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The Cortisol Awakening Response and Depressive Symptomatology: The Moderating Role of Sleep and Gender

dc.contributor.authorVargas, Ivan
dc.contributor.authorMayer, Stefanie
dc.contributor.authorLopez‐duran, Nestor
dc.date.accessioned2017-10-05T18:16:25Z
dc.date.available2018-11-01T16:42:00Zen
dc.date.issued2017-08
dc.identifier.citationVargas, Ivan; Mayer, Stefanie; Lopez‐duran, Nestor (2017). "The Cortisol Awakening Response and Depressive Symptomatology: The Moderating Role of Sleep and Gender." Stress and Health 33(3): 199-210.
dc.identifier.issn1532-3005
dc.identifier.issn1532-2998
dc.identifier.urihttps://hdl.handle.net/2027.42/138213
dc.description.abstractThe association between depression and the cortisol awakening response (CAR) has been widely examined, yet the results are mixed and factors responsible for such inconsistencies are poorly understood. The current study investigated whether the link between depressive symptomatology and CAR varied as a function of two such factors: sleep and gender. The sample included 58 young adults (30 females; Mageâ =â 18.7; SDageâ =â 0.91). Participants completed the Beck Depression Inventory as well as the Consensus Sleep Diary to assess depressive symptomatology and daily sleep patterns, respectively. Participants also provided four salivary cortisol samples (0, 30, 45 and 60â min after awakening) during two consecutive weekdays. Results demonstrated that greater depressive symptoms were associated with a greater CAR but only when depressive symptoms were linked to a shorter sleep time. In addition, gender significantly moderated the association between depressive symptoms and CAR. While greater depressive symptoms were associated with an elevated CAR among females, they were associated with a blunted CAR among males. These findings provide some insight into potential mechanisms linking depressive symptomatology and CAR, and suggest that future studies examining CAR as a biomarker of depression should account for differences in sleep and gender. Copyright © 2016 John Wiley & Sons, Ltd.
dc.publisherAmerican Psychiatric Association
dc.publisherWiley Periodicals, Inc.
dc.subject.othersleep
dc.subject.othergender
dc.subject.otherHPAâ axis
dc.subject.othercortisol awakening response
dc.subject.otherdepressive symptoms
dc.titleThe Cortisol Awakening Response and Depressive Symptomatology: The Moderating Role of Sleep and Gender
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelMedicine (General)
dc.subject.hlbsecondlevelMiddle Eastern, Near Eastern and North African Studies
dc.subject.hlbsecondlevelPhilosophy
dc.subject.hlbsecondlevelPublic Health
dc.subject.hlbtoplevelHealth Sciences
dc.subject.hlbtoplevelHumanities
dc.subject.hlbtoplevelSocial Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/138213/1/smi2691_am.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/138213/2/smi2691.pdf
dc.identifier.doi10.1002/smi.2691
dc.identifier.sourceStress and Health
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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