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The role of nicotinamide in acne treatment
dc.contributor.authorWalocko, Frances M.
dc.contributor.authorEber, Ariel E.
dc.contributor.authorKeri, Jonette E.
dc.contributor.authorAl‐harbi, Mana A.
dc.contributor.authorNouri, Keyvan
dc.date.accessioned2017-10-23T17:31:06Z
dc.date.available2018-11-01T16:42:01Zen
dc.date.issued2017-09
dc.identifier.citationWalocko, Frances M.; Eber, Ariel E.; Keri, Jonette E.; Al‐harbi, Mana A. ; Nouri, Keyvan (2017). "The role of nicotinamide in acne treatment." Dermatologic Therapy 30(5): n/a-n/a.
dc.identifier.issn1396-0296
dc.identifier.issn1529-8019
dc.identifier.urihttps://hdl.handle.net/2027.42/138875
dc.description.abstractSafe and effective treatment options for acne vulgaris are needed to address side effects and increasing rates of antibiotic resistance from current treatments. Nicotinamide is a vitamin with potent antiâ inflammatory properties that could offer a potential treatment option. We aim to summarize the relevant literature on the role of nicotinamide in acne vulgaris and discuss the next steps necessary to move this approach into clinical practice. We searched PubMed for clinical studies using nicotinamide for treatment of acne vulgaris. We summarized the 10 studies that met our search criteria. Six of eight studies using topical nicotinamide led to a significant reduction in acne compared with the patient’s baseline or performed similarly to another standardâ ofâ care acne treatment. Both studies using an oral supplement containing nicotinamide resulted in a significant reduction in acne compared with baseline. No major adverse side effects were noted. Our review suggests that topical and oral nicotinamide has an unclear effect on acne vulgaris due to the limited nature of the available literature. Additional studies are needed comparing nicotinamide to other firstâ line acne treatments and evaluating the efficacy and side effect profile of nicotinamide over an extended period of time.
dc.publisherWiley Periodicals, Inc.
dc.subject.othervitamin B3
dc.subject.otherniacinamide
dc.subject.otherinflammatory acne
dc.subject.othernicotinamide
dc.subject.otherantibiotic resistance
dc.subject.otheracne vulgaris
dc.titleThe role of nicotinamide in acne treatment
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelDermatology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/138875/1/dth12481_am.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/138875/2/dth12481.pdf
dc.identifier.doi10.1111/dth.12481
dc.identifier.sourceDermatologic Therapy
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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