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Protein Adsorption Switch Constructed by a Pillar[5]arene‐Based Host–Guest Interaction
dc.contributor.authorXiao, Xuan
dc.contributor.authorNie, Guanrong
dc.contributor.authorZhang, Xiaoyan
dc.contributor.authorTian, Demei
dc.contributor.authorLi, Haibing
dc.date.accessioned2017-06-16T20:09:17Z
dc.date.available2017-06-16T20:09:17Z
dc.date.issued2016-01
dc.identifier.citationXiao, Xuan; Nie, Guanrong; Zhang, Xiaoyan; Tian, Demei; Li, Haibing (2016). "Protein Adsorption Switch Constructed by a Pillar[5]arene‐Based Host–Guest Interaction." Chemistry – A European Journal 22(3): 941-945.
dc.identifier.issn0947-6539
dc.identifier.issn1521-3765
dc.identifier.urihttps://hdl.handle.net/2027.42/137280
dc.description.abstractThe interfacial properties of solid substrates are of importance for protein adsorption. Herein, we report a reversible protein adsorption switch based on the host–guest interaction of the butoxy pillar[5]arene and adipic acid. By the detector of the contact angle (CA), atomic force microscopy (AFM), and luminoscope on the silicon substrate, the intelligent protein switch exhibits excellent adsorptivity for BSA and switch performance by pH regulation.Natural design: Learning from natural biological switches, we present the example of a new protein adsorption switch successfully designed by pH adjustment based on the host–guest reversible system of the butoxy pillar[5]arene (WP5) and adipic acid (see scheme). The intelligent protein switch exhibits excellent adsorptivity for BSA and switch performance by pH regulation.
dc.publisherWiley Periodicals, Inc.
dc.subject.otherhost–guest systems
dc.subject.otherbovine serum albumin
dc.subject.otherpH reversible switch
dc.subject.otherpillar[5]arene
dc.subject.otherproteins
dc.titleProtein Adsorption Switch Constructed by a Pillar[5]arene‐Based Host–Guest Interaction
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelChemistry
dc.subject.hlbtoplevelScience
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/137280/1/chem201504076-sup-0001-misc_information.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/137280/2/chem201504076.pdf
dc.identifier.doi10.1002/chem.201504076
dc.identifier.sourceChemistry – A European Journal
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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