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Vaginal delivery and serum markers of ischemia/reperfusion injury
dc.contributor.authorConner, E.
dc.contributor.authorMargulies, R.
dc.contributor.authorLiu, Mengling
dc.contributor.authorSmilen, S.W.
dc.contributor.authorPorges, R.F.
dc.contributor.authorKwon, C.
dc.date.accessioned2017-01-10T19:08:21Z
dc.date.available2017-01-10T19:08:21Z
dc.date.issued2006-08
dc.identifier.citationConner, E.; Margulies, R.; Liu, Mengling; Smilen, S.W.; Porges, R.F.; Kwon, C. (2006). "Vaginal delivery and serum markers of ischemia/reperfusion injury." International Journal of Gynecology & Obstetrics 94(2): 96-102.
dc.identifier.issn0020-7292
dc.identifier.issn1879-3479
dc.identifier.urihttps://hdl.handle.net/2027.42/135489
dc.description.abstractObjective: Vaginal deliveries have been associated with pelvic organ prolapse and incontinence. The objective was to show whether markers of ischemia/reperfusion injury are dependent upon the mode of delivery and length of labor. Method: Complete venipuncture sets were obtained on 62 subjects. All samples collected were analyzed for serum creatine phosphokinase (CPK) and lactate dehydrogenase (LDH). Lipid peroxidation was analyzed, using thiobarbituric acid reactive substances (TBARS), on a subset of 37 patients. Results: There was a significant increase in CPK from admission to 1 h postpartum and postpartum day 1 in vaginal delivery versus cesarean delivery. Longer second stages were associated with significant increases in CPK. There were no significant changes in either LDH or TBARS from admission to any other time point regardless of mode of delivery. Conclusion: Vaginal delivery and longer second stages were associated with a much greater increase in one of these injury markers.
dc.publisherWiley Periodicals, Inc.
dc.subject.otherLipid peroxidation
dc.subject.otherCreatine phosphokinase
dc.subject.otherPelvic floor
dc.subject.otherReperfusion injury
dc.titleVaginal delivery and serum markers of ischemia/reperfusion injury
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelObstetrics and Gynecology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.contributor.affiliationumDivision of Gynecology, University of Michigan Health System, Ann Arbor, USA
dc.contributor.affiliationotherDepartment of Obstetrics and Gynecology, Jersey Shore University Medical Center, Neptune, New Jersey, USA
dc.contributor.affiliationotherDivision of Biostatistics, New York University Medical Center New York, USA
dc.contributor.affiliationotherDepartment of Obstetrics and Gynecology, Division of Urogynecology, New York University Medical Center New York, NY, USA
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/135489/1/ijgo96.pdf
dc.identifier.doi10.1016/j.ijgo.2006.04.039
dc.identifier.sourceInternational Journal of Gynecology & Obstetrics
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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