Satisfaction of Trauma Team Members: Physicians and Males Are More Satisfied. Mid‐Atlantic Regional Meeting: Society for Academic Emergency Medicine, Philadelphia, March 2014.en_US
dc.identifier.citedreferenceYang KC, Zhou MJ, Sperry JL, et al. Significant sex‐based outcome differences in severely injured Chinese trauma patients. Shock 2014; 42: 11 – 5.en_US
dc.identifier.citedreferenceWohltmann CD, Franklin GA, Boaz PW, et al. A multicenter evaluation of whether gender dimorphism affects survival after trauma. Am J Surg 2001; 181: 297 – 300.en_US
dc.identifier.citedreferenceMagnotti LJ, Fischer PE, Zarzaur BL, Fabian TC, Croce MA. Impact of gender on outcomes after blunt injury: a definitive analysis of more than 36,000 trauma patients. J Am Coll Surg 2008; 206: 984 – 92.en_US
dc.identifier.citedreferenceRappold JF, Coimbra R, Hoyt DB, et al. Female gender does not protect blunt trauma patients from complications and mortality. J Trauma 2002; 53: 436 – 41.en_US
dc.identifier.citedreferenceBowles BJ, Roth B, Demetriades D. Sexual dimorphism in trauma? A retrospective evaluation of outcome. Injury 2003; 34: 27 – 31.en_US
dc.identifier.citedreferenceCoimbra R, Hoyt DB, Potenza BM, Fortlage D, Hollingsworth‐Fridlund P. Does sexual dimorphism influence outcome of traumatic brain injury patients? The answer is no!. J Trauma 2003; 54: 689 – 700.en_US
dc.identifier.citedreferenceGannon CJ, Napolitano LM, Pasquale M, Tracy JK, McCarter RJ. A statewide population‐based study of gender differences in trauma: validation of a prior single‐institution study. J Am Coll Surg 2002; 195: 11 – 8.en_US
dc.identifier.citedreferenceGeorge RL, McGwin G Jr, Metzger J, Chaudry IH, Rue LW 3rd. The association between gender and mortality among trauma patients as modified by age. J Trauma 2003; 54: 464 – 71.en_US
dc.identifier.citedreferenceNapolitano LM, Greco ME, Rodriguez A, Kufera JA, West RS, Scalea TM. Gender differences in adverse outcomes after blunt trauma. J Trauma 2001; 50: 274 – 80.en_US
dc.identifier.citedreferenceHaider AH, Crompton JG, Oyetunji T, et al. Females have fewer complications and lower mortality following trauma than similarly injured males: a risk adjusted analysis of adults in the National Trauma Data Bank. Surgery 2009; 146: 308 – 15.en_US
dc.identifier.citedreferenceSperry JL, Nathens AB, Frankel HL, et al. Characterization of the gender dimorphism after injury and hemorrhagic shock: are hormonal differences responsible? Crit Care Med 2008; 36: 1838 – 45.en_US
dc.identifier.citedreferenceHaider AH, Crompton JG, Chang DC, et al. Evidence of hormonal basis for improved survival among females with trauma‐associated shock: an analysis of the National Trauma Data Bank. J Trauma 2010; 69: 537 – 40.en_US
dc.identifier.citedreferenceGuidry CA, Swenson BR, Davies SW, et al. Sex‐ and diagnosis‐dependent differences in mortality and admission cytokine levels among patients admitted for intensive care. Crit Care Med 2014; 42: 1110 – 20.en_US
dc.identifier.citedreferenceKerby JD, McGwin G Jr, George RL, Cross JA, Chaudry IH, Rue LW 3rd. Sex differences in mortality after burn injury: results of analysis of the National Burn Repository of the American Burn Association. J Burn Care Res 2006; 27: 452 – 6.en_US
dc.identifier.citedreferenceGeorge RL, McGwin G Jr, Schwacha MG, et al. The association between sex and mortality among burn patients as modified by age. J Burn Care Rehabil 2005; 26: 416 – 21.en_US
dc.identifier.citedreferenceSummers JI, Ziembicki JA, Corcos AC, Peitzman AB, Billiar TR, Sperry JL. Characterization of the sex dimorphism following severe thermal injury. J Burn Care Res 2014; [Epub ahead of print].en_US
dc.identifier.citedreferenceGale SC, Sicoutris C, Reilly PM, Schwab CW, Gracias VH. Poor glycemic control is associated with increased mortality in critically ill trauma patients. Am Surg 2007; 73: 454 – 60.en_US
dc.identifier.citedreferenceSperry JL, Vodovotz Y, Ferrell RE, et al. Racial disparities and sex‐based outcomes differences after severe injury. J Am Coll Surg 2012; 214: 973 – 80.en_US
dc.identifier.citedreferenceGee AC, Sawai RS, Differding J, Muller P, Underwood S, Schreiber MA. The influence of sex hormones on coagulation and inflammation in the trauma patient. Shock 2008; 29: 334 – 41.en_US
dc.identifier.citedreferenceAngele MK, Faist E. Gender‐specific immune response following shock: clinical and experimental data. Eur J Trauma 2000; 26: 267 – 77.en_US
dc.identifier.citedreferenceDossett LA, Swenson BR, Heffernan D, et al. High levels of endogenous estrogens are associated with death in the critically injured adult. J Trauma 2008; 64: 580 – 5.en_US
dc.identifier.citedreferenceMay AK, Dossett LA, Norris PR, et al. Estradiol is associated with mortality in critically ill trauma and surgical patients. Crit Care Med 2008; 36: 62 – 8.en_US
dc.identifier.citedreferenceDeitch EA, Livingston DH, Lavery RF, Monaghan SF, Bongu A, Machiedo GW. Hormonally active women tolerate shock‐trauma better than do men: a prospective study of over 4000 trauma patients. Ann Surg 2007; 246: 447 – 55.en_US
dc.identifier.citedreferenceRowell SE, Barbosa RR, Allison CE, et al. Gender‐based differences in mortality in response to high product ratio massive transfusion. J Trauma 2011; 71 ( 2 suppl 3 ): S375 – 9.en_US
dc.identifier.citedreferenceAlspach JG. Is there gender bias in critical care? Crit Care Nurse 2012; 32: 8 – 14.en_US
dc.identifier.citedreferenceFowler RA, Filate W, Hartleib M, Frost DW, Lazongas C, Hladunewich M. Sex and critical illness. Curr Opin Crit Care 2009; 15: 442 – 9.en_US
dc.identifier.citedreferenceFowler RA, Sabur N, Li P, et al. Sex‐and age‐based differences in the delivery and outcomes of critical care. CMAJ 2007; 177: 1513 – 9.en_US
dc.identifier.citedreferenceRice TW, Morris S, Tortella BJ, Wheeler AP, Christensen MC. Deviations from evidence‐based clinical management guidelines increase mortality in critically injured trauma patients. Crit Care Med 2012; 40: 778 – 86.en_US
dc.identifier.citedreferenceNapolitano LM. Guideline compliance in trauma: evidence‐based protocols to improve trauma outcomes? Crit Care Med 2012; 40: 990 – 2.en_US
dc.identifier.citedreferenceGilliver SC. Sex steroids as inflammatory regulators. J Steroid Biochem Mol Biol 2010; 120: 105 – 15.en_US
dc.identifier.citedreferenceHagemo JS, Stanworth S, Juffermans NP, et al. Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study. Crit Care 2014; 18: R52.en_US
dc.identifier.citedreferenceWright DW, Kellermann AL, Hertzberg VS, et al. ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury. Ann Emerg Med 2007; 49: 391 – 402.en_US
dc.identifier.citedreferenceSpoerke N, Underwood S, Differding J, et al. Effects of ethanol intoxication and gender on blood coagulation. J Trauma 2010; 68: 1106 – 11.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
acem12536.pdf
Size:
318.7KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.