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Wnt3a: functions and implications in cancer

dc.contributor.authorHe, Sha
dc.contributor.authorLu, Yi
dc.contributor.authorLiu, Xia
dc.contributor.authorHuang, Xin
dc.contributor.authorKeller, Evan T
dc.contributor.authorQian, Chao-Nan
dc.contributor.authorZhang, Jian
dc.date.accessioned2015-09-14T18:02:10Z
dc.date.available2015-09-14T18:02:10Z
dc.date.issued2015-09-14
dc.identifier.citationChinese Journal of Cancer. 2015 Sep 14;34(3):50
dc.identifier.urihttps://hdl.handle.net/2027.42/113235en_US
dc.description.abstractAbstract Wnt3a, one of Wnt family members, plays key roles in regulating pleiotropic cellular functions, including self-renewal, proliferation, differentiation, and motility. Accumulating evidence has suggested that Wnt3a promotes or suppresses tumor progression via the canonical Wnt signaling pathway depending on cancer type. In addition, the roles of Wnt3a signaling can be inhibited by multiple proteins or chemicals. Herein, we summarize the latest findings on Wnt3a as an important therapeutic target in cancer.
dc.titleWnt3a: functions and implications in cancer
dc.typeArticleen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/113235/1/40880_2015_Article_52.pdf
dc.identifier.doi10.1186/s40880-015-0052-4en_US
dc.language.rfc3066en
dc.rights.holderHe et al.
dc.date.updated2015-09-14T18:02:12Z
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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