Potential for doseâ escalation and reduction of risk in pancreatic cancer using IMRT optimization with lexicographic ordering and gEUDâ based cost functions
dc.contributor.author | Spalding, Aaron C. | |
dc.contributor.author | Jee, Kyung‐wook | |
dc.contributor.author | Vineberg, Karen | |
dc.contributor.author | Jablonowski, Marla | |
dc.contributor.author | Fraass, Benedick A. | |
dc.contributor.author | Pan, Charlie C. | |
dc.contributor.author | Lawrence, Theodore S. | |
dc.contributor.author | Ten Haken, Randall K. | |
dc.contributor.author | Ben‐josef, Edgar | |
dc.date.accessioned | 2017-01-06T20:50:19Z | |
dc.date.available | 2017-01-06T20:50:19Z | |
dc.date.issued | 2007-02 | |
dc.identifier.citation | Spalding, Aaron C.; Jee, Kyung‐wook ; Vineberg, Karen; Jablonowski, Marla; Fraass, Benedick A.; Pan, Charlie C.; Lawrence, Theodore S.; Ten Haken, Randall K.; Ben‐josef, Edgar (2007). "Potential for doseâ escalation and reduction of risk in pancreatic cancer using IMRT optimization with lexicographic ordering and gEUDâ based cost functions." Medical Physics 34(2): 521-529. | |
dc.identifier.issn | 0094-2405 | |
dc.identifier.issn | 2473-4209 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/135067 | |
dc.publisher | American Association of Physicists in Medicine | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.subject.other | Pancreatic cancer | |
dc.subject.other | equivalent uniform dose | |
dc.subject.other | intensity modulated radiation therapy | |
dc.subject.other | lexicographic ordering | |
dc.subject.other | Dosimetry | |
dc.subject.other | Cancer | |
dc.subject.other | Intensity modulated radiation therapy | |
dc.subject.other | Tissues | |
dc.subject.other | Anatomy | |
dc.subject.other | Radiation therapy | |
dc.subject.other | Medical treatment planning | |
dc.subject.other | Optimization | |
dc.subject.other | Chemotherapy | |
dc.subject.other | Vascular system | |
dc.subject.other | radiation therapy | |
dc.subject.other | Wedges and compensators | |
dc.subject.other | Treatment strategy | |
dc.subject.other | Radiation therapy equipment | |
dc.subject.other | Diseases | |
dc.subject.other | Conformal radiation treatment | |
dc.subject.other | dosimetry | |
dc.subject.other | biological organs | |
dc.subject.other | cancer | |
dc.subject.other | tumours | |
dc.subject.other | optimisation | |
dc.title | Potential for doseâ escalation and reduction of risk in pancreatic cancer using IMRT optimization with lexicographic ordering and gEUDâ based cost functions | |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Medicine (General) | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.description.peerreviewed | Peer Reviewed | |
dc.contributor.affiliationum | Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109â 0010 | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/135067/1/mp6403.pdf | |
dc.identifier.doi | 10.1118/1.2426403 | |
dc.identifier.source | Medical Physics | |
dc.identifier.citedreference | P. Gill, W. Murray, and M. Saunders, â SNOPT: An SQP algorithm for largeâ scale constrained optimization,â SIAM J. Optim. SJOPE8 --> 1052‐6234 --> 10.1137/S1052623499350013 --> 12, 979 â 1006 ( 2002 ). | |
dc.identifier.citedreference | N. J. Lygidakis, G. Singh, E. Bardaxoglou, G. Dedemadi, G. Sgourakis, J. Nestoridis, A. Malliotakis, M. Pedonomou, E. K. Solomou, M. Safioleas, M. Alamani, L. Grigorakos, and E. M. Merikas, â Monoâ bloc total splenoâ pancreaticoduodenectomy for pancreatic head carcinoma with portalâ mesenteric venous invasion. A prospective randomized study,â Hepatoâ Gastroenterology HEGAD4 --> 0172‐6390 --> 51, 427 â 433 ( 2004 ). | |
dc.identifier.citedreference | M. Schwarz, M. Alber, J. V. Lebesque, B. J. Mijnheer, and E. M. Damen, â Dose heterogeneity in the target volume and intensityâ modulated radiotherapy to escalate the dose in the treatment of nonâ smallâ cell lung cancer,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2005.02.011 --> 62, 561 â 570 ( 2005 ). | |
dc.identifier.citedreference | B. Choi and J. O. Deasy, â The generalized equivalent uniform dose function as a basis for intensityâ modulated treatment planning,â Phys. Med. Biol. PHMBA7 --> 0031‐9155 --> 10.1088/0031‐9155/47/20/302 --> 47, 3579 â 3589 ( 2002 ). | |
dc.identifier.citedreference | A. Niemierko, â A generalized concept of equivalent uniform dose (EUD) [Abstract],â Med. Phys. MPHYA6 --> 0094‐2405 --> 26, 1100 ( 1999 ). | |
dc.identifier.citedreference | C. Thieke, T. Bortfeld, A. Niemierko, and S. Nill, â From physical dose constraints to equivalent uniform dose constraints in inverse radiotherapy planning,â Med. Phys. MPHYA6 --> 0094‐2405 --> 10.1118/1.1598852 --> 30, 2332 â 2339 ( 2003 ). | |
dc.identifier.citedreference | E. Thomas, O. Chapet, M. L. Kessler, T. S. Lawrence, and R. K. Ten Haken, â Benefit of using biologic parameters (EUD and NTCP) in IMRT optimization for treatment of intrahepatic tumors,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2005.02.033 --> 62, 571 â 578 ( 2005 ). | |
dc.identifier.citedreference | Q. Wu, R. Mohan, A. Niemierko, and R. Schmidtâ Ullrich, â Optimization of intensityâ modulated radiotherapy plans based on the equivalent uniform dose,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/S0360‐3016(01)02585‐8 --> 52, 224 â 235 ( 2002 ). | |
dc.identifier.citedreference | O. Chapet, E. Thomas, M. L. Kessler, B. A. Fraass, and R. K. Ten Haken, â Esophagus sparing with IMRT in lung tumor irradiation: An EUDâ based optimization technique,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2005.01.028 --> 63, 179 â 187 ( 2005 ). | |
dc.identifier.citedreference | C. Cotrutz, M. Lahanas, C. Kappas, and D. Baltas, â A multiobjective gradientâ based dose optimization algorithm for external beam conformal radiotherapy,â Phys. Med. Biol. PHMBA7 --> 0031‐9155 --> 10.1088/0031‐9155/46/8/309 --> 46, 2161 â 2175 ( 2001 ). | |
dc.identifier.citedreference | E. Schreibmann, M. Lahanas, L. Xing, and D. Baltas, â Multiobjective evolutionary optimization of the number of beams, their orientations and weights for intensityâ modulated radiation therapy,â Phys. Med. Biol. PHMBA7 --> 0031‐9155 --> 10.1088/0031‐9155/49/5/007 --> 49, 747 â 770 ( 2004 ). | |
dc.identifier.citedreference | K. Miettinen, Nonlinear Multiobjective Optimization ( Kluwer, Boston, 1999 ). | |
dc.identifier.citedreference | C. J. McGinn, M. M. Zalupski, I. Shureiqi, J. M. Robertson, F. E. Eckhauser, D. C. Smith, D. Brown, G. Hejna, M. Strawderman, D. Normolle, and T. S. Lawrence, â Phase I trial of radiation dose escalation with concurrent weekly fullâ dose gemcitabine in patients with advanced pancreatic cancer,â J. Clin. Oncol. JCONDN --> 0732‐183X --> 19, 4202 â 4208 ( 2001 ). | |
dc.identifier.citedreference | E. Benâ Josef, A. F. Shields, U. Vaishampayan, V. Vaitkevicius, B. F. Elâ Rayes, P. McDermott, J. Burmeister, T. Bossenberger, and P. A. Philip, â Intensityâ modulated radiotherapy (IMRT) and concurrent capecitabine for pancreatic cancer,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2003.11.019 --> 59, 454 â 459 ( 2004 ). | |
dc.identifier.citedreference | K.â W. Jee, D. L. McShan, and B. A. Fraass, â Intuitive Multicriteria IMRT Optimization Using a Lexicographic Approach [Abstract],â Med. Phys. MPHYA6 --> 0094‐2405 --> 10.1118/1.1796952 --> 31, 1715 ( 2004 ). | |
dc.identifier.citedreference | K. Jee, B. Fraass and D. McShan, â Implementation of automatic differentiation tools for multicriteria IMRT optimization,â in Automatic Differentiation: Applications, Theory, and Tools, Lecture Notes in Computational Science and Engineering 50 ( Springer, 2005 ), pp. 225 â 234. | |
dc.identifier.citedreference | K.â W. Jee, D. L. McShan, K. A. Vineberg, and B. A. Fraass, â Performance Evaluations of a Preemptive Approach in IMRT Planning [Abstract],â Med. Phys. MPHYA6 --> 0094‐2405 --> 33, 2128 ( 2006 ). | |
dc.identifier.citedreference | M. Kessler, D. McShan, and K. Vineberg, â Costlets: A generalized approach to cost functions for automated optimization,â Optim. Eng. 1389‐4420 --> 6, 421 â 448 ( 2005 ). | |
dc.identifier.citedreference | J. T. Lyman, â Complication probability as assessed from doseâ volume histograms,â Radiat. Res. Suppl. 0485‐8611 --> 8, S13 â 19 ( 1985 ). | |
dc.identifier.citedreference | J. Nocedal and S. Wright, Numerical Optimization ( Springer, New York, 1999 ). | |
dc.identifier.citedreference | T. Bortfeld, J. Stein, and K. Preiser, â Clinically relevant intensity modulation optimization using physical criteria,â Proceedings of the XII International Conference on the Use of Computers in Radiation Therapy, edited by G. Starkschall and D. D. Leavitt ( Advanced Medical Publishing, Madison, WI, 1997 ), pp. 1 â 4. | |
dc.identifier.citedreference | Q. Wu and R. Mohan, â Algorithms and functionality of an intensity modulated radiotherapy optimization system,â Med. Phys. MPHYA6 --> 0094‐2405 --> 10.1118/1.598932 --> 27, 701 â 711 ( 2000 ). | |
dc.identifier.citedreference | J. Lian and L. Xing, â Incorporating model parameter uncertainty into inverse treatment planning,â Med. Phys. MPHYA6 --> 0094‐2405 --> 10.1118/1.1785451 --> 31, 2711 â 2720 ( 2004 ). | |
dc.identifier.citedreference | X. A. Li, J. Z. Wang, P. A. Jursinic, C. A. Lawton, and D. Wang, â Dosimetric advantages of IMRT simultaneous integrated boost for highâ risk prostate cancer,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2004.11.034 --> 61, 1251 â 1257 ( 2005 ). | |
dc.identifier.citedreference | R. K. Ten Haken, T. S. Lawrence, D. L. McShan, R. J. Tesser, B. A. Fraass, and A. S. Lichter, â Technical considerations in the use of 3â D beam arrangements in the abdomen,â Radiother. Oncol. RAONDT --> 0167‐8140 --> 10.1016/0167‐8140(91)90065‐O --> 22, 19 â 28 ( 1991 ). | |
dc.identifier.citedreference | J. M. Robertson, L. Marsh, R. K. Ten Haken, and T. S. Lawrence, â The clinical application of a nonâ axial treatment plan for pancreatic and biliary malignancies,â Radiother. Oncol. RAONDT --> 0167‐8140 --> 10.1016/0167‐8140(92)90381‐4 --> 24, 198 â 200 ( 1992 ). | |
dc.identifier.citedreference | M. Schwarz, J. V. Lebesque, B. J. Mijnheer, and E. M. Damen, â Sensitivity of treatment plan optimisation for prostate cancer using the equivalent uniform dose (EUD) with respect to the rectal wall volume parameter,â Radiother. Oncol. RAONDT --> 0167‐8140 --> 10.1016/j.radonc.2004.08.016 --> 73, 209 â 218 ( 2004 ). | |
dc.identifier.citedreference | T. Rancati, C. Fiorino, G. Gagliardi, G. M. Cattaneo, G. Sanguineti, V. C. Borca, C. Cozzarini, G. Fellin, F. Foppiano, G. Girelli, L. Menegotti, A. Piazzolla, V. Vavassori, and R. Valdagni, â Fitting late rectal bleeding data using different NTCP models: Results from an Italian multiâ centric study (AIROPROS0101),â Radiother. Oncol. RAONDT --> 0167‐8140 --> 10.1016/j.radonc.2004.08.013 --> 73, 21 â 32 ( 2004 ). | |
dc.identifier.citedreference | M. Ghilezan, D. Yan, J. Liang, D. Jaffray, J. Wong, and A. Martinez, â Online imageâ guided intensityâ modulated radiotherapy for prostate cancer: How much improvement can we expect? A theoretical assessment of clinical benefits and potential dose escalation by improving precision and accuracy of radiation delivery,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2004.07.709 --> 60, 1602 â 1610 ( 2004 ). | |
dc.identifier.citedreference | W. A. Tome and J. F. Fowler, â Selective boosting of tumor subvolumes,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/S0360‐3016(00)00666‐0 --> 48, 593 â 599 ( 2000 ). | |
dc.identifier.citedreference | J. O. Deasy, â Partial tumor boosts: Even more attractive than theory predicts?,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/S0360‐3016(01)01611‐X --> 51, 279 â 280 ( 2001 ). | |
dc.identifier.citedreference | M. T. Milano, S. J. Chmura, M. C. Garofalo, C. Rash, J. C. Roeske, P. P. Connell, O. H. Kwon, A. B. Jani, and R. Heimann, â Intensityâ modulated radiotherapy in treatment of pancreatic and bile duct malignancies: Toxicity and clinical outcome,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2003.11.003 --> 59, 445 â 453 ( 2004 ). | |
dc.identifier.citedreference | M. Tsujie, S. Nakamori, E. Tanaka, H. Nagano, K. Umeshita, K. Dono, M. Sakon, T. Inoue, T. Inoue, and M. Monden, â Phase I/II trial of hyperfractionated accelerated chemoradiotherapy for unresectable advanced pancreatic cancer,â Jpn. J. Clin. Oncol. 0368‐2811 --> 36, 504 â 510 ( 2006 ). | |
dc.identifier.citedreference | F. B. Zimmermann, C. Schuhmacher, C. Lersch, B. Bernhardt, P. Pickel, J. R. Siewert, M. Molls, and B. Jeremic, â Sequential and/or concurrent hypofractionated radiotherapy and concurrent chemotherapy in neoadjuvant treatment of advanced adenocarcinoma of the pancreas. Outcome and patterns of failure,â Hepatoâ Gastroenterology HEGAD4 --> 0172‐6390 --> 51, 1842 â 1846 ( 2004 ). | |
dc.identifier.citedreference | M. Hoyer, H. Roed, L. Sengelov, A. Traberg, L. Ohlhuis, J. Pedersen, H. Nellemann, A. Kiil Berthelsen, F. Eberholst, S. A. Engelholm, and H. von der Maase, â Phaseâ II study on stereotactic radiotherapy of locally advanced pancreatic carcinoma,â Radiother. Oncol. RAONDT --> 0167‐8140 --> 10.1016/j.radonc.2004.12.022 --> 76, 48 â 53 ( 2005 ). | |
dc.identifier.citedreference | T. Rich, J. Harris, R. Abrams, B. Erickson, M. Doherty, J. Paradelo, W. Small, Jr., H. Safran, and H. J. Wanebo, â Phase II study of external irradiation and weekly paclitaxel for nonmetastatic unresectable pancreatic cancer: RTOGâ 98â 12,â Am. J. Clin. Oncol. AJCODI --> 0277‐3732 --> 10.1097/01.coc.0000046300.88847.BF --> 27, 51 â 56 ( 2004 ). | |
dc.identifier.citedreference | E. Horst, O. Micke, C. Moustakis, A. Schuck, U. Schafer, and N. A. Willich, â Conformal therapy for pancreatic cancer: Variation of organ position due to gastrointestinal distentionâ implications for treatment planning,â Radiology RADLAX --> 0033‐8419 --> 222, 681 â 686 ( 2002 ). | |
dc.identifier.citedreference | D. P. Gierga, G. T. Chen, J. H. Kung, M. Betke, J. Lombardi, and C. G. Willett, â Quantification of respirationâ induced abdominal tumor motion and its impact on IMRT dose distributions,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2003.09.077 --> 58, 1584 â 1595 ( 2004 ). | |
dc.identifier.citedreference | Y. C. Ahn, S. Shimizu, H. Shirato, T. Hashimoto, Y. Osaka, X. Q. Zhang, T. Abe, M. Hosokawa, and K. Miyasaka, â Application of realâ time tumorâ tracking and gated radiotherapy system for unresectable pancreatic cancer,â Yonsei Med. J. YOMJA9 --> 0513‐5796 --> 45, 584 â 590 ( 2004 ). | |
dc.identifier.citedreference | L. A. Dawson, K. K. Brock, S. Kazanjian, D. Fitch, C. J. McGinn, T. S. Lawrence, R. K. Ten Haken, and J. Balter, â The reproducibility of organ position using active breathing control (ABC) during liver radiotherapy,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/S0360‐3016(01)02653‐0 --> 51, 1410 â 1421 ( 2001 ). | |
dc.identifier.citedreference | M. Fuss, B. J. Salter, S. X. Cavanaugh, C. Fuss, A. Sadeghi, C. D. Fuller, A. Ameduri, J. M. Hevezi, T. S. Herman, and C. R. Thomas, Jr., â Daily ultrasoundâ based imageâ guided targeting for radiotherapy of upper abdominal malignancies,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2003.12.030 --> 59, 1245 â 1256 ( 2004 ). | |
dc.identifier.citedreference | T. Hashimoto, H. Shirato, M. Kato, K. Yamazaki, N. Kurauchi, T. Morikawa, S. Shimizu, Y. C. Ahn, Y. Akine, and K. Miyasaka, â Realâ time monitoring of a digestive tract marker to reduce adverse effects of moving organs at risk (OAR) in radiotherapy for thoracic and abdominal tumors,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2005.01.006 --> 61, 1559 â 1564 ( 2005 ). | |
dc.identifier.citedreference | R. J. Bold, C. Charnsangavej, K. R. Cleary, M. Jennings, A. Madray, S. D. Leach, J. L. Abbruzzese, P. W. Pisters, J. E. Lee, and D. B. Evans, â Major vascular resection as part of pancreaticoduodenectomy for cancer: Radiologic, intraoperative, and pathologic analysis,â J. Gastrointest Surg. 1091‐255X --> 3, 233 â 243 ( 1999 ). | |
dc.identifier.citedreference | J. B. Ammori, L. M. Colletti, M. M. Zalupski, F. E. Eckhauser, J. K. Greenson, J. Dimick, T. S. Lawrence, and C. J. McGinn, â Surgical resection following radiation therapy with concurrent gemcitabine in patients with previously unresectable adenocarcinoma of the pancreas,â J. Gastrointest Surg. 1091‐255X --> 7, 766 â 772 ( 2003 ). | |
dc.identifier.citedreference | A. Sa Cunha, A. Rault, C. Laurent, X. Adhoute, V. Vendrely, G. Bellannee, R. Brunet, D. Collet, and B. Masson, â Surgical resection after radiochemotherapy in patients with unresectable adenocarcinoma of the pancreas,â J. Am. Coll. Surg. 1072‐7515 --> 201, 359 â 365 ( 2005 ). | |
dc.identifier.citedreference | M. Machtay, D. I. Rosenthal, A. A. Chalian, R. Lustig, D. Hershock, L. Miller, G. S. Weinstein, and R. S. Weber, â Pilot study of postoperative reirradiation, chemotherapy, and amifostine after surgical salvage for recurrent headâ andâ neck cancer,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 10.1016/j.ijrobp.2003.10.056 --> 59, 72 â 77 ( 2004 ). | |
dc.identifier.citedreference | A. Jemal, T. Murray, E. Ward, A. Samuels, R. C. Tiwari, A. Ghafoor, E. J. Feuer, and M. J. Thun, â Cancer statistics, 2005,â Caâ Cancer J. Clin. CAMCAM --> 0007‐9235 --> 55, 10 â 30 ( 2005 ). | |
dc.identifier.citedreference | â Treatment of locally unresectable carcinoma of the pancreas: Comparison of combinedâ modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone. Gastrointestinal Tumor Study Group,â J. Natl. Cancer Inst. JNCIEQ --> 0027‐8874 --> 10.1093/jnci/80.10.751 --> 80, 751 â 755 ( 1988 ). | |
dc.identifier.citedreference | D. Li, K. Xie, R. Wolff, and J. L. Abbruzzese, â Pancreatic cancer,â Lancet LANCAO --> 0140‐6736 --> 10.1016/S0140‐6736(04)15841‐8 --> 363, 1049 â 1057 ( 2004 ). | |
dc.identifier.citedreference | R. J. Geer and M. F. Brennan, â Prognostic indicators for survival after resection of pancreatic adenocarcinoma,â Am. J. Surg. AJSUAB --> 0002‐9610 --> 10.1016/S0002‐9610(05)80406‐4 --> 165, 68 â 72; discussion 72â 63 ( 1993 ). | |
dc.identifier.citedreference | G. E. Roldan, L. L. Gunderson, D. M. Nagorney, J. K. Martin, D. M. Ilstrup, M. A. Holbrook, L. K. Kvols, and D. C. McIlrath, â External beam versus intraoperative and external beam irradiation for locally advanced pancreatic cancer,â Cancer 0008‐543X --> 61, 1110 â 1116 ( 1988 ). | |
dc.identifier.citedreference | C. G. Moertel, S. Frytak, R. G. Hahn, M. J. O’Connell, R. J. Reitemeier, J. Rubin, A. J. Schutt, L. H. Weiland, D. S. Childs, M. A. Holbrook, P. T. Lavin, E. Livstone, H. Spiro, A. Knowlton, M. Kalser, J. Barkin, H. Lessner, R. Mannâ Kaplan, K. Ramming, H. O. Douglas, Jr., P. Thomas, H. Nave, J. Bateman, J. Lokich, J. Brooks, J. Chaffey, J. M. Corson, N. Zamcheck, and J. W. Novak, â Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose ( 6000 rads ) radiation alone, moderate dose radiation ( 4000 rads + 5 â fluorouracil ), and high dose radiation + 5â fluorouracil: The Gastrointestinal Tumor Study Group,â Cancer 0008‐543X --> 48, 1705 â 1710 ( 1981 ). | |
dc.identifier.citedreference | D. J. Klaassen, J. M. MacIntyre, G. E. Catton, P. F. Engstrom, and C. G. Moertel, â Treatment of locally unresectable cancer of the stomach and pancreas: A randomized comparison of 5â fluorouracil alone with radiation plus concurrent and maintenance 5â fluorouracilâ an Eastern Cooperative Oncology Group study,â J. Clin. Oncol. JCONDN --> 0732‐183X --> 3, 373 â 378 ( 1985 ). | |
dc.identifier.citedreference | R. R. Dobelbower, Jr., H. W. Merrick, 3rd, R. K. Ahuja, and R. T. Skeel, â 125I interstitial implant, precision highâ dose external beam therapy, and 5â FU for unresectable adenocarcinoma of pancreas and extrahepatic biliary tree,â Cancer 0008‐543X --> 58, 2185 â 2195 ( 1986 ). | |
dc.identifier.citedreference | M. Mohiuddin, F. Rosato, D. Barbot, A. Schuricht, W. Biermann, and R. Cantor, â Longâ term results of combined modality treatment with Iâ 125 implantation for carcinoma of the pancreas,â Int. J. Radiat. Oncol., Biol., Phys. IOBPD3 --> 0360‐3016 --> 23, 305 â 311 ( 1992 ). | |
dc.identifier.citedreference | M. Mohiuddin, W. F. Regine, J. Stevens, F. Rosato, D. Barbot, W. Biermann, and R. Cantor, â Combined intraoperative radiation and perioperative chemotherapy for unresectable cancers of the pancreas,â J. Clin. Oncol. JCONDN --> 0732‐183X --> 13, 2764 â 2768 ( 1995 ). | |
dc.identifier.citedreference | H. M. Ceha, G. van Tienhoven, D. J. Gouma, C. H. Veenhof, C. J. Schneider, E. A. Rauws, S. S. Phoa, and D. Gonzalez Gonzalez, â Feasibility and efficacy of high dose conformal radiotherapy for patients with locally advanced pancreatic carcinoma,â Cancer 0008‐543X --> 89, 2222 â 2229 ( 2000 ). | |
dc.identifier.citedreference | S. Jain, M. Sacchi, P. Vrachnos, and N. J. Lygidakis, â Carcinoma of the pancreas with portal vein involvementâ our experience with a modified technique of resection,â Hepatoâ Gastroenterology HEGAD4 --> 0172‐6390 --> 52, 1596 â 1600 ( 2005 ). | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.