Theoretical investigation of the design and performance of a dual energy (kV and MV) radiotherapy imager
dc.contributor.author | Liu, Langechuan | |
dc.contributor.author | Antonuk, Larry E. | |
dc.contributor.author | El‐mohri, Youcef | |
dc.contributor.author | Zhao, Qihua | |
dc.contributor.author | Jiang, Hao | |
dc.date.accessioned | 2017-01-06T20:48:48Z | |
dc.date.available | 2017-01-06T20:48:48Z | |
dc.date.issued | 2015-04 | |
dc.identifier.citation | Liu, Langechuan; Antonuk, Larry E.; El‐mohri, Youcef ; Zhao, Qihua; Jiang, Hao (2015). "Theoretical investigation of the design and performance of a dual energy (kV and MV) radiotherapy imager." Medical Physics 42(4): 2072-2084. | |
dc.identifier.issn | 0094-2405 | |
dc.identifier.issn | 2473-4209 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/134977 | |
dc.publisher | American Association of Physicists in Medicine | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.subject.other | Scintillation detectors | |
dc.subject.other | Computerised tomographs | |
dc.subject.other | Radiation therapy | |
dc.subject.other | Biological material, e.g. blood, urine; Haemocytometers | |
dc.subject.other | Measurement of nuclear or xâ radiation | |
dc.subject.other | Tubes for determining the presence, intensity, density or energy of radiation or particles | |
dc.subject.other | Imager structures | |
dc.subject.other | the detector being a crystal | |
dc.subject.other | the detector being made of plastics | |
dc.subject.other | the detector being a liquid | |
dc.subject.other | with semiconductor detectors | |
dc.subject.other | Plates or blocks in which tracks of nuclear particles are made visible by afterâ treatment, e.g. using photographic emulsion, using mica | |
dc.subject.other | dual energy imager | |
dc.subject.other | megavoltage coneâ beam CT | |
dc.subject.other | kilovoltage coneâ beam CT | |
dc.subject.other | flatâ panel imager | |
dc.subject.other | active matrix flat panel imager | |
dc.subject.other | hybrid modeling | |
dc.subject.other | Monte Carlo simulation | |
dc.subject.other | segmented crystalline scintillators | |
dc.subject.other | Image converters | |
dc.subject.other | Medical Xâ ray imaging | |
dc.subject.other | Medical image noise | |
dc.subject.other | Modulation transfer functions | |
dc.subject.other | Medical image reconstruction | |
dc.subject.other | Illumination | |
dc.subject.other | Medical image contrast | |
dc.subject.other | Cone beam computed tomography | |
dc.subject.other | biological tissues | |
dc.subject.other | computerised tomography | |
dc.subject.other | image sensors | |
dc.subject.other | noise | |
dc.subject.other | optical transfer function | |
dc.subject.other | quality assurance | |
dc.subject.other | radiation therapy | |
dc.subject.other | solid scintillation detectors | |
dc.subject.other | Computed tomography | |
dc.subject.other | Therapeutic applications, including brachytherapy | |
dc.subject.other | Photons | |
dc.title | Theoretical investigation of the design and performance of a dual energy (kV and MV) radiotherapy imager | |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Medicine (General) | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.description.peerreviewed | Peer Reviewed | |
dc.contributor.affiliationum | Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109 | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/134977/1/mp5120.pdf | |
dc.identifier.doi | 10.1118/1.4915120 | |
dc.identifier.source | Medical Physics | |
dc.identifier.citedreference | D. Roberts, V. Hansen, M. Thompson, G. Poludniowski, A. Niven, J. Seco, and P. Evans, â Kilovoltage energy imaging with a radiotherapy linac with a continuously variable energy range,â Med. Phys. 39, 1218 â 1226 ( 2012 ). 10.1118/1.3681011 | |
dc.identifier.citedreference | L. E. Antonuk, â Electronic portal imaging devices: A review and historical perspective of contemporary technologies and research,â Phys. Med. Biol. 47, R31 â R65 ( 2002 ). 10.1088/0031â 9155/47/2/401 | |
dc.identifier.citedreference | N. Mail, D. Moseley, J. Siewerdsen, and D. Jaffray, â The influence of bowtie filtration on coneâ beam CT image quality,â Med. Phys. 36, 22 â 32 ( 2009 ). 10.1118/1.3017470 | |
dc.identifier.citedreference | M. Aubin, O. Morin, J. Chen, A. Gillis, B. Pickett, J. Aubry, C. Akazawa, J. Speight, M. Roach III, and J. Pouliot, â The use of megavoltage coneâ beam CT to complement CT for target definition in pelvic radiotherapy in the presence of hip replacement,â Br. J. Radiol. 79, 918 â 921 ( 2006 ). 10.1259/bjr/19559792 | |
dc.identifier.citedreference | O. Morin, J. Chen, M. Aubin, A. Gillis, J.â F. Aubry, S. Bose, H. Chen, M. Descovich, P. Xia, and J. Pouliot, â Dose calculation using megavoltage coneâ beam CT,â Int. J. Radiat. Oncol., Biol., Phys. 67, 1201 â 1210 ( 2007 ). 10.1016/j.ijrobp.2006.10.048 | |
dc.identifier.citedreference | Y. Elâ Mohri, K.â W. Jee, L. E. Antonuk, M. Maolinbay, and Q. Zhao, â Determination of the detective quantum efficiency of a prototype, megavoltage indirect detection, active matrix flatâ panel imager,â Med. Phys. 28, 2538 â 2550 ( 2001 ) 10.1118/1.1413516; Erratum: Y. Elâ Mohri, K.â W. Jee, L. E. Antonuk, M. Maolinbay, and Q. Zhao, Med. Phys. 33, 251 ( 2006 ). 10.1118/1.2135910 | |
dc.identifier.citedreference | B. A. Groh, J. H. Siewerdsen, D. G. Drake, J. W. Wong, and D. A. Jaffray, â A performance comparison of flatâ panel imagerâ based MV and kV coneâ beam CT,â Med. Phys. 29, 967 â 975 ( 2002 ). 10.1118/1.1477234 | |
dc.identifier.citedreference | E. C. Ford, J. Chang, K. Mueller, K. Sidhu, D. Todor, G. Mageras, E. Yorke, C. C. Ling, and H. Amols, â Coneâ beam CT with megavoltage beams and an amorphous silicon electronic portal imaging device: Potential for verification of radiotherapy of lung cancer,â Med. Phys. 29, 2913 â 2924 ( 2002 ). 10.1118/1.1517614 | |
dc.identifier.citedreference | T. R. Mackie, â History of tomotherapy,â Phys. Med. Biol. 51, R427 â R453 ( 2006 ). 10.1088/0031â 9155/51/13/r24 | |
dc.identifier.citedreference | H. Keller, M. Glass, R. Hinderer, K. Ruchala, R. Jeraj, G. Olivera, and T. R. Mackie, â Monte Carlo study of a highly efficient gas ionization detector for megavoltage imaging and imageâ guided radiotherapy,â Med. Phys. 29, 165 â 175 ( 2002 ). 10.1118/1.1445414 | |
dc.identifier.citedreference | S. Rathee, D. Tu, T. T. Monajemi, D. W. Rickey, and B. G. Fallone, â A benchâ top megavoltage fanâ beam CT using CdWO4â photodiode detectors. I. System description and detector characterization,â Med. Phys. 33, 1078 â 1089 ( 2006 ). 10.1118/1.2181290 | |
dc.identifier.citedreference | S. S. Samant and A. Gopal, â Analysis of the kinestatic charge detection system as a high detective quantum efficiency electronic portal imaging device,â Med. Phys. 33, 3557 â 3567 ( 2006 ). 10.1118/1.2241991 | |
dc.identifier.citedreference | P. F. Kirvan, T. T. Monajemi, B. G. Fallone, and S. Rathee, â Performance characterization of a MVCT scanner using multislice thick, segmented cadmium tungstateâ photodode detectors,â Med. Phys. 37, 249 â 257 ( 2010 ). 10.1118/1.3273032 | |
dc.identifier.citedreference | M. A. Moslehâ Shirazi, P. M. Evans, W. Swindell, J. R. N. Symondsâ Tayler, S. Webb, and M. Partridge, â Rapid portal imaging with a highâ efficiency, large fieldâ ofâ view detector,â Med. Phys. 25, 2333 â 2346 ( 1998 ). 10.1118/1.598443 | |
dc.identifier.citedreference | E. J. Seppi, P. Munro, S. W. Johnsen, E. G. Shapiro, C. Tognina, D. Jones, J. M. Pavkovich, C. Webb, I. Mollov, L. D. Partain, and R. E. Colbeth, â Megavoltage coneâ beam computed tomography using a highâ efficiency image receptor,â Int. J. Radiat. Oncol., Biol., Phys. 55, 793 â 803 ( 2003 ). 10.1016/s0360â 3016(02)04155â x | |
dc.identifier.citedreference | A. Sawant, L. E. Antonuk, Y. Elâ Mohri, Y. Li, Z. Su, Y. Wang, J. Yamamoto, Q. Zhao, H. Du, and J. Daniel, â Segmented phosphors: Memsâ based high quantum efficiency detectors for megavoltage xâ ray imaging,â Med. Phys. 32, 553 â 565 ( 2005 ). 10.1118/1.1854774 | |
dc.identifier.citedreference | E. K. Breitbach, J. S. Maltz, B. Gangadharan, A. Baniâ Hashemi, C. M. Anderson, S. K. Bhatia, J. Stiles, D. S. Edwards, and R. T. Flynn, â Image quality improvement in megavoltage cone beam CT using an imaging beam line and a sintered pixelated array system,â Med. Phys. 38, 5969 â 5979 ( 2011 ). 10.1118/1.3651470 | |
dc.identifier.citedreference | A. Sawant, L. E. Antonuk, Y. Elâ Mohri, Q. Zhao, Y. Wang, Y. Li, H. Du, and L. Perna, â Segmented crystalline scintillators: Empirical and theoretical investigation of a high quantum efficiency EPID based on an initial engineering prototype CsI(Tl) detector,â Med. Phys. 33, 1053 â 1066 ( 2006 ). 10.1118/1.2178452 | |
dc.identifier.citedreference | Y. Wang, L. E. Antonuk, Y. Elâ Mohri, Q. Zhao, A. Sawant, and H. Du, â Monte Carlo investigations of megavoltage coneâ beam CT using thick, segmented scintillating detectors for soft tissue visualization,â Med. Phys. 35, 145 â 158 ( 2008 ). 10.1118/1.2818957 | |
dc.identifier.citedreference | Y. Wang, L. E. Antonuk, Q. Zhao, Y. Elâ Mohri, and L. Perna, â Highâ DQE EPIDs based on thick, segmented BGO and CsI: Tl scintillators: Performance evaluation at extremely low dose,â Med. Phys. 36, 5707 â 5718 ( 2009 ). 10.1118/1.3259721 | |
dc.identifier.citedreference | Y. Wang, L. E. Antonuk, Y. Elâ Mohri, and Q. Zhao, â A Monte Carlo investigation of Swank noise for thick, segmented, crystalline scintillators for radiotherapy imaging,â Med. Phys. 36, 3227 â 3238 ( 2009 ). 10.1118/1.3125821 | |
dc.identifier.citedreference | Y. Elâ Mohri, L. E. Antonuk, Q. Zhao, R. B. Choroszucha, H. Jiang, and L. Liu, â Lowâ dose megavoltage coneâ beam CT imaging using thick, segmented scintillators,â Phys. Med. Biol. 56, 1509 â 1527 ( 2011 ). 10.1088/0031â 9155/56/6/001 | |
dc.identifier.citedreference | L. Liu, L. E. Antonuk, Q. Zhao, Y. Elâ Mohri, and H. Jiang, â Countering beam divergence effects with focused segmented scintillators for high DQE megavoltage active matrix imagers,â Phys. Med. Biol. 57, 5343 â 5358 ( 2012 ). 10.1088/0031â 9155/57/16/5343 | |
dc.identifier.citedreference | Y. Elâ Mohri, L. E. Antonuk, R. B. Choroszucha, Q. Zhao, H. Jiang, and L. Liu, â Optimization of the performance of segmented scintillators for radiotherapy imaging through novel binning techniques,â Phys. Med. Biol. 59, 797 â 818 ( 2014 ). 10.1088/0031â 9155/59/4/797 | |
dc.identifier.citedreference | L. Liu, L. E. Antonuk, Y. Elâ Mohri, Q. Zhao, and H. Jiang, â Optimization of the design of thick, segmented scintillators for megavoltage coneâ beam CT using a novel, hybrid modeling technique,â Med. Phys. 41, 061916 (14pp.) ( 2014 ). 10.1118/1.4875724 | |
dc.identifier.citedreference | M. Weissbluth, C. Karzmark, R. Steele, and A. Selby, â The Stanford medical linear accelerator: II. Installation and physical measurements 1,â Radiology 72, 242 â 265 ( 1959 ). 10.1148/72.2.242 | |
dc.identifier.citedreference | H. Johns and J. Cunningham, â A precision cobalt 60 unit for fixed field and rotation therapy,â Am. J. Roentgenol., Radium Ther. Nucl. Med. 81, 4 â 12 ( 1959 ). | |
dc.identifier.citedreference | Y. Cho and P. Munro, â Kilovision: Thermal modeling of a kilovoltage xâ ray source integrated into a medical linear accelerator,â Med. Phys. 29, 2101 â 2108 ( 2002 ). 10.1118/1.1501142 | |
dc.identifier.citedreference | D. M. Galbraith, â Lowâ energy imaging with highâ energy bremsstrahlung beams,â Med. Phys. 16, 734 â 746 ( 1989 ). 10.1118/1.596332 | |
dc.identifier.citedreference | B. A. Faddegon, V. Wu, J. Pouliot, B. Gangadharan, and A. Baniâ Hashemi, â Low dose megavoltage cone beam computed tomography with an unflattened 4 MV beam from a carbon target,â Med. Phys. 35, 5777 â 5786 ( 2008 ). 10.1118/1.3013571 | |
dc.identifier.citedreference | J. L. Robar, T. Connell, W. Huang, and R. G. Kelly, â Megavoltage planar and coneâ beam imaging with lowâ Z targets: Dependence of image quality improvement on beam energy and patient separation,â Med. Phys. 36, 3955 â 3963 ( 2009 ). 10.1118/1.3183499 | |
dc.identifier.citedreference | D. Parsons, J. L. Robar, and D. Sawkey, â A Monte Carlo investigation of lowâ Z target image quality generated in a linear accelerator using varian’s virtualinac,â Med. Phys. 41, 021719 (6pp.) ( 2014 ). 10.1118/1.4861818 | |
dc.identifier.citedreference | J. Rottmann, M. Aristophanous, A. Chen, L. Court, and R. Berbeco, â A multiâ region algorithm for markerless beam’sâ eye view lung tumor tracking,â Phys. Med. Biol. 55, 5585 â 5598 ( 2010 ). 10.1088/0031â 9155/55/18/021 | |
dc.identifier.citedreference | F.â F. Yin, H. Guan, and W. Lu, â A technique for onâ board CT reconstruction using both kilovoltage and megavoltage beam projections for 3D treatment verification,â Med. Phys. 32, 2819 â 2826 ( 2005 ). 10.1118/1.1997307 | |
dc.identifier.citedreference | T. Falco and B. G. Fallone, â Characteristics of metalâ plate/film detectors at therapy energies. I. Modulation transfer function,â Med. Phys. 25, 2455 â 2462 ( 1998 ). 10.1118/1.598436 | |
dc.identifier.citedreference | C. Kausch, B. Schreiber, F. Kreuder, R. Schmidt, and O. Dössel, â Monte Carlo simulations of the imaging performance of metal plate/phosphor screens used in radiotherapy,â Med. Phys. 26, 2113 â 2124 ( 1999 ). 10.1118/1.598727 | |
dc.identifier.citedreference | J. Yorkston, L. E. Antonuk, Y. Elâ Mohri, K.â W. Jee, W. Huang, M. Maolinbay, X. Rong, J. H. Siewerdsen, and D. P. Trauernicht, â Improved spatial resolution in flatâ panel imaging systems,â Proc. SPIE 3336, 556 â 563 ( 1998 ). 10.1117/12.317058 | |
dc.identifier.citedreference | Y. Elâ Mohri, L. E. Antonuk, Q. Zhao, Y. Wang, Y. Li, H. Du, and A. Sawant, â Performance of a high fill factor, indirect detection prototype flatâ panel imager for mammography,â Med. Phys. 34, 315 â 327 ( 2007 ). 10.1118/1.2403967 | |
dc.identifier.citedreference | F. H. Attix, Introduction to Radiological Physics and Radiation Dosimetry ( Wileyâ VCH Verlag GmbH & Co., Weinheim, 2004 ). | |
dc.identifier.citedreference | K. Sato, F. Nariyuki, H. Nomura, A. Takasu, S. Fukui, M. Nakatsu, Y. Okada, T. Nabeta, and Y. Hosoi, â Effect of xâ ray incident direction and scintillator layer design on image quality of indirectâ conversion flatâ panel detector with GOS phosphor,â Proc. SPIE 7961, 79614I ( 2011 ). 10.1117/12.877752 | |
dc.identifier.citedreference | S. Rivetti, N. Lanconelli, M. Bertolini, A. Nitrosi, and A. Burani, â Characterization of a clinical unit for digital radiography based on irradiation side sampling technology,â Med. Phys. 40, 101902 (11pp.) ( 2013 ). 10.1118/1.4820364 | |
dc.identifier.citedreference | I. Kawrakow and D. W. O. Rogers, â The EGSnrc code system: Monte carlo simulation of electron and photon transport,â Technical Report No. PIRSâ 701 ( National Research Council of Canada, Ottawa, Canada, 2000 ). | |
dc.identifier.citedreference | I. Kawrakow, â egspp: The EGSnrc c++ class library,â Technical Report No. PIRSâ 899 ( National Research Council of Canada, Ottawa, Canada, 2005 ). | |
dc.identifier.citedreference | J. M. Boone and J. A. Seibert, â An accurate method for computerâ generating tungsten anode xâ ray spectra from 30 to 140 kV,â Med. Phys. 24, 1661 â 1670 ( 1997 ). 10.1118/1.597953 | |
dc.identifier.citedreference | D. Sheikhâ Bagheri, Ph.D. thesis, Carleton University, Ottawa, 1999. | |
dc.identifier.citedreference | S. Agostinelli et al., â geant4 â A simulation toolkit,â Nucl. Instrum. Methods Phys. Res., Sect. A 506, 250 â 303 ( 2003 ). 10.1016/s0168â 9002(03)01368â 8 | |
dc.identifier.citedreference | M. Maolinbay, Y. Elâ Mohri, L. Antonuk, K.â W. Jee, S. Nassif, X. Rong, and Q. Zhao, â Additive noise properties of active matrix flatâ panel imagers,â Med. Phys. 27, 1841 â 1854 ( 2000 ). 10.1118/1.1286721 | |
dc.identifier.citedreference | P. A. Tipler and G. Mosca, Physics for Scientists and Engineers, 6 ed. ( Freeman, W. H. & Company, New York, NY, 2007 ). | |
dc.identifier.citedreference | L. E. Antonuk, Q. Zhao, Y. Elâ Mohri, H. Du, Y. Wang, R. A. Street, J. Ho, R. Weisfield, and W. Yao, â An investigation of signal performance enhancements achieved through innovative pixel design across several generations of indirect detection, active matrix, flatâ panel arrays,â Med. Phys. 36, 3322 â 3339 ( 2009 ). 10.1118/1.3049602 | |
dc.identifier.citedreference | M. Maolinbay, T. Zimmerman, R. Yarema, L. Antonuk, Y. Elâ Mohri, and M. Yeakey, â Design and performance of a low noise, 128â channel ASIC preamplifier for readout of active matrix flatâ panel imaging arrays,â Nucl. Instrum. Methods Phys. Res., Sect. A 485, 661 â 675 ( 2002 ). 10.1016/s0168â 9002(01)02129â 5 | |
dc.identifier.citedreference | M. F. Fast, T. Koenig, U. Oelfke, and S. Nill, â Performance characteristics of a novel megavoltage coneâ beamâ computed tomography device,â Phys. Med. Biol. 57, N15 â N24 ( 2012 ). 10.1088/0031â 9155/57/3/n15 | |
dc.identifier.citedreference | H. Fujita, D. Tsai, T. Itoh, K. Doi, J. Morishita, K. Ueda, and A. Ohtsuka, â A simple method for determining the modulation transfer function in digital radiography,â IEEE Trans. Med. Imaging 11, 34 â 39 ( 1992 ). 10.1109/42.126908 | |
dc.identifier.citedreference | R. K. Swank, â Absorption and noise in xâ ray phosphors,â J. Appl. Phys. 44, 4199 â 4203 ( 1973 ). 10.1063/1.1662918 | |
dc.identifier.citedreference | W. Zhao, G. Ristic, and J. A. Rowlands, â Xâ ray imaging performance of structured cesium iodide scintillators,â Med. Phys. 31, 2594 â 2605 ( 2004 ). 10.1118/1.1782676 | |
dc.identifier.citedreference | E. Samei, â Image quality in two phosphorâ based flat panel digital radiographic detectors,â Med. Phys. 30, 1747 â 1757 ( 2003 ). 10.1118/1.1578772 | |
dc.identifier.citedreference | Y. Wang, Y. Elâ Mohri, L. E. Antonuk, and Q. Zhao, â Monte Carlo investigations of the effect of beam divergence on thick, segmented crystalline scintillators for radiotherapy imaging,â Phys. Med. Biol. 55, 3659 â 3673 ( 2010 ). 10.1088/0031â 9155/55/13/006 | |
dc.identifier.citedreference | R. A. Street, W. S. Wong, and R. Lujan, â Curved electronic pixel arrays using a cut and bend approach,â J. Appl. Phys. 105, 104504 ( 2009 ). 10.1063/1.3129315 | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.