Improving antiretroviral therapy adherence in resourceâ limited settings at scale: a discussion of interventions and recommendations
dc.contributor.author | Haberer, Jessica E. | |
dc.contributor.author | Sabin, Lora | |
dc.contributor.author | Amico, K. Rivet | |
dc.contributor.author | Orrell, Catherine | |
dc.contributor.author | Galárraga, Omar | |
dc.contributor.author | Tsai, Alexander C. | |
dc.contributor.author | Vreeman, Rachel C. | |
dc.contributor.author | Wilson, Ira | |
dc.contributor.author | Sam‐agudu, Nadia A. | |
dc.contributor.author | Blaschke, Terrence F. | |
dc.contributor.author | Vrijens, Bernard | |
dc.contributor.author | Mellins, Claude A. | |
dc.contributor.author | Remien, Robert H. | |
dc.contributor.author | Weiser, Sheri D. | |
dc.contributor.author | Lowenthal, Elizabeth | |
dc.contributor.author | Stirratt, Michael J. | |
dc.contributor.author | Sow, Papa Salif | |
dc.contributor.author | Thomas, Bruce | |
dc.contributor.author | Ford, Nathan | |
dc.contributor.author | Mills, Edward | |
dc.contributor.author | Lester, Richard | |
dc.contributor.author | Nachega, Jean B. | |
dc.contributor.author | Bwana, Bosco Mwebesa | |
dc.contributor.author | Ssewamala, Fred | |
dc.contributor.author | Mbuagbaw, Lawrence | |
dc.contributor.author | Munderi, Paula | |
dc.contributor.author | Geng, Elvin | |
dc.contributor.author | Bangsberg, David R. | |
dc.date.accessioned | 2017-10-05T18:17:47Z | |
dc.date.available | 2018-04-02T18:03:22Z | en |
dc.date.issued | 2017-01 | |
dc.identifier.citation | Haberer, Jessica E.; Sabin, Lora; Amico, K. Rivet; Orrell, Catherine; Galárraga, Omar ; Tsai, Alexander C.; Vreeman, Rachel C.; Wilson, Ira; Sam‐agudu, Nadia A. ; Blaschke, Terrence F.; Vrijens, Bernard; Mellins, Claude A.; Remien, Robert H.; Weiser, Sheri D.; Lowenthal, Elizabeth; Stirratt, Michael J.; Sow, Papa Salif; Thomas, Bruce; Ford, Nathan; Mills, Edward; Lester, Richard; Nachega, Jean B.; Bwana, Bosco Mwebesa; Ssewamala, Fred; Mbuagbaw, Lawrence; Munderi, Paula; Geng, Elvin; Bangsberg, David R. (2017). "Improving antiretroviral therapy adherence in resourceâ limited settings at scale: a discussion of interventions and recommendations." Journal of the International AIDS Society 20(1): n/a-n/a. | |
dc.identifier.issn | 1758-2652 | |
dc.identifier.issn | 1758-2652 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/138283 | |
dc.description.abstract | Introduction: Successful populationâ level antiretroviral therapy (ART) adherence will be necessary to realize both the clinical and prevention benefits of antiretroviral scaleâ up and, ultimately, the end of AIDS. Although many people living with HIV are adhering well, others struggle and most are likely to experience challenges in adherence that may threaten virologic suppression at some point during lifelong therapy. Despite the importance of ART adherence, supportive interventions have generally not been implemented at scale. The objective of this review is to summarize the recommendations of clinical, research, and public health experts for scalable ART adherence interventions in resourceâ limited settings.Methods: In July 2015, the Bill and Melinda Gates Foundation convened a meeting to discuss the most promising ART adherence interventions for use at scale in resourceâ limited settings. This article summarizes that discussion with recent updates. It is not a systematic review, but rather provides practical considerations for programme implementation based on evidence from individual studies, systematic reviews, metaâ analyses, and the World Health Organization Consolidated Guidelines for HIV, which include evidence from randomized controlled trials in lowâ and middleâ income countries. Interventions are categorized broadly as education and counselling; information and communication technologyâ enhanced solutions; healthcare delivery restructuring; and economic incentives and social protection interventions. Each category is discussed, including descriptions of interventions, current evidence for effectiveness, and what appears promising for the near future. Approaches to intervention implementation and impact assessment are then described.Results and discussion: The evidence base is promising for currently available, effective, and scalable ART adherence interventions for resourceâ limited settings. Numerous interventions build on existing health care infrastructure and leverage available resources. Those most widely studied and implemented to date involve peer counselling, adherence clubs, and short message service (SMS). Many additional interventions could have an important impact on ART adherence with further development, including standardized counselling through multiâ media technology, electronic dose monitoring, decentralized and differentiated models of care, and livelihood interventions. Optimal targeting and tailoring of interventions will require improved adherence measurement.Conclusions: The opportunity exists today to address and resolve many of the challenges to effective ART adherence, so that they do not limit the potential of ART to help bring about the end of AIDS. | |
dc.publisher | Wiley Periodicals, Inc. | |
dc.publisher | Taylor & Francis | |
dc.subject.other | HIV | |
dc.subject.other | antiretroviral therapy adherence | |
dc.subject.other | interventions | |
dc.subject.other | resourceâ limited settings | |
dc.title | Improving antiretroviral therapy adherence in resourceâ limited settings at scale: a discussion of interventions and recommendations | |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | |
dc.subject.hlbsecondlevel | Microbiology and Immunology | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.description.peerreviewed | Peer Reviewed | |
dc.contributor.affiliationum | Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, MI, USA | |
dc.contributor.affiliationother | Department of Health Services, Policy and Practice, Brown University School of Public Health, Providence, RI, USA | |
dc.contributor.affiliationother | Department of Medicine, Harvard Medical School, Boston, MA, USA | |
dc.contributor.affiliationother | Department of Global Health, Center for Global Health and Department, Boston University School of Public Health, Boston, MA, USA | |
dc.contributor.affiliationother | Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, and Department of Medicine, University of Cape Town, Cape Town, South Africa | |
dc.contributor.affiliationother | Department of Medicine and Clinical Pharmacology, Stanford University School of Medicine, Stanford, CA, USA | |
dc.contributor.affiliationother | Institute of Human Virology and Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA | |
dc.contributor.affiliationother | Clinical Department, Institute of Human Virology Nigeria, Abuja, Nigeria | |
dc.contributor.affiliationother | Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya | |
dc.contributor.affiliationother | Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA | |
dc.contributor.affiliationother | Chester M. Pierce, MD Division of Global Psychiatry, Massachusetts General Hospital, Boston, MA, USA | |
dc.contributor.affiliationother | Massachusetts General Hospital Global Health, Boston, MA, USA | |
dc.contributor.affiliationother | Oregon Health & Sciences Universityâ Portland State University School of Public Health, Portland, OR, USA | |
dc.contributor.affiliationother | Division of HIV, Infectious Disease and Global Medicine, San Francisco General Hospital, Department of Medicine, University of California, San Francisco, CA, USA | |
dc.contributor.affiliationother | HIV Care Research Program, Medical Research Council, Uganda Virus Research Institute, Entebbe, Uganda | |
dc.contributor.affiliationother | Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada | |
dc.contributor.affiliationother | Columbia University School of Social Work & School of International and Public Affairs, New York, NY, USA | |
dc.contributor.affiliationother | Department of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda | |
dc.contributor.affiliationother | Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA | |
dc.contributor.affiliationother | Division of Infectious Diseases, Department of Medicine, University of British Columbia | |
dc.contributor.affiliationother | Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada | |
dc.contributor.affiliationother | Department of HIV/AIDS, World Health Organization, Geneva, Switzerland | |
dc.contributor.affiliationother | The Arcady Group, LLC, Richmond, VA, USA | |
dc.contributor.affiliationother | Department of Infectious diseases, University of Dakar, Dakar, Sénégal | |
dc.contributor.affiliationother | Bill and Melinda Gates Foundation, Seattle, WA, USA | |
dc.contributor.affiliationother | Division of AIDS Research, National Institute of Mental Health, Bethesda, MD, USA | |
dc.contributor.affiliationother | Departments of Pediatrics and Epidemiology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA | |
dc.contributor.affiliationother | Division of HIV, ID and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA | |
dc.contributor.affiliationother | HIV Center for Clinical and Behavioral Studies, NYSPI and Department of Psychiatry, Columbia; University, New York, NY, USA | |
dc.contributor.affiliationother | WestRock Healthcare, Sion, Switzerland | |
dc.contributor.affiliationother | Department of Biostatistics, University of Liège, Liège, Wallonia, Belgium | |
dc.description.bitstreamurl | https://deepblue.lib.umich.edu/bitstream/2027.42/138283/1/jia21371.pdf | |
dc.identifier.doi | 10.7448/IAS.20.1.21371 | |
dc.identifier.source | Journal of the International AIDS Society | |
dc.identifier.citedreference | Einterz RM, Kimaiyo S, Mengech HN, Khwaâ Otsyula BO, Esamai F, Quigley F, et al. Responding to the HIV pandemic: the power of an academic medical partnership. Acad Med. 2007; 82 ( 8 ): 812 â 18. | |
dc.identifier.citedreference | Boyer S, Clerc I, Bonono Câ R, Marcellin F, Bilé Pâ C, Ventelou B. Nonâ adherence to antiretroviral treatment and unplanned treatment interruption among people living with HIV/AIDS in Cameroon: individual and healthcare supplyâ related factors. Social Sci Med. 2011; 72 ( 8 ): 1383 â 92. | |
dc.identifier.citedreference | Von Korff M, Gruman J, Schaefer J, Curry SJ, Wagner EH. Collaborative management of chronic illness. Ann Int Med. 1997; 127 ( 12 ): 1097 â 102. | |
dc.identifier.citedreference | Mathewos B, Birhan W, Kinfe S, Boru M, Tiruneh G, Addis Z, et al. Assessment of knowledge, attitude and practice towards post exposure prophylaxis for HIV among health care workers in Gondar, North West Ethiopia. BMC Public Health. 2013; 13 ( 1 ): 1. | |
dc.identifier.citedreference | Nabukeeraâ Barungi N, Elyanu P, Asire B, Katureebe C, Lukabwe I, Namusoke E, et al. Adherence to antiretroviral therapy and retention in care for adolescents living with HIV from 10 districts in Uganda. BMC Infect Dis. 2015; 15: 520. | |
dc.identifier.citedreference | Tiruneh YM, Wilson IB. What time is it? Adherence to antiretroviral therapy in Ethiopia. AIDS Behav. 2016; 20: 2662 â 73. | |
dc.identifier.citedreference | Katende D, Mutungi G, Baisley K, Biraro S, Ikoona E, Peck R, et al. Readiness of Ugandan health services for the management of outpatients with chronic diseases. Trop Med Int Health. 2015; 20 ( 10 ): 1385 â 95. | |
dc.identifier.citedreference | Dutta A, Barker C, Kallarakal A. The HIV treatment gap: estimates of the financial resources needed versus available for scaleâ up of antiretroviral therapy in 97 countries from 2015 to 2020. Plos Med. 2015; 12 ( 11 ): e1001907. | |
dc.identifier.citedreference | Kredo T, Ford N, Adeniyi FB, Garner P. Decentralising HIV treatment in lowerâ and middleâ income countries. Cochrane Database Syst Rev. 2013; 6: CD009987. | |
dc.identifier.citedreference | Barnabas RV, van Rooyen H, Tumwesigye E, Murnane PM, Baeten JM, Humphries H, et al. Initiation of antiretroviral therapy and viral suppression after home HIV testing and counselling in KwaZuluâ Natal, South Africa, and Mbarara district, Uganda: a prospective, observational intervention study. Lancet HIV. 2014; 1 ( 2 ): e68 â e76. | |
dc.identifier.citedreference | Herlihy JM, Hamomba L, Bonawitz R, Goggin CE, Sambambi K, Mwale J, et al. Integration of PMTCT and antenatal services improves combination antiretroviral therapy (cART) uptake for HIVâ positive pregnant women in southern Zambiaâ A prototype for Option B+? J Acquir Immune Defic Syndr. 2017;22. | |
dc.identifier.citedreference | Brust JC, Shah NS, Scott M, Chaiyachati K, Lygizos M, Van Der Merwe TL, et al. Integrated, homeâ based treatment for MDRâ TB and HIV in rural South Africa: an alternate model of care [Perspectives]. Int J TB Lung Dis. 2012; 16 ( 8 ): 998 â 1004. | |
dc.identifier.citedreference | Braitstein P, Siika A, Hogan J, Kosgei R, Sang E, Sidle J, et al. A clinicianâ nurse model to reduce early mortality and increase clinic retention among highâ risk HIVâ infected patients initiating combination antiretroviral treatment. J Int AIDS Soc. 2012; 15 ( 1 ): 7. | |
dc.identifier.citedreference | Mani A, Mullainathan S, Shafir E, Zhao J. Poverty impedes cognitive function. Science. 2013; 341 ( 6149 ): 976 â 80. | |
dc.identifier.citedreference | Ssewamala FM, Karimli L, Torsten N, Wang JS, Han CK, Ilic V, et al. Applying a familyâ level economic strengthening intervention to improve education and healthâ related outcomes of schoolâ going AIDSâ orphaned children: lessons from a randomized experiment in Southern Uganda. Prev Sci. 2016; 17 ( 1 ): 134 â 43. | |
dc.identifier.citedreference | Cluver LD, Hodes RJ, Sherr L, Orkin FM, Meinck F, Lim Ah Ken P, et al. Social protection: potential for improving HIV outcomes among adolescents. J Int AIDS Soc. 2015; 18 ( Suppl 6 ): 20260. | |
dc.identifier.citedreference | UNICEF. Integrated social protection systemsâ enhancing equity for children: UNICEF social protection strategic framework. UNICEF; 2012. | |
dc.identifier.citedreference | Galarraga O, Genberg BL, Martin RA, Barton Laws M, Wilson IB. Conditional economic incentives to improve HIV treatment adherence: literature review and theoretical considerations. AIDS Behav. 2013; 17 ( 7 ): 2283 â 92. | |
dc.identifier.citedreference | Operario D, Kuo C, Sosaâ Rubi SG, Galarraga O. Conditional economic incentives for reducing HIV risk behaviors: integration of psychology and behavioral economics. Health Psychol. 2013; 32 ( 9 ): 932 â 40. | |
dc.identifier.citedreference | Fiszbein A, Schady N, Ferreira FHG, Grosh M, Kelleher N, Olinto P, et al. Conditional cash transfers: a world bank policy research report. Washington, DC: The World Bank; 2009. | |
dc.identifier.citedreference | Haushofer J, Shapiro J. The shortâ term impact of unconditional cash transfers to the poor: experimental evidence from Kenya. 2016. | |
dc.identifier.citedreference | Baird S, McIntosh C, Ã zler B. Cash or condition? Evidence from a cash transfer experiment. Quarterly J Econ. 2011;qjr032. | |
dc.identifier.citedreference | McNairy ML, Gachuhi AB, Lamb MR, Nuwagabaâ Biribonwoha H, Burke S, Ehrenkranz P, et al. The Link4Health study to evaluate the effectiveness of a combination intervention strategy for linkage to and retention in HIV care in Swaziland: protocol for a cluster randomized trial. Implement Sci. 2015; 10 ( 1 ): 1. | |
dc.identifier.citedreference | Han CK, Ssewamala FM, Wang JS. Family economic empowerment and mental health among AIDSâ affected children living in AIDSâ impacted communities: evidence from a randomised evaluation in southwestern Uganda. J Epidemiol Community Health. 2013; 67 ( 3 ): 225 â 30. | |
dc.identifier.citedreference | Zullo AR, Caine K, Galarraga O. The dollars and sense of economic incentives to modify HIVâ related behaviours. J Int AIDS Soc. 2015; 18: 20724. | |
dc.identifier.citedreference | Elâ Sadr W, Branson B, Beauchamp G. Effect of financial incentives on linkage to care and viral suppression: HPTN 065. Seattle: CROI; 2015. | |
dc.identifier.citedreference | Mills E, Adhyrahu A, Karlan D. Unconditional cash grants for people living with HIV/AIDS in Uganda: a randomized trial. In: Innovations for Poverty Action. 2016. | |
dc.identifier.citedreference | Kalichman SC, Cherry C, Amaral C, White D, Kalichman MO, Pope H, et al. Health and treatment implications of food insufficiency among people living with HIV/AIDS, Atlanta, Georgia. J Urban Health. 2010; 87 ( 4 ): 631 â 41. | |
dc.identifier.citedreference | Young S, Wheeler AC, McCoy SI, Weiser SD. A review of the role of food insecurity in adherence to care and treatment among adult and pediatric populations living with HIV and AIDS. AIDS Behav. 2014; 18 ( 5 ): 505 â 15. | |
dc.identifier.citedreference | Singer AW, Weiser SD, McCoy SI. Does food insecurity undermine adherence to antiretroviral therapy? A systematic review. AIDS Behav. 2015; 19 ( 8 ): 1510 â 26. | |
dc.identifier.citedreference | Weiser SD, Tuller DM, Frongillo EA, Senkungu J, Mukiibi N, Bangsberg DR. Food insecurity as a barrier to sustained antiretroviral therapy adherence in Uganda. Plos One. 2010; 5 ( 4 ): e10340. | |
dc.identifier.citedreference | Weiser SD, Yuan C, Guzman D, Frongillo EA, Riley ED, Bangsberg DR, et al. Food insecurity and HIV clinical outcomes in a longitudinal study of urban homeless and marginally housed HIVâ infected individuals. Aids. 2013; 27 ( 18 ): 2953 â 58. | |
dc.identifier.citedreference | UNAIDS. Food and Nutrition. Geneva, Switzerland: The Joint United Nations Programme on HIV/AIDS; 2014. | |
dc.identifier.citedreference | Weiser SD, Palar K, Frongillo EA, Tsai AC, Kumbakumba E. Longitudinal assessment of associations between food insecurity, antiretroviral adherence and HIV treatment outcomes in rural Uganda. AIDS. 2014; 28 ( 1 ): 115. | |
dc.identifier.citedreference | Ivers LC, Chang Y, Jerome JG, Freedberg KA. Food assistance is associated with improved body mass index, food security and attendance at clinic in an HIV program in central Haiti: a prospective observational cohort study. AIDS Res Ther. 2010; 7 ( 1 ): 1. | |
dc.identifier.citedreference | De Pee S, Grede N, Mehra D, Bloem MW. The enabling effect of food assistance in improving adherence and/or treatment completion for antiretroviral therapy and tuberculosis treatment: a literature review. AIDS Behav. 2014; 18 ( 5 ): 531 â 41. | |
dc.identifier.citedreference | Weiser SD, Hatcher AM, Hufstedler LL, Weke E, Dworkin SL, Bukusi EA, et al. Changes in health and antiretroviral adherence among HIVâ infected adults in Kenya: qualitative longitudinal findings from a livelihood intervention. AIDS Behav. 2016;1â 13. | |
dc.identifier.citedreference | Tsai AC, Hatcher AM, Bukusi EA, Weke E, Hufstedler LL, Dworkin SL, et al. A livelihood intervention to reduce the stigma of HIV in rural Kenya: longitudinal qualitative study. AIDS Behav. 2017; 21 ( 1 ): 248 â 60. | |
dc.identifier.citedreference | Zakaras JM, Weiser SD, Hatcher AM, Weke E, Burger RL, Cohen CR, et al. A qualitative investigation of the impact of a livelihood intervention on gendered power and sexual risk behaviors among HIVâ positive adults in rural Kenya. Arch Sexual Behav. 2016;1â 13. | |
dc.identifier.citedreference | Biosca O, Brown H. Boosting health insurance coverage in developing countries: do conditional cash transfer programmes matter in Mexico? Health Policy Plan. 2015; 30 ( 2 ): 155 â 62. | |
dc.identifier.citedreference | Hernándezâ Romieu AC Del Rio C Hernándezâ à vila JE Lopezâ Gatell H, Izazolaâ Licea JA, Zuniga PU, et al. CD4 counts at entry to HIV care in mexico for patients under the â universal antiretroviral treatment program for the uninsured population,â 2007â 2014. Plos One. 2016; 11 ( 3 ): e0152444. | |
dc.identifier.citedreference | Luz PM, Girouard MP, Grinsztejn B, Freedberg KA, Veloso VG, Losina E, et al. Survival benefits of antiretroviral therapy in Brazil: a modelâ based analysis.. J Int AIDS Soc. 2016; 19 ( 1 ). | |
dc.identifier.citedreference | Wilson IB, Youn B, Lee Y, Shireman T, Galarraga O, Rana A. Implementation of antiretroviral therapy improved between 2001 and 2010 in the US. In: 11th international conference on hiv treatment and prevention adherence; May 2016; Fort Lauderdale, FL. | |
dc.identifier.citedreference | Wilson IB, Bangsberg DR, Shen J, Simoni JM, Reynolds NR, Goggin K, et al. Heterogeneity among studies in rates of decline of ART adherence over time: results from the MACH14 study. J Acquir Immune Defic Syndr. 2013; 64 ( 5 ): 448. | |
dc.identifier.citedreference | Sabin L, DeSilva MB, Halim N, Kuchukhidze JT, Gifford AL, Chemusto H, editors, et al. Out of the bubble (and into the fire?): challenges encountered implementing a mHealthâ based HIV treatment adherence study among HIVâ positive pregnant and postpartum women in Uganda. In: 11th International Conference on HIV Treatment and Prevention Adherence; 2016 May; Fort Lauderdale, FL. | |
dc.identifier.citedreference | Chesney MA The elusive gold standard. Future perspectives for HIV adherence assessment and intervention. J Acquir Immune Defic Syndr. 2006; 43 ( Suppl 1 ): S149 â 55. | |
dc.identifier.citedreference | Genberg BL, Wilson IB, Bangsberg DR, Arnsten J, Goggin K, Remien RH, et al. Patterns of antiretroviral therapy adherence and impact on HIV RNA among patients in North America. AIDS. 2012; 26 ( 11 ): 1415. | |
dc.identifier.citedreference | Levine AJ, Hinkin CH, Marion S, Keuning A, Castellon SA, Lam MM, et al. Adherence to antiretroviral medications in HIV: differences in data collected via selfâ report and electronic monitoring. Health Psychol. 2006; 25 ( 3 ): 329. | |
dc.identifier.citedreference | Amico KR, Mehrotra M, Avelinoâ Silva VI, McMahan V, Veloso VG, Anderson P, et al. Selfâ reported recent PrEP dosing and drug detection in an open label PrEP study. AIDS Behav. 2016;1â 6. | |
dc.identifier.citedreference | Williams AB, Amico KR, Bova C, Womack JA. A proposal for quality standards for measuring medication adherence in research. AIDS Behav. 2013; 17 ( 1 ): 284 â 97. | |
dc.identifier.citedreference | Feldman B, Fredericksen R, Crane P, Safren S, Mugavero M, Willig JH, et al. Evaluation of the singleâ item selfâ rating adherence scale for use in routine clinical care of people living with HIV. AIDS Behav. 2013; 17 ( 1 ): 307 â 18. | |
dc.identifier.citedreference | Simoni JM, Kurth AE, Pearson CR, Pantalone DW, Merrill JO, Frick PA. Selfâ report measures of antiretroviral therapy adherence: A review with recommendations for HIV research and clinical management. AIDS Behav. 2006; 10 ( 3 ): 227 â 45. | |
dc.identifier.citedreference | Nieuwkerk PT, Oort FJ. Selfâ reported adherence to antiretroviral therapy for HIVâ 1 infection and virologic treatment response: a metaâ analysis. J Acquir Immune Defic Syndr. 2005; 38 ( 4 ): 445 â 48. | |
dc.identifier.citedreference | Kagee A, Nel A. Assessing the association between selfâ report items for HIV pill adherence and biological measures. AIDS Care. 2012; 24 ( 11 ): 1448 â 52. | |
dc.identifier.citedreference | Haberer JE, Kiwanuka J, Nansera D, Ragland K, Mellins C, Bangsberg DR. Multiple measures reveal antiretroviral adherence successes and challenges in HIVâ infected Ugandan children. Plos One. 2012; 7 ( 5 ): e36737. | |
dc.identifier.citedreference | Haberer JE, Kiwanuka J, Nansera D, Muzoora C, Hunt PW, So J, et al. Realâ time adherence monitoring of antiretroviral therapy among HIVâ infected adults and children in rural Uganda.. AIDS. 2013; 27 ( 13 ). | |
dc.identifier.citedreference | Johnson AM, Copas AJ, Erens B, Mandalia S, Fenton K, Korovessis C, et al. Effect of computerâ assisted selfâ interviews on reporting of sexual HIV risk behaviours in a general population sample: a methodological experiment. AIDS. 2001; 15 ( 1 ): 111 â 15. | |
dc.identifier.citedreference | Adebajo S, Obianwu O, Eluwa G, Vu L, Oginni A, Tun W, et al. Comparison of audio computer assisted selfâ interview and faceâ toâ face interview methods in eliciting HIVâ related risks among men who have sex with men and men who inject drugs in Nigeria. Plos One. 2014; 9 ( 1 ): e81981. | |
dc.identifier.citedreference | Pocock SJ, Abdalla M. The hope and the hazards of using compliance data in randomized controlled trials. Stat Med. 1998; 17 ( 3 ): 303 â 17. | |
dc.identifier.citedreference | Okatch H, Beiter K, Eby J, Chapman J, Marukutira T, Tshume O, et al. Brief report: apparent antiretroviral overâ adherence by pill count is associated with HIV treatment failure in adolescents. J Acquir Immune Defic Syndr. 2016. | |
dc.identifier.citedreference | Bangsberg DR, Hecht FM, Charlebois ED, Zolopa AR, Holodniy M, Sheiner L, et al. Adherence to protease inhibitors, HIVâ 1 viral load, and development of drug resistance in an indigent population. AIDS. 2000; 14 ( 4 ): 357 â 66. | |
dc.identifier.citedreference | Bisson GP, Gross R, Bellamy S, Chittams J, Hislop M, Regensberg L, et al. Pharmacy refill adherence compared with CD4 count changes for monitoring HIVâ infected adults on antiretroviral therapy. Plos Med. 2008; 5 ( 5 ): e109. | |
dc.identifier.citedreference | World Health Oranization. Meeting report on assessment of world health organization HIV drug resistance early warning indicators: report of the early warning indicator advisory panel meeting. Geneva, Switzerland: World Health Organization; 2011. | |
dc.identifier.citedreference | Blaschke TF, Osterberg L, Vrijens B, Urquhart J. Adherence to medications: insights arising from studies on the unreliable link between prescribed and actual drug dosing histories. Annu Rev Pharmacol Toxicol. 2012; 52: 275 â 301. | |
dc.identifier.citedreference | Gill CJ, Sabin LL, Hamer DH, Keyi X, Jianbo Z, Li T, et al. Importance of dose timing to achieving undetectable viral loads. AIDS Behav. 2010; 14 ( 4 ): 785 â 93. | |
dc.identifier.citedreference | Gandhi M, Yang Q, Bacchetti P, Huang Y. Short communication: A lowâ cost method for analyzing nevirapine levels in hair as a marker of adherence in resourceâ limited settings. AIDS Res Human Retro. 2014; 30 ( 1 ): 25 â 28. | |
dc.identifier.citedreference | Calcagno A, Motta I, Milia MG, Rostagno R, Simiele M, Libanore V, et al. Dried plasma/blood spots for monitoring antiretroviral treatment efficacy and pharmacokinetics: a crossâ sectional study in rural Burundi. Br J Clin Pharmacol. 2015; 79 ( 5 ): 801 â 08. | |
dc.identifier.citedreference | Hendrix CW, Andrade A, Bumpus NN, Kashuba AD, Marzinke MA, Moore A, et al. Dose frequency ranging pharmacokinetic study of tenofovirâ emtricitabine after directly observed dosing in healthy volunteers to establish adherence benchmarks (HPTN 066). AIDS Res Human Retro. 2016; 32 ( 1 ): 32 â 43. | |
dc.identifier.citedreference | Maman D, Zeh C, Mukui I, Kirubi B, Masson S, Opolo V, et al. Cascade of HIV care and population viral suppression in a highâ burden region of Kenya. AIDS. 2015; 29 ( 12 ): 1557 â 65. | |
dc.identifier.citedreference | Boyer S, March L, Kouanfack C, Labordeâ Balen G, Marino P, Aghokeng AF, et al. Monitoring of HIV viral load, CD4 cell count, and clinical assessment versus clinical monitoring alone for antiretroviral therapy in lowâ resource settings (Stratall ANRS 12110/ESTHER): a costâ effectiveness analysis. Lancet Infect Dis. 2013; 13 ( 7 ): 577 â 86. | |
dc.identifier.citedreference | Deming WE The PDSA Cycle: the W. Edwards Deming Institute; 2016. Available from: https://www.deming.org/theman/theories/pdsacycle | |
dc.identifier.citedreference | Kilo CM A framework for collaborative improvement: lessons from the Institute for Healthcare Improvement’s Breakthrough Series. Qual Manag Health Care. 1998; 6 ( 4 ): 1 â 13. | |
dc.identifier.citedreference | Zullig LL, Bosworth HB. Selecting, adapting, and sustaining programs in health care systems. J Multidiscip Healthc. 2015; 8: 199. | |
dc.identifier.citedreference | Nachega JB, Hislop M, Nguyen H, Dowdy DW, Chaisson RE, Regensberg L, et al. Antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in southern Africa. J Acquir Immune Defic Syndr. 2009; 51 ( 1 ): 65 â 71. | |
dc.identifier.citedreference | Jobanputra K, Parker LA, Azih C, Okello V, Maphalala G, Kershberger B, et al. Factors associated with virological failure and suppression after enhanced adherence counselling, in children, adolescents and adults on antiretroviral therapy for HIV in Swaziland. Plos One. 2015; 10 ( 2 ): e0116144. | |
dc.identifier.citedreference | Haberer JE Actionable adherence monitoring to optimise intervention. Lancet HIV. 2017; 4 ( 1 ): e5 â e6. | |
dc.identifier.citedreference | Elliot E, Amara A, Jackson A, Moyle G, Else L, Khoo S, et al. Dolutegravir and elvitegravir plasma concentrations following cessation of drug intake. J Antimicrob Chemother. 2016; 71 ( 4 ): 1031 â 36. | |
dc.identifier.citedreference | Volberding PA, Deeks SG. Antiretroviral therapy and management of HIV infection. Lancet. 2010; 376 ( 9734 ): 49 â 62. | |
dc.identifier.citedreference | Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, et al. Prevention of HIVâ 1 infection with early antiretroviral therapy. N Engl J Med. 2011; 365 ( 6 ): 493 â 505. | |
dc.identifier.citedreference | Granich RM, GIlks CF, Dye C, De Cock KM, Williams BG. Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet. 2009; 373: 48 â 57. | |
dc.identifier.citedreference | UNAIDS. Global AIDS Update 2016. Geneva, Switzerland: The Joint United Nations Programme on HIV/AIDS; 2016. | |
dc.identifier.citedreference | Adakun SA, Siedner MJ, Muzoora C, Haberer JE, Tsai AC, Hunt PW, et al. Higher baseline CD4 cell count predicts treatment interruptions and persistent viremia in patients initiating ARVs in rural Uganda. J Acquir Immune Defic Syndr. 2013; 62 ( 3 ): 317 â 21. | |
dc.identifier.citedreference | Haas AD, Msukwa MT, Egger M, Tenthani L, Tweya H, Jahn A, et al. Adherence to antiretroviral therapy during and after pregnancy: cohort study on women receiving care in Malawi’s option B+ program. Clin Infect Dis. 2016; 63 ( 9 ): 1227 â 35. | |
dc.identifier.citedreference | Haberer JE, Musinguzi N, Yap Boum I, Siedner MJ, Mocello AR, Hunt PW, et al. Duration of antiretroviral therapy adherence interruption is associated with risk of virologic rebound as determined by realâ time adherence monitoring in rural Uganda. J Acquir Immune Defic Syndr. 2015; 70 ( 4 ): 386 â 92. | |
dc.identifier.citedreference | Arnsten JH, Demas PA, Farzadegan H, Grant RW, Gourevitch MN, Chang CJ, et al. Antiretroviral therapy adherence and viral suppression in HIVâ infected drug users: comparison of selfâ report and electronic monitoring. Clin Infect Dis. 2001; 33 ( 8 ): 1417 â 23. | |
dc.identifier.citedreference | Lowâ Beer S, Yip B, O’Shaughnessy MV, Hogg RS, Montaner JS. Adherence to triple therapy and viral load response. J Acquir Immune Defic Syndr. 2000; 23 ( 4 ): 360 â 61. | |
dc.identifier.citedreference | Paterson DL, Swindells S, Mohr J, Brester M, Vergis EN, Squier C, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Int Med. 2000; 133 ( 1 ): 21 â 30. | |
dc.identifier.citedreference | UNAIDS. 90â 90â 90: an ambitious treatment target to help end the AIDS epidemic. Geneva, Switzerland: The Joint United Nations Programme on HIV/AIDS; 2014. | |
dc.identifier.citedreference | Vrijens B, De Geest S, Hughes DA, Przemyslaw K, Demonceau J, Ruppar T, et al. A new taxonomy for describing and defining adherence to medications. Br J Clin Pharmacol. 2012; 73 ( 5 ): 691 â 705. | |
dc.identifier.citedreference | Kaufman MR, Cornish F, Zimmerman RS, Johnson BT. Health behavior change models for HIV prevention and AIDS care: practical recommendations for a multilevel approach. J Acquir Immune Defic Syndr. 2014; 66 ( Suppl 3 ): S250 â 8. | |
dc.identifier.citedreference | Wakabi W Low ART adherence in Africa. Lancet Infect Dis. 2008; 8 ( 2 ): 94. | |
dc.identifier.citedreference | Chaiyachati KH, Ogbuoji O, Price M, Suthar AB, Negussie EK, Barnighausen T. Interventions to improve adherence to antiretroviral therapy: a rapid systematic review. AIDS. 2014; 28 ( Suppl 2 ): S187 â 204. | |
dc.identifier.citedreference | Barth RE, Van Der Loeff MF, Schuurman R, Hoepelman AI, Wensing AM. Virological followâ up of adult patients in antiretroviral treatment programmes in subâ Saharan Africa: a systematic review. Lancet Infect Dis. 2010; 10 ( 3 ): 155 â 66. | |
dc.identifier.citedreference | Keiser O, MacPhail P, Boulle A, Wood R, Schechter M, Dabis F, et al. Accuracy of WHO CD4 cell count criteria for virological failure of antiretroviral therapy. Trop Med Int Health. 2009; 14 ( 10 ): 1220 â 25. | |
dc.identifier.citedreference | WHO. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach. Geneva, Switzerland: World Health Organization; 2016. | |
dc.identifier.citedreference | Jain V, Byonanebye DM, Amanyire G, Kwarisiima D, Black D, Kabami J, et al. Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+ Tâ cell counts above 350 cells/mul in rural Uganda. AIDS. 2014; 28 ( 15 ): 2241 â 49. | |
dc.identifier.citedreference | Bere T, Nyamayaro P, Magidson JF, Chibanda D, Chingono A, Munjoma R, et al. Cultural adaptation of a cognitiveâ behavioural intervention to improve adherence to antiretroviral therapy among people living with HIV/AIDS in Zimbabwe: nzira Itsva. J Health Psychol. 2016;1359105315626783. | |
dc.identifier.citedreference | Futterman D, Shea J, Besser M, Stafford S, Desmond K, Comulada WS, et al. Mamekhaya: a pilot study combining a cognitiveâ behavioral intervention and mentor mothers with PMTCT services in South Africa. AIDS Care. 2010; 22 ( 9 ): 1093 â 100. | |
dc.identifier.citedreference | Simoni JM, Wiebe JS, Sauceda JA, Huh D, Sanchez G, Longoria V, et al. A preliminary RCT of CBTâ AD for adherence and depression among HIVâ positive Latinos on the USâ Mexico border: the Nuevo Dia study. AIDS Behav. 2013; 17 ( 8 ): 2816 â 29. | |
dc.identifier.citedreference | Holstad MM, Essien EJ, Ekong E, Higgins M, Teplinskiy I, Adewuyi MF. Motivational groups support adherence to antiretroviral therapy and use of risk reduction behaviors in HIV positive Nigerian women: a pilot study. African J Repro Health. 2012; 16: 3. | |
dc.identifier.citedreference | Taiwo BO, Idoko JA, Welty LJ, Otoh I, Job G, Iyaji PG, et al. Assessing the viorologic and adherence benefits of patientâ selected HIV treatment partners in a resourceâ limited setting. J Acquir Immune Defic Syndr. 2010; 54 ( 1 ): 85 â 92. | |
dc.identifier.citedreference | Wouters E, van Damme W, van Loon F, van Rensburg D, Meulemans H. Publicâ sector ART in the Free State Province, South Africa: community support as an important determinant of outcome. Social Sci Med. 2009; 69 ( 8 ): 1177 â 85. | |
dc.identifier.citedreference | Luqueâ Fernandez MA, van Cutsem G, Goemaere E, Hilderbrand K, Schomaker M, Mantangana N, et al. Effectiveness of patient adherence groups as a model of care for stable patients on antiretroviral therapy in Khayelitsha, Cape Town, South Africa. Plos One. 2013; 8 ( 2 ): e56088. | |
dc.identifier.citedreference | Chang LW, Kagaayi J, Nakigozi G, Ssempijja V, Packer AH, Serwadda D, et al. Effect of peer health workers on AIDS care in Rakai, Uganda: a clusterâ randomized trial. Plos One. 2010; 5 ( 6 ): e10923. | |
dc.identifier.citedreference | Hickey MD, Salmen CR, Omollo D, Mattah B, Fiorella KJ, Geng EH, et al. Pulling the network together: quasiâ experimental trial of a patientâ defined support network intervention for promoting engagement in HIV care and medication adherence on Mfangano Island, Kenya. J Acquir Immune Defic Syndr. 2015. | |
dc.identifier.citedreference | Kiweewa FM, Wabwire D, Nakibuuka J, Mubiru M, Bagenda D, Musoke P, et al. Noninferiority of a taskâ shifting HIV care and treatment model using peer counselors and nurses among Ugandan women initiated on ART: evidence from a randomized trial. J Acquir Immune Defic Syndr. 2013; 63 ( 4 ): e125 â e32. | |
dc.identifier.citedreference | Pearson CR, Micek MA, Simoni JM, Hoff PD, Matediana E, Martin DP, et al. Randomized control trial of peerâ delivered, modified directly observed therapy for HAART in Mozambique. J Acquir Immune Defic Syndr. 2007; 46 ( 2 ): 238 â 44. | |
dc.identifier.citedreference | Robbins RN, Mellins CA, Leu CS, Rowe J, Warne P, Abrams EJ, et al. Enhancing lay counselor capacity to improve patient outcomes with multimedia technology. AIDS Behav. 2015; 19 ( Suppl 2 ): 163 â 76. | |
dc.identifier.citedreference | Ikeda JM, Barrios R, Lopez Lopez JB, Hearst N. SMS messaging improves treatment outcome among the HIVâ positive Mayan population in rural Guatemala. In: International AIDS Conference; 2012 Jul 22â 27; Washington (DC); 2012. | |
dc.identifier.citedreference | Popâ Eleches C, Thirumurthy H, Habyarimana JP Zivin JG Goldstein MP, De Walque D, et al. Mobile phone technologies improve adherence to antiretroviral treatment in a resourceâ limited setting: a randomized controlled trial of text message reminders. AIDS. 2011; 25 ( 6 ): 825 â 34. | |
dc.identifier.citedreference | Da Costa TM, Barbosa BJ, Gomes E Costa DA, Sigulem D, De Fatima Marin H, Filho AC, et al. Results of a randomized controlled trial to assess the effects of a mobile SMSâ based intervention on treatment adherence in HIV/AIDSâ infected Brazilian women and impressions and satisfaction with respect to incoming messages. Int J Med Inform. 2012; 81 ( 4 ): 257 â 69. | |
dc.identifier.citedreference | Lester RT, Ritvo P, Mills EJ, Kariri A, Karanja S, Chung MH, et al. Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial. Lancet. 2010; 376 ( 9755 ): 1838 â 45. | |
dc.identifier.citedreference | Maduka O, Tobinâ West West. Adherence counseling and reminder text messages improve uptake of antiretroviral therapy in a tertiary hospital in Nigeria. Niger J Clin Pract. 2013; 16 ( 3 ): 302 â 08. | |
dc.identifier.citedreference | De Bruin M, Hospers HJ, van Breukelen GJ, Kok G, Koevoets WM, Prins JM. Electronic monitoringâ based counseling to enhance adherence among HIVâ infected patients: a randomized controlled trial. Health Psychol. 2010; 29 ( 4 ): 421 â 28. | |
dc.identifier.citedreference | Sabin L, DeSilva MB, Gill CJ, Zhong L, Vian T, Xie W, et al. Improving adherence to antiretroviral therapy with triggered realâ time text message reminders: the china adherence through technology study. J Acquir Immune Defic Syndr. 2015; 69 ( 5 ): 551 â 59. | |
dc.identifier.citedreference | Haberer JE, Musiimenta A, Atukunda EC, Musinguzi N, Wyatt MA, Ware NC, et al. Short message service (SMS) reminders and realâ time adherence monitoring improve antiretroviral therapy adherence in rural Uganda. AIDS. 2016; 30 ( 8 ): 1295. | |
dc.identifier.citedreference | Orrell C, Cohen K, Mauff K, Bangsberg DR, Maartens G, Wood R. A randomized controlled trial of realâ time electronic adherence monitoring with text message dosing reminders in people starting firstâ line antiretroviral therapy. J Acquir Immune Defic Syndr. 2015; 70 ( 5 ): 495 â 502. | |
dc.identifier.citedreference | Puttkammer N, Zeliadt S, Balan JG, Baseman J, Destine R, Domerçant JW, et al. Development of an electronic medical record based alert for risk of HIV treatment failure in a lowâ resource setting. Plos One. 2014; 9 ( 11 ): e112261. | |
dc.identifier.citedreference | Selke HM, Kimaiyo S, Sidle JE, Vedanthan R, Tierney WM, Shen C, et al. Taskâ shifting of antiretroviral delivery from health care workers to persons living with HIV/AIDS: clinical outcomes of a communityâ based program in Kenya. J Acquir Immune Defic Syndr. 2010; 55 ( 4 ): 483 â 90. | |
dc.identifier.citedreference | Bermudez LG, Jennings L, Ssewamala FM, Nabunya P, Mellins C, McKay M. Equity in adherence to antiretroviral therapy among economicallyâ vulnerable adolescents living with HIV in Uganda. AIDS Care. 2016; 28: 83 â 91. | |
dc.identifier.citedreference | Linnemayr S, Stecher C, Mukasa B. Behavioral economic incentives to improve adherence to antiretrovirals: early evidence from a randomized controlled trial in Uganda. AIDS. 2017 [E pub]. | |
dc.identifier.citedreference | Solomon SS, Srikrishnan AK, Vasudevan CK, Anand S, Kumar MS, Balakrishnan P, et al. Voucher incentives improve linkage to and retention in care among HIVâ infected drugs users in Chennai, India. Clin Infect Dis. 2014;ciu324. | |
dc.identifier.citedreference | Byron E, Gillespie S, Nangami M. Integrating nutrition security with treatment of people living with HIV: lessons from Kenya. Food Nutr Bull. 2008; 29 ( 2 ): 87 â 97. | |
dc.identifier.citedreference | Cantrell RA, Sinkala M, Megazinni K, Lawsonâ Marriott S, Washington S, Chi BH, et al. A pilot study of food supplementation to improve adherence to antiretroviral therapy among food insecure adults in Lusaka, Zambia.. J Acquir Immune Defic Syndr. 2008; 49 ( 2 ). | |
dc.identifier.citedreference | Martinez H, Palar K, Linnemayr S, Smith A, Derose KP, Ramirez B, et al. Tailored nutrition education and food assistance improve adherence to HIV antiretroviral therapy: evidence from Honduras. AIDS Behav. 2014; 18 ( Suppl 5 ): S566 â 77. | |
dc.identifier.citedreference | Weiser SD, Bukusi EA, Steinfeld RL, Frongillo EA, Weke E, Dworkin SL, et al. Shamba Maisha: randomized controlled trial of an agricultural and finance intervention to improve HIV health outcomes. AIDS. 2015; 29 ( 14 ): 1889 â 94. | |
dc.identifier.citedreference | Viswanathan M, Kahwati LC, Golin CE, Blalock SJ, Cokerâ Schwimmer E, Posey R, et al. Medication therapy management interventions in outpatient settings: a systematic review and metaâ analysis. JAMA Intern Med. 2015; 175 ( 1 ): 76 â 87. | |
dc.identifier.citedreference | Chisholmâ Burns MA, Lee JK, Spivery CA Slack M Herrier RN, Hallâ Lipsy E, et al. US pharmacistsâ effect as team members on patient care: systematic review and metaâ analyses. Med Care. 2010; 48 ( 10 ): 923 â 33. | |
dc.identifier.citedreference | Thompson MA, Mugavero MJ, Amico KR, Cargill VA, Chang LW, Gross R, et al. Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidenceâ based recommendations from an International Association of Physicians in AIDS Care panel. Ann Intern Med. 2012; 156 ( 11 ): 817 â 33. | |
dc.identifier.citedreference | Perazzo J, Reyes D, Webel A. A systematic review of health literacy interventions for people living with HIV. AIDS Behav. 2016 [Epub]. | |
dc.identifier.citedreference | Whitlock EP, Orleans T, Pender N, Allan J. Behavioral counseling interventions: an evidenceâ based approach. Am J Prev Med. 2002; 22 ( 4 ): 267 â 84. | |
dc.identifier.citedreference | Beck JS Cognitive behavior therapy: basics and beyond. Guilford Press; 2011. | |
dc.identifier.citedreference | Safren SA, O’Cleirigh C, Tan JY, Raminani SR, Reilly LC, Otto MW, et al. A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBTâ AD) in HIVâ infected individuals. Health Psychol. 2009; 28 ( 1 ): 1 â 10. | |
dc.identifier.citedreference | Newcomb ME, Bedoya CA, Blashill AJ, Lerner JA, O’Cleirigh C, Pinkston MM, et al. Description and demonstration of cognitive behavioral therapy to enhance antiretroviral therapy adherence and treat depression in HIVâ infected adults. Cogn Behav Pract. 2015; 22 ( 4 ): 430 â 38. | |
dc.identifier.citedreference | Easthall C, Song F, Bhattacharya D. A metaâ analysis of cognitiveâ based behaviour change techniques as interventions to improve medication adherence. BMJ Open. 2013; 3 ( 8 ): e002749. | |
dc.identifier.citedreference | Papas RK, Sidle JE, Martino S, Baliddawa JB, Songole R, Omolo OE, et al. Systematic cultural adaptation of cognitiveâ behavioral therapy to reduce alcohol use among HIVâ infected outpatients in western Kenya. AIDS Behav. 2010; 14 ( 3 ): 669 â 78. | |
dc.identifier.citedreference | Rollnick S, Miller WR, Butler CC, Aloia MS. Motivational interviewing in health care: helping patients change behavior. Taylor & Francis; 2009. | |
dc.identifier.citedreference | Hill S, Kavookjian J. Motivational interviewing as a behavioral intervention to increase HAART adherence in patients who are HIVâ positive: a systematic review of the literature. AIDS Care. 2012; 24 ( 5 ): 583 â 92. | |
dc.identifier.citedreference | Bofill L, Weiss SM, Lucas M, Bordato A, Dorigo A, Fernandezâ Cabanillas G, et al. Motivational interviewing among HIV health care providers challenges and opportunities to enhance engagement and retention in care in buenos aires, Argentina. J Int AIDS Soc. 2015; 14 ( 6 ): 491 â 96. | |
dc.identifier.citedreference | Mbuagbaw L, Ye C, Thabane L. Motivational interviewing for improving outcomes in youth living with HIV. Cochrane Database Syst Rev. 2012; 9: CD009748. | |
dc.identifier.citedreference | Dewing S, Mathews C, Schaay N, Cloete A, Simbayi L, Louw J. Improving the counselling skills of lay counsellors in antiretroviral adherence settings: a cluster randomised controlled trial in the Western Cape, South Africa. AIDS Behav. 2015; 19 ( 1 ): 157 â 65. | |
dc.identifier.citedreference | Rongkavilit C, Naarâ King S, Kaljee LM, Panthong A, Koken JA, Bunupuradah T, et al. Applying the informationâ motivationâ behavioral skills model in medication adherence among Thai youth living with HIV: a qualitative study. AIDS Patient Care Stds. 2010; 24 ( 12 ): 787 â 94. | |
dc.identifier.citedreference | Peltzer K, Friendâ Du Preez N, Ramlagan S, Anderson J. Antiretroviral treatment adherence among HIV patients in KwaZuluâ Natal, South Africa. BMC Public Health. 2010; 10 ( 1 ): 1. | |
dc.identifier.citedreference | Dewing S, Mathews C, Cloete A, Schaay N, Shah M, Simbayi L, et al. From research to practice: lay adherence counsellorsâ fidelity to an evidenceâ based intervention for promoting adherence to antiretroviral treatment in the Western cape, South Africa. AIDS Behav. 2013; 17 ( 9 ): 2935 â 45. | |
dc.identifier.citedreference | Koken JA, Naarâ King S, Umasa S, Parsons JT, Saengcharnchai P, Phanuphak P, et al. A crossâ cultural threeâ step process model for assessing motivational interviewing treatment fidelity in Thailand. Health Educ Behav. 2012; 39 ( 5 ): 574 â 82. | |
dc.identifier.citedreference | Beach MC, Roter DL, Saha S, Korthuis PT, Eggly S, Cohn J, et al. Impact of a brief patient and provider intervention to improve the quality of communication about medication adherence among HIV patients. Patient Educ Counsel. 2015; 98 ( 9 ): 1078 â 83. | |
dc.identifier.citedreference | Golin CE, Earp J, Tien Hâ C, Stewart P, Porter C, Howie L. A 2â arm, randomized, controlled trial of a motivational interviewingâ based intervention to improve adherence to antiretroviral therapy (ART) among patients failing or initiating ART. J Acquir Immune Defic Syndr. 2006; 42 ( 1 ): 42. | |
dc.identifier.citedreference | Gwadz M, Cleland CM, Applegate E, Belkin M, Gandhi M, Salomon N, et al. Behavioral intervention improves treatment outcomes among HIVâ infected individuals who have delayed, declined, or discontinued antiretroviral therapy: a randomized controlled trial of a novel intervention. AIDS Behav. 2015; 19 ( 10 ): 1801 â 17. | |
dc.identifier.citedreference | Foster C, McDonald S, Frize G, Ayers S, Fidler S. â Payment by Resultsâ â financial incentives and motivational interviewing, adherence interventions in young adults with perinatally acquired HIVâ 1 infection: a pilot program. AIDS Patient Care Stds. 2014; 28 ( 1 ): 28 â 32. | |
dc.identifier.citedreference | Navarro J, Perez M, Curran A, Burgos J, Feijoo M, Torrella A, et al. Impact of an adherence program to antiretroviral treatment on virologic response in a cohort of multitreated and poorly adherent HIVâ infected patients in Spain. AIDS Patient Care Stds. 2014; 28 ( 10 ): 537 â 42. | |
dc.identifier.citedreference | Ingersoll KS, Farrellâ Carnahan L, Cohenâ Filipic J, Heckman CJ, Ceperich SD, Hettema J, et al. A pilot randomized clinical trial of two medication adherence and drug use interventions for HIV+ crack cocaine users. Drug Alcohol Depend. 2011; 116 ( 1 ): 177 â 87. | |
dc.identifier.citedreference | Goggin K, Gerkovich MM, Williams KB, Banderas JW, Catley D, Berkleyâ Patton J, et al. A randomized controlled trial examining the efficacy of motivational counseling with observed therapy for antiretroviral therapy adherence. AIDS Behav. 2013; 17 ( 6 ): 1992 â 2001. | |
dc.identifier.citedreference | Bainâ Brickley D, Butler LM, Kennedy GE, Rutherford GW. Interventions to improve adherence to antiretroviral therapy in children with HIV infection. Cochrane Database Syst Rev. 2011;12. | |
dc.identifier.citedreference | Bateganya MH, Amanyeiwe U, Roxo U, Dong M. Impact of support groups for people living with HIV on clinical outcomes: a systematic review of the literature. J Acquir Immune Defic Syndr. 2015; 68 ( Suppl 3 ): S368 â 74. | |
dc.identifier.citedreference | Foster S, Nakamanya S, Kyomuhangi R, Amurwon J, Namara G, Amuron B, et al. The experience of â medicine companionsâ to support adherence to antiretroviral therapy: quantitative and qualitative data from a trial population in Uganda. AIDS Care. 2010; 22 ( S1 ): 35 â 43. | |
dc.identifier.citedreference | Lees S, Kielmann K, Cataldo F, Gitauâ Mburu Mburu. Understanding the linkages between informal and formal care for people living with HIV in subâ Saharan Africa. Glob Public Health. 2012; 7 ( 10 ): 1109 â 19. | |
dc.identifier.citedreference | Mwai GW, Mburu G, Torpey K, Frost P, Ford N, Seeley J. Role and outcomes of community health workers in HIV care in subâ Saharan Africa: a systematic review. J Int AIDS Soc. 2013; 16: 18586. | |
dc.identifier.citedreference | Nachega JB, Chaisson RE, Goliath R, Efron A, Chaudhary MA, Ram M, et al. Randomized controlled trial of trained patientâ nominated treatment supporters providing partial directly observed antiretroviral therapy. AIDS. 2010; 24 ( 9 ): 1273 â 80. | |
dc.identifier.citedreference | Reisner MSL, Mimiaga MJ, Skeer MM, Perkovich MB, Johnson MCV, Safren SA. A review of HIV antiretroviral adherence and intervention studies among HIVâ infected youth. Topics HIV Med. 2009; 17 ( 1 ): 14. | |
dc.identifier.citedreference | van Tam V, Larsson M, Pharris A, Diedrichs B, Nguyen HP, Nguyen CTK, et al. Peer support and improved quality of life among persons living with HIV on antiretroviral treatment: a randomised controlled trial from northeastern Vietnam. Health Qual Life Outcomes. 2012; 10 ( 1 ): 1. | |
dc.identifier.citedreference | Wouters E, van Damme W, van Rensburg D, Masquillier C, Meulemans H. Impact of communityâ based support services on antiretroviral treatment programme delivery and outcomes in resourceâ limited countries: a synthetic review. BMC Health Serv Res. 2012; 12: 194. | |
dc.identifier.citedreference | Grimsrud A, Sharp J, Kalombo C, Bekker LG, Myer L. Implementation of communityâ based adherence clubs for stable antiretroviral therapy patients in Cape Town, South Africa. J Int AIDS Soc. 2015; 18: 19984. | |
dc.identifier.citedreference | Wilkinson LS ART adherence clubs: A longâ term retention strategy for clinically stable patients receiving antiretroviral therapy. Southern African J HIV Med. 2013; 14 ( 2 ): 48. | |
dc.identifier.citedreference | Rosenberg NE, van Lettow M, Tweya H, Kapitoâ Tembo A, Bourdon CM, Cataldo F, et al. Improving PMTCT uptake and retention services through novel approaches in peerâ based familyâ supported care in the clinic and community: a 3â arm cluster randomized trial (PURE Malawi). J Acquir Immune Defic Syndr. 2014; 67 ( 2 ): S114 â 9. | |
dc.identifier.citedreference | Samâ Agudu NA, Cornelius LJ, Okundaye JN, Adeyemi OA, Isah HO, Wiwa OM, et al. The impact of mentor mother programs on PMTCT service uptake and retentionâ inâ care at primary health care facilities in Nigeria: a prospective cohort study (MoMent Nigeria). J Acquir Immune Defic Syndr. 2014; 67 ( Suppl 2 ): S132 â 8. | |
dc.identifier.citedreference | Kyakuwa M, Hardon A, Goldstein Z. â The adopted children of ARTâ : expert clients and role tensions in ART provision in Uganda. Med Anthropol. 2012; 31 ( 2 ): 149 â 61. | |
dc.identifier.citedreference | Mutumba M, Musiime V, Tsai AC, Byaruhanga J, Kiweewa F, Bauermeister JA, et al. Disclosure of HIV status to perinatally infected adolescents in Urban Uganda: a qualitative study on timing, process, and outcomes. J Assoc Nurses AIDS Care. 2015; 26 ( 4 ): 472 â 84. | |
dc.identifier.citedreference | Mutumba M, Bauermeister JA, Musiime V, Byaruhanga J, Francis K, Snow RC, et al. Psychosocial challenges and strategies for coping with HIV among adolescents in Uganda: a qualitative study. AIDS Patient Care Stds. 2015; 29 ( 2 ): 86 â 94. | |
dc.identifier.citedreference | Remien R, Mellins CA, Robbins RN, Kelsey R, Rowe J, Warne P, et al. Masivukeni: development of a multimedia based antiretroviral therapy adherence intervention for counselors and patients in South Africa. AIDS Behav. 2013; 17 ( 6 ): 1979 â 91. | |
dc.identifier.citedreference | Asher AK, Santos Gâ M, Evans J, Dokubo EK, Lee Tâ H, Martin JN, et al. A closer look at hepatitis C clearance in HIV controllers: a response. AIDS. 2014; 28 ( 8 ): S1241 â 2. | |
dc.identifier.citedreference | Claborn KR, Fernandez A, Wray T, Ramsey S. Computerâ based HIV adherence promotion interventions: a systematic review. Transl Behav Med. 2015; 5 ( 3 ): 294 â 306. | |
dc.identifier.citedreference | Gapminder. Bubble map of cell phones (per 100 people) 2010 [cited 2017 Feb 4]. Available from: https://www.gapminder.org | |
dc.identifier.citedreference | Jongbloed K, Parmar S, Van Der Kop M, Spittal PM, Lester RT. Recent evidence for emerging digital technologies to support global HIV engagement in care. Curr HIV/AIDS Rep. 2015; 12 ( 4 ): 451 â 61. | |
dc.identifier.citedreference | Mbuagbaw L, Van Der Kop ML, Lester RT, Thirumurthy H, Popâ Eleches C, Ye C, et al. Mobile phone text messages for improving adherence to antiâ retroviral therapy (ART): an individual patient data metaâ analysis of randomised trials. BMJ Open. 2013; 3 ( 12 ): e003950. | |
dc.identifier.citedreference | Kimmerling M, Wagner G, Ghoshâ Dastidar Dastidar. Factors associated with accurate selfâ reported adherence to HIV antiretrovirals. Int J STD AIDS. 2003; 14 ( 4 ): 281 â 84. | |
dc.identifier.citedreference | Pearson CR, Simoni JM, Hoff P, Kurth AE, Martin DP. Assessing antiretroviral adherence via electronic drug monitoring and selfâ report: an examination of key methodological issues. AIDS Behav. 2007; 11 ( 2 ): 161 â 73. | |
dc.identifier.citedreference | Horvath T, Azman H, Kennedy GE, Rutherford GW. Mobile phone text messaging for promoting adherence to antiretroviral therapy in patients with HIV infection. Cochrane Database Syst Rev. 2012; 3: CD009756. | |
dc.identifier.citedreference | Finitsis DJ, Pellowski JA, Johnson BT. Text message intervention designs to promote adherence to antiretroviral therapy (ART): a metaâ analysis of randomized controlled trials. Plos One. 2014; 9 ( 2 ): e88166. | |
dc.identifier.citedreference | van Velthoven MH, Brusamento S, Majeed A, Car J. Scope and effectiveness of mobile phone messaging for HIV/AIDS care: a systematic review. Psychol Health Med. 2013; 18 ( 2 ): 182 â 202. | |
dc.identifier.citedreference | Mbuagbaw L, Thabane L, Ongoloâ Zogo P, Lester RT, Mills EJ, Smieja M, et al. The cameroon mobile phone SMS (CAMPS) trial: a randomized trial of text messaging versus usual care for adherence to antiretroviral therapy. Plos One. 2012; 7 ( 12 ): e46909. | |
dc.identifier.citedreference | Shet A, De Costa A, Kumarasamy N, Rodrigues R, Rewari BB, Ashorn P, et al. Effect of mobile telephone reminders on treatment outcome in HIV: evidence from a randomised controlled trial in India. Bmj. 2014; 349: g5978. | |
dc.identifier.citedreference | Demonceau J, Ruppar T, Kristanto P, Hughes DA, Fargher E, Kardas P, et al. Identification and assessment of adherenceâ enhancing interventions in studies assessing medication adherence through electronically compiled drug dosing histories: a systematic literature review and metaâ analysis. Drugs. 2013; 73 ( 6 ): 545 â 62. | |
dc.identifier.citedreference | Vrijens B, Urquhart J, White D. Electronically monitored dosing histories can be used to develop a medicationâ taking habit and manage patient adherence. Expert Rev Clin Pharmacol. 2014; 7 ( 5 ): 633 â 44. | |
dc.identifier.citedreference | Liu X, Lewis JJ, Zhang H, Lu W, Zhang S, Zheng G, et al. Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a clusterâ randomised trial. Plos Med. 2015; 12 ( 9 ): e1001876. | |
dc.identifier.citedreference | Mbuagbaw L, Bononoâ Momnougui RC, Thabane L, Kouanfack C, Smieja M, Ongoloâ Zogo Zogo. A framework for community ownership of a text messaging programme to improve adherence to antiretroviral therapy and clientprovider communication: a mixed methods study. BMC Health Serv Res. 2014; 14: 441. | |
dc.identifier.citedreference | Wald DS, Butt S, Bestwick JP. Oneâ way versus twoâ way text messaging on improving medication adherence: metaâ analysis of randomized trials. Am J Med. 2015; 128 ( 10 ): 1139e1 â 5. | |
dc.identifier.citedreference | Tweya H, Feldacker C, Benâ Smith A, Harries AD, Komatsu R, Jahn A, et al. Simplifying ART cohort monitoring: can pharmacy stocks provide accurate estimates of patients retained on antiretroviral therapy in Malawi? BMC Health Serv Res. 2012; 12 ( 1 ): 210. | |
dc.identifier.citedreference | Orrell C, Dipenaar R, Killa N, Tassie Jâ M, Harries AD, Wood R. Simplifying HIV cohort monitoringâ pharmacy stock records minimize resources necessary to determine retention in care. J Acquir Immune Defic Syndr. 2013; 62 ( 3 ): e106 â e8. | |
dc.identifier.citedreference | Petersen ML, LeDell E, Schwab J, Sarovar V, Gross R, Reynolds N, et al. Super learner analysis of electronic adherence data improves viral prediction and may provide strategies for selective HIV RNA monitoring. J Acquir Immune Defic Syndr. 2015; 69 ( 1 ): 109 â 18. | |
dc.identifier.citedreference | Phillips AN, Cambiano V, Nakagawa F, Bansiâ Matharu L, Sow PS, Ehrenkranz P, et al. Cost effectiveness of potential ART adherence monitoring interventions in subâ Saharan Africa. Plos One. 2016; 11 ( 12 ): e0167654. | |
dc.identifier.citedreference | Ware NC, Pisarski EE, Tam M, Wyatt MA, Atukunda E, Musiimenta A, et al. The Meanings in the messages: how SMS reminders and realâ time adherence monitoring improve antiretroviral therapy adherence in rural Uganda. AIDS. 2016; 30 ( 8 ): 1287 â 94. | |
dc.identifier.citedreference | Campbell JI, Eyal N, Musiimenta A, Haberer JE. Ethical questions in medical electronic adherence monitoring. J Gen Intern Med. 2016; 31 ( 3 ): 338 â 42. | |
dc.identifier.citedreference | Bachman Desilva M, Gifford AL, Keyi X, Li Z, Feng C, Brooks M, et al. Feasibility and acceptability of a realâ time adherence device among HIVâ positive IDU patients in China. AIDS Res Treat. 2013; 2013: 957862. | |
dc.identifier.citedreference | Lester RT Ask, don’t tellâ mobile phones to improve HIV care. N Engl J Med. 2013; 369 ( 19 ): 1867 â 68. | |
dc.identifier.citedreference | Sabin L, Vian T, Bachman Desilva M, Gifford AL, Zhong L, Xie W, et al. â It will remind me to take my doses on timeâ : views of participation in an antiretroviral therapy adherence intervention trial in China. In: 10th International Conference on HIV Treatment and Prevention Adherence; June 2015; Miami, FL. | |
dc.identifier.citedreference | Wagner EH, Austin BT, Von Korff M. Organizing care for patients with chronic illness. Milbank Q. 1996; 74 ( 4 ): 511 â 44. | |
dc.identifier.citedreference | Tsai AC, Morton SC, Mangione CM, Keeler EB. A metaâ analysis of interventions to improve care for chronic illnesses. Am J Manag Care. 2005; 11 ( 8 ): 478 â 88. | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.