The Effect of Additives on the Behavior of Phase Sensitive In Situ Forming Implants
dc.contributor.author | Solorio, Luis | en_US |
dc.contributor.author | Sundarapandiyan, Divya | en_US |
dc.contributor.author | Olear, Alex | en_US |
dc.contributor.author | Exner, Agata A. | en_US |
dc.date.accessioned | 2015-10-07T20:42:58Z | |
dc.date.available | 2016-12-01T14:33:06Z | en |
dc.date.issued | 2015-10 | en_US |
dc.identifier.citation | Solorio, Luis; Sundarapandiyan, Divya; Olear, Alex; Exner, Agata A. (2015). "The Effect of Additives on the Behavior of Phase Sensitive In Situ Forming Implants." Journal of Pharmaceutical Sciences 104(10): 3471-3480. | en_US |
dc.identifier.issn | 0022-3549 | en_US |
dc.identifier.issn | 1520-6017 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/113738 | |
dc.publisher | Nova Science Publishers, Inc | en_US |
dc.publisher | Wiley Periodicals, Inc. | en_US |
dc.subject.other | Ultrasound | en_US |
dc.subject.other | Image analysis | en_US |
dc.subject.other | Phase transition | en_US |
dc.subject.other | Biomaterials | en_US |
dc.subject.other | Casting | en_US |
dc.subject.other | Controlled release | en_US |
dc.subject.other | Drug delivery systems | en_US |
dc.subject.other | Encapsulation | en_US |
dc.subject.other | Excipients | en_US |
dc.subject.other | Injectables | en_US |
dc.title | The Effect of Additives on the Behavior of Phase Sensitive In Situ Forming Implants | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/113738/1/jps24558.pdf | |
dc.identifier.doi | 10.1002/jps.24558 | en_US |
dc.identifier.source | Journal of Pharmaceutical Sciences | en_US |
dc.identifier.citedreference | Gopferich A. 1997. Polymer bulk erosion. Macromolecules 30 ( 9 ): 2598 – 2604. | en_US |
dc.identifier.citedreference | Astaneh R, Erfan M, Barzin J, Mobedi H, Moghimi H. 2008. Effects of ethyl benzoate on performance, morphology, and erosion of PLGA implants formed in situ. Adv Polym Technol 27 ( 1 ): 17 – 26. | en_US |
dc.identifier.citedreference | Liu QF, Zhang H, Zhou GC, Xie SB, Zou H, Yu YA, Li GD, Sun DX, Zhang GQ, Lu Y, Zhong YQ. 2010. In vitro and in vivo study of thymosin alpha1 biodegradable in situ forming poly(lactide‐co‐glycolide) implants. Int J Pharm 397 ( 1–2 ): 122 – 129. | en_US |
dc.identifier.citedreference | Astaneh R, Erfan M, Mobedi H, Moghimi HR. 2004. Formulation of an injectable implant for peptide delivery and studying the effect of polymer molecular weight on its release behavior. J Pept Sci 10: 142 – 142. | en_US |
dc.identifier.citedreference | Liu H, Venkatraman SS. 2012. Effect of polymer type on the dynamics of phase inversion and drug release in injectable in situ gelling systems. J Biomater Sci Polym Ed 23 ( 1–4 ): 251 – 266. | en_US |
dc.identifier.citedreference | Liu H, Venkatraman SS. 2014. Solid/hollow depots for drug delivery, part 1: Effect of drug characteristics and polymer molecular weight on the phase‐inversion dynamics, depot morphology, and drug release. J Pharm Sci 103 ( 2 ): 485 – 495. | en_US |
dc.identifier.citedreference | Liu Y, Kemmer A, Keim K, Curdy C, Petersen H, Kissel T. 2010. Poly(ethylene carbonate) as a surface‐eroding biomaterial for in situ forming parenteral drug delivery systems: A feasibility study. Eur J Pharm Biopharm 76 ( 2 ): 222 – 229. | en_US |
dc.identifier.citedreference | Patel RB, Carlson AN, Solorio L, Exner AA. 2010. Characterization of formulation parameters affecting low molecular weight drug release from in situ forming drug delivery systems. J Biomed Mater Res Part A 94A ( 2 ): 476 – 484. | en_US |
dc.identifier.citedreference | DesNoyer JR, McHugh AJ. 2003. The effect of pluronic on the protein release kinetics of an injectable drug delivery system. J Control Release 86 ( 1 ): 15 – 24. | en_US |
dc.identifier.citedreference | Sakai M, Imai T, Ohtake H, Azuma H, Otagiri M. 1997. Effects of absorption enhancers on the transport of model compounds in C aco‐2 cell monolayers: Assessment by confocal laser scanning microscopy. J Pharm Sci 86 ( 7 ): 779 – 785. | en_US |
dc.identifier.citedreference | Patel RB, Solorio L, Wu HP, Krupka T, Exner AA. 2010. Effect of injection site on in situ implant formation and drug release in vivo. J Control Release 147 ( 3 ): 350 – 358. | en_US |
dc.identifier.citedreference | Barton BF, Reeve JL, McHugh AJ. 1997. Observations on the dynamics of nonsolvent‐induced phase inversion. J Polym Sci Part B 35 ( 4 ): 569 – 585. | en_US |
dc.identifier.citedreference | Tang Y, Singh J. 2008. Controlled delivery of aspirin: Effect of aspirin on polymer degradation and in vitro release from PLGA based phase sensitive systems. Int J Pharm 357 ( 1–2 ): 119 – 125. | en_US |
dc.identifier.citedreference | Sweetman SC. 2011. Martindale: The complete drug reference. 37 ed. London, UK: Pharmaceutical Press, pp 4142. | en_US |
dc.identifier.citedreference | Gopferich A, Langer R. 1993. Modeling of polymer erosion. Macromolecules 26 ( 16 ): 4105 – 4112. | en_US |
dc.identifier.citedreference | Leuenberger H, Rohera BD, Haas C. 1987. Percolation theory—A novel‐approach to solid dosage form design. Int J Pharm 38 ( 1–3 ): 109 – 115. | en_US |
dc.identifier.citedreference | Alexis F. 2005. Factors affecting the degradation and drug‐release mechanism of poly(lactic acid) and poly[(lactic acid)‐co‐(glycolic acid)]. Polym Int 54 ( 1 ): 36 – 46. | en_US |
dc.identifier.citedreference | Li S, Vert M. 1996. Hydrolytic degradation of the coral/poly(DL‐lactic acid) bioresorbable material. J Biomater Sci Polym Ed 7 ( 9 ): 817 – 827. | en_US |
dc.identifier.citedreference | von Burkersroda F, Schedl L, Gopferich A. 2002. Why degradable polymers undergo surface erosion or bulk erosion. Biomaterials 23 ( 21 ): 4221 – 4231. | en_US |
dc.identifier.citedreference | Schadlich A, Kempe S, Mader K. 2014. Non‐invasive in vivo characterization of microclimate p H inside in situ forming PLGA implants using multispectral fluorescence imaging. J Control Release 179: 52 – 62. | en_US |
dc.identifier.citedreference | Brodbeck KJ, DesNoyer JR, McHugh AJ. 1999. Phase inversion dynamics of PLGA solutions related to drug delivery—Part II. The role of solution thermodynamics and bath‐side mass transfer. J Control Release 62 ( 3 ): 333 – 344. | en_US |
dc.identifier.citedreference | Zare M, Mobedi H, Barzin J, Mivehchi H, Jamshidi A, Mashayekhi R. 2008. Effect of additives on release profile of leuprolide acetate in an in situ forming controlled‐release system: In vitro study. J Appl Polym Sci 107 ( 6 ): 3781 – 3787. | en_US |
dc.identifier.citedreference | Wang LW, Kleiner L, Venkatraman S. 2003. Structure formation in injectable poly(lactide‐co‐glycolide) depots. J Control Release 90 ( 3 ): 345 – 354. | en_US |
dc.identifier.citedreference | Dhawan S, Kapil R, Kapoor DN, Kumar M. 2009. Development and evaluation of in situ gel forming system for sustained delivery of cyclosporine. Curr Drug Deliv 6 ( 5 ): 495 – 504. | en_US |
dc.identifier.citedreference | Kang FR, Singh J. 2005. In vitro release of insulin and biocompatibility of in situ forming gel systems. Int J Pharm 304 ( 1–2 ): 83 – 90. | en_US |
dc.identifier.citedreference | Prabhu S, Tran LP, Betageri GV. 2005. Effect of co‐solvents on the controlled release of calcitonin polypeptide from in situ biodegradable polymer implants. Drug Deliv 12 ( 6 ): 393 – 398. | en_US |
dc.identifier.citedreference | Wang L, Venkatraman S, Kleiner L. 2004. Drug release from injectable depots: Two different in vitro mechanisms. J Control Release 99 ( 2 ): 207 – 216. | en_US |
dc.identifier.citedreference | Yapar A, Baykara T. 2010. Effects of solvent combinations on drug release from injectable phase sensitive liquid implants. Turk J Pharm Sci 7 ( 1 ): 49 – 56. | en_US |
dc.identifier.citedreference | Boom RM, Wienk IM, Vandenboomgaard T, Smolders CA. 1992. Microstructures in phase inversion membranes.2. The role of a polymeric additive. J Membr Sci 73 ( 2–3 ): 277 – 292. | en_US |
dc.identifier.citedreference | Dunn RL, English JP, Cowsar DR, Vanderbilt DP. 1999. Biodegradable in situ forming implants and methods of producing the same. Patent US 5990194 A. | en_US |
dc.identifier.citedreference | Dunn RL, Tipton AJ. 1997. Polymeric compositions useful as controlled release implants. Patent US 5702716 A. | en_US |
dc.identifier.citedreference | Ravivarapu HB, Moyer KL, Dunn RL. 2000. Sustained suppression of pituitary‐gonadal axis with an injectable, in situ forming implant of leuprolide acetate. J Pharm Sci 89 ( 6 ): 732 – 741. | en_US |
dc.identifier.citedreference | Smolders CA, Reuvers AJ, Boom RM, Wienk IM. 1992. Microstructures in phase‐inversion membranes. 1. Formation of macrovoids. J Membr Sci 73 ( 2–3 ): 259 – 275. | en_US |
dc.identifier.citedreference | Solorio L, Solorio LD, Gleeson S, Olear AM, Carlson AC, Exner AA. 2011. Phase inverting polymer systems in drug delivery and medicine. In Polymer phase behavior; Ehlers TP, Wilhelm JK,1 Ed. Hauppauge, New York: Nova Science Publishers, Inc. | en_US |
dc.identifier.citedreference | Vogrin N, Stropnik C, Musil V, Brumen M. 2002. The wet phase separation: The effect of cast solution thickness on the appearance of macrovoids in the membrane forming ternary cellulose acetate/acetone/water system. J Membr Sci 207 ( 1 ): 139 – 141. | en_US |
dc.identifier.citedreference | McHugh AJ. 2005. The role of polymer membrane formation in sustained release drug delivery systems. J Control Release 109 ( 1–3 ): 211 – 221. | en_US |
dc.identifier.citedreference | Brodbeck KJ, Graham PD, McHugh AJ. 1999. Phase inversion dynamics of PLGA solutions related to drug delivery. J Control Release 58(2): 233 – 245. | en_US |
dc.identifier.citedreference | Mchugh AJ, Miller DC. 1995. The dynamics of diffusion and gel growth during nonsolvent‐induced phase inversion of polyethersulfone. J Membr Sci 105 ( 1–2 ): 121 – 136. | en_US |
dc.identifier.citedreference | Mchugh AJ, Tsay CS. 1992. Dynamics of the phase inversion process. J Appl Polym Sci 46 ( 11 ): 2011 – 2021. | en_US |
dc.identifier.citedreference | Exner AA, Saidel GM. 2008. Drug‐eluting polymer implants in cancer therapy. Expert Opin Drug Deliv 5 ( 7 ): 775 – 788. | en_US |
dc.identifier.citedreference | Dunn RL, Garrett S. 1998. The drug delivery and biomaterial attributes of the ATRIGEL technology in the treatment of periodontal disease. Expert Opin Invest Drugs 7 ( 9 ): 1483 – 1491. | en_US |
dc.identifier.citedreference | Solorio L, Olear AM, Zhou H, Beiswenger AC, Exner AA. 2012. Effect of cargo properties on in situ forming implant behavior determined by noninvasive ultrasound imaging. Drug Deliv Transl Res 2 ( 1 ): 45 – 55. | en_US |
dc.identifier.citedreference | Kempe S, Metz H, Mader K. 2008. Do in situ forming PLG / NMP implants behave similar in vitro and in vivo? A non‐invasive and quantitative EPR investigation on the mechanisms of the implant formation process. J Control Release 130 ( 3 ): 220 – 225. | en_US |
dc.identifier.citedreference | Kempe S, Metz H, Pereira PGC, Mader K. 2010. Non‐invasive in vivo evaluation of in situ forming PLGA implants by benchtop magnetic resonance imaging ( BT ‐ MRI ) and EPR spectroscopy. Eur J Pharm Biopharm 74 ( 1 ): 102 – 108. | en_US |
dc.identifier.citedreference | Solorio L, Babin BM, Patel RB, Mach J, Azar N, Exner AA. 2010. Noninvasive characterization of in situ forming implants using diagnostic ultrasound. J Control Release 143 ( 2 ): 183 – 190. | en_US |
dc.identifier.citedreference | Tsay CS, Mchugh AJ. 1992. A technique for rapid measurement of diffusion‐coefficients. Ind Eng Chem Res 31 ( 1 ): 449 – 452. | en_US |
dc.identifier.citedreference | Solorio L, Olear AM, Hamilton JI, Patel RB, Beiswenger AC, Wallace JE, Zhou H, Exner AA. 2012. Noninvasive characterization of the effect of varying PLGA molecular weight blends on in situ forming implant behavior using ultrasound imaging. Theranostics 2 ( 11 ): 1064 – 1077. | en_US |
dc.identifier.citedreference | Astaneh R, Erfan M, Moghimi H, Mobedi H. 2009. Changes in morphology of in situ forming PLGA implant prepared by different polymer molecular weight and its effect on release behavior. J Pharm Sci 98 ( 1 ): 135 – 145. | en_US |
dc.identifier.citedreference | Brodbeck KJ, DesNoyer JR, McHugh AJ. 1999. Phase inversion dynamics of PLGA solutions related to drug delivery. Part II. The role of solution thermodynamics and bath‐side mass transfer. J Control Release 62 ( 3 ): 333 – 344. | en_US |
dc.identifier.citedreference | DesNoyer JR, McHugh AJ. 2001. Role of crystallization in the phase inversion dynamics and protein release kinetics of injectable drug delivery systems. J Control Release 70 ( 3 ): 285 – 294. | en_US |
dc.identifier.citedreference | Graham PD, Brodbeck KJ, McHugh AJ. 1999. Phase inversion dynamics of PLGA solutions related to drug delivery. J Control Release 58 ( 2 ): 233 – 245. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.