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Deferoxamine: potential novel topical therapeutic for chronic wounds
dc.contributor.authorTchanque‐fossuo, C.n.
dc.contributor.authorDahle, S.E.
dc.contributor.authorBuchman, S.R.
dc.contributor.authorRivkah Isseroff, R.
dc.date.accessioned2017-05-10T17:48:48Z
dc.date.available2018-05-15T21:02:51Zen
dc.date.issued2017-04
dc.identifier.citationTchanque‐fossuo, C.n. ; Dahle, S.E.; Buchman, S.R.; Rivkah Isseroff, R. (2017). "Deferoxamine: potential novel topical therapeutic for chronic wounds." British Journal of Dermatology (4): 1056-1059.
dc.identifier.issn0007-0963
dc.identifier.issn1365-2133
dc.identifier.urihttps://hdl.handle.net/2027.42/136734
dc.publisherWiley Periodicals, Inc.
dc.publisherNovartis
dc.titleDeferoxamine: potential novel topical therapeutic for chronic wounds
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelDermatology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/136734/1/bjd14956.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/136734/2/bjd14956_am.pdf
dc.identifier.doi10.1111/bjd.14956
dc.identifier.sourceBritish Journal of Dermatology
dc.identifier.citedreferenceDonneys A, Weiss DM, Deshpande SS et al. Localized deferoxamine injection augments vascularity and improves bony union in pathologic fracture healing after radiotherapy. Bone 2013; 52: 318 â 25.
dc.identifier.citedreferenceDoulias PT, Christoforidis S, Brunk UT, Galaris D. Endosomal and lysosomal effects of desferrioxamine: protection of HeLa cells from hydrogen peroxideâ induced DNA damage and induction of cellâ cycle arrest. Free Radic Biol Med 2003; 35: 719 â 28.
dc.identifier.citedreferenceNovartis. Desferal R/Deferoxamine Mesylate for Injection. East Hanover, NJ: Novartis, 2011.
dc.identifier.citedreferenceWenk J, Foitzik A, Achterberg V et al. Selective pickâ up of increased iron by deferoxamineâ coupled cellulose abrogates the ironâ driven induction of matrixâ degrading metalloproteinase 1 and lipid peroxidation in human dermal fibroblasts in vitro: a new dressing concept. J Invest Dermatol 2001; 116: 833 â 9.
dc.identifier.citedreferenceGlotzbach JP, Wong VW, Gurtner GC. Neovascularization in diabetes. Expert Rev Endocrinol Metab 2010; 5: 99 â 111.
dc.identifier.citedreferenceFernandezâ Real JM, Lopezâ Bermejo A, Ricart W. Crossâ talk between iron metabolism and diabetes. Diabetes 2002; 51: 2348 â 54.
dc.identifier.citedreferenceSindrilaru A, Peters T, Wieschalka S et al. An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. J Clin Invest 2011; 121: 985 â 97.
dc.identifier.citedreferenceRam M, Singh V, Kumawat S et al. Deferoxamine modulates cytokines and growth factors to accelerate cutaneous wound healing in diabetic rats. Eur J Pharmacol 2015; 764: 9 â 21.
dc.identifier.citedreferenceWang C, Cai Y, Zhang Y et al. Local injection of deferoxamine improves neovascularization in ischemic diabetic random flap by increasing HIFâ 1α and VEGF expression. PLOS ONE 2014; 9: e100818.
dc.identifier.citedreferenceDuscher D, Neofytou E, Wong VW et al. Transdermal deferoxamine prevents pressureâ induced diabetic ulcers. Proc Natl Acad Sci USA 2015; 112: 94 â 9.
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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