Haploinsufficiency of myostatin protects against aging‐related declines in muscle function and enhances the longevity of mice
dc.contributor.author | Mendias, Christopher L. | en_US |
dc.contributor.author | Bakhurin, Konstantin I. | en_US |
dc.contributor.author | Gumucio, Jonathan P. | en_US |
dc.contributor.author | Shallal‐ayzin, Mark V. | en_US |
dc.contributor.author | Davis, Carol S. | en_US |
dc.contributor.author | Faulkner, John A. | en_US |
dc.date.accessioned | 2015-08-05T16:47:10Z | |
dc.date.available | 2016-09-06T15:43:59Z | en |
dc.date.issued | 2015-08 | en_US |
dc.identifier.citation | Mendias, Christopher L.; Bakhurin, Konstantin I.; Gumucio, Jonathan P.; Shallal‐ayzin, Mark V. ; Davis, Carol S.; Faulkner, John A. (2015). "Haploinsufficiency of myostatin protects against agingâ related declines in muscle function and enhances the longevity of mice." Aging Cell 14(4): 704-706. | en_US |
dc.identifier.issn | 1474-9718 | en_US |
dc.identifier.issn | 1474-9726 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/112228 | |
dc.publisher | Wiley Periodicals, Inc. | en_US |
dc.subject.other | GDF‐8 | en_US |
dc.subject.other | myostatin | en_US |
dc.subject.other | muscle contractility | en_US |
dc.subject.other | muscle atrophy | en_US |
dc.subject.other | longevity | en_US |
dc.subject.other | skeletal muscle | en_US |
dc.subject.other | sarcopenia | en_US |
dc.title | Haploinsufficiency of myostatin protects against aging‐related declines in muscle function and enhances the longevity of mice | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/112228/1/acel12339-sup-0003-TableS1.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/112228/2/acel12339.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/112228/3/acel12339-sup-0004-TableS2.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/112228/4/acel12339-sup-0002-FigureS1.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/112228/5/acel12339-sup-0001-DataS1.pdf | |
dc.identifier.doi | 10.1111/acel.12339 | en_US |
dc.identifier.source | Aging Cell | en_US |
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dc.identifier.citedreference | Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Abellan van Kan G, Andrieu S, Bauer J, Breuille D, Cederholm T, Chandler J, De Meynard C, Donini L, Harris T, Kannt A, Keime Guibert F, Onder G, Papanicolaou D, Rolland Y, Rooks D, Sieber C, Souhami E, Verlaan S, Zamboni M ( 2011 ) Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J. Am. Med. Dir. Assoc. 12, 249 – 256. | en_US |
dc.identifier.citedreference | Brooks SV, Faulkner JA ( 1988 ) Contractile properties of skeletal muscles from young, adult and aged mice. J. Physiol. (Lond) 404, 71 – 82. | en_US |
dc.identifier.citedreference | Blagosklonny MV ( 2013 ) Big mice die young but large animals live longer. Aging (Albany NY) 5, 227 – 233. | en_US |
dc.identifier.citedreference | Ramaswamy KS, Palmer ML, Van der Meulen JH, Renoux A, Kostrominova TY, Michele DE, Faulkner JA ( 2011 ) Lateral transmission of force is impaired in skeletal muscles of dystrophic mice and very old rats. J. Physiol. (Lond) 589, 1195 – 1208. | en_US |
dc.identifier.citedreference | Miller MD, Crotty M, Giles LC, Bannerman E, Whitehead C, Cobiac L, Daniels LA, Andrews G ( 2002 ) Corrected arm muscle area: an independent predictor of long‐term mortality in community‐dwelling older adults? J. Am. Geriatr. Soc. 50, 1272 – 1277. | en_US |
dc.identifier.citedreference | Mendias CL, Bakhurin KI, Faulkner JA ( 2008 ) Tendons of myostatin‐deficient mice are small, brittle, and hypocellular. Proc. Natl Acad. Sci. USA 105, 388 – 393. | en_US |
dc.identifier.citedreference | Mendias CL, Marcin JE, Calerdon DR, Faulkner JA ( 2006 ) Contractile properties of EDL and soleus muscles of myostatin‐deficient mice. J. Appl. Physiol. 101, 898 – 905. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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