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Acute poisonings during pregnancy and in other non‐pregnant women in emergency departments of four government hospitals, Addis Ababa, Ethiopia: 2010‐2015

dc.contributor.authorEyasu, Mebrahtu
dc.contributor.authorDida, Tolesa
dc.contributor.authorWorku, Yoseph
dc.contributor.authorWorku, Solomon
dc.contributor.authorShafie, Mensur
dc.date.accessioned2017-10-23T17:31:12Z
dc.date.available2018-12-03T15:34:05Zen
dc.date.issued2017-10
dc.identifier.citationEyasu, Mebrahtu; Dida, Tolesa; Worku, Yoseph; Worku, Solomon; Shafie, Mensur (2017). "Acute poisonings during pregnancy and in other non‐pregnant women in emergency departments of four government hospitals, Addis Ababa, Ethiopia: 2010‐2015." Tropical Medicine & International Health 22(10): 1350-1360.
dc.identifier.issn1360-2276
dc.identifier.issn1365-3156
dc.identifier.urihttps://hdl.handle.net/2027.42/138882
dc.description.abstractObjectiveTo characterise acute poisonings in pregnant and non‐pregnant women treated at emergency departments of government hospitals in Addis Ababa, Ethiopia, between 2010 and 2015.MethodsAll data for acutely poisoned women were retrospectively collected from patient medical charts at the emergency departments of Saint Paul’s Hospital Millennium Medical College, Ras Desta Memorial Hospital, Yekatit 12 Hospital Medical College and Zewditu Memorial Hospital. Data were collected by extraction questionnaire and analysed using SPSSv. 20 statistical software.ResultsDuring the study period, 998 cases of acutely poisoned women were listed in the hospital registries. Of these, complete data for inclusion in the study were available for 592. 36.3% of the study participants were in the age group of 20–24, with a mean (±SD) age of 23.03 (±6.3) years. 80.9% were from Addis Ababa; 4.6% were pregnant. The mean arrival time of all cases was 4.14 h. 85.5% of all study cases were due to intentional self‐poisoning, of whom 42.1% were discharged without complications. The most common poisons were bleach and organophosphates; 25.9% of pregnant cases and 32.6% of non‐pregnant cases were poisoned by bleach; and 18.5% of pregnant cases and 18.9% of non‐pregnant cases had organophosphate poisoning. 0.7% had a history of poisoning; all were non‐pregnant women. The common route of poison exposure was oral, and the case fatality rate of organophosphate poisoning in pregnant and non‐pregnant women was 20 and 1.87%, respectively. The pre‐hospital intervention for the majority of the women was milk, in 12.0% of cases.ConclusionAcute poisoning remains a public health problem in our community. Bleach is the most common poisons. Our present findings indicate the necessity of educational programmes on preventable reasons of acute poisonings and their outcomes on pregnant and non‐pregnant women.ObjectifCaractériser les intoxications aiguës chez les femmes enceintes et non enceintes traitées dans les services d’urgence des hôpitaux gouvernementaux à Addis‐Abeba, en Ethiopie, entre 2010 et 2015.MéthodesToutes les données sur les femmes avec une intoxication aiguë ont été collectées rétrospectivement à partir des dossiers médicaux des patientes dans les services d’urgence du Collège Médical du Millénaire de l’Hôpital Saint‐Paul, de l’Hôpital Memorial de Ras Desta, du Collège Médical Hospitalier Yekatit 12 et de l’Hôpital Memorial de Zewditu. Les données ont été recueillies par extraction dans des questionnaires et analysées en utilisant le logiciel statistique SPSS v. 20.RésultatsDurant la période d’étude, 998 cas d‘intoxications aiguës chez des femmes ont été répertoriés dans les registres hospitaliers. Parmi ceux‐ci, les données complètes pour inclusion dans l’étude étaient disponibles pour 592 cas. 36,3% des participantes à l’étude étaient du groupe d’âge 20 à 24 ans, avec un âge moyen (±SD) de 23,03 (±6,3) ans. 80,9% provenaient d’Addis‐Abeba, 4,6% étaient enceintes. Le délai moyen d’arrivée de tous les cas était de 4,14 heures. 85,5% de tous les cas de l’étude étaient dus à une auto‐intoxication intentionnelle, dont 42,1% ont été libérés sans complications. Les poisons les plus courants étaient l’eau de Javel et les organophosphorés; 25,9% des cas enceintes et 32,6% des cas non enceintes avaient été intoxiqués par l’eau de Javel et 18,5% des cas enceintes et 18,9% des cas non‐enceintes l‘avaient été par des organophosphorés. 0,7% des cas avaient des antécédents d’intoxication; toutes étant des femmes non enceintes. La voie courante de l’exposition au poison était orale et le taux de létalité de l’intoxication par organophosphorés chez les femmes enceintes et non enceintes était respectivement de 20 et 1,87%. L’intervention pré hospitalière pour la majorité des femmes était avec du lait dans 12,0% des cas.ConclusionL’intoxication aiguë reste un problème de santé publique dans notre communauté. L’eau de Javel est le poison le plus courant. Nos résultats ici indiquent la nécessité de programmes éducatifs sur les causes évitables des intoxications aiguës et leurs résultats chez les femmes enceintes et non enceintes.ObjetivoCaracterizar los envenenamientos agudos en mujeres embarazadas y no embarazadas atendidas en servicios de emergencia de hospitales gubernamentales en Addis Ababa, Etiopia, entre el 2010 y el 2015.MétodosRetrospectivamente, a partir de historias clínicas, se recopilaron datos de mujeres con un envenenamiento agudo atendidas en los servicios de emergencias del Hospital Universitario de Saint Paul’s Millennium, el Hospital Ras Desta Memorial, el Hospital Universitario Yekatit 12 y el Hospital Zewditu Memorial. Los datos se recogieron mediante un cuestionario de extracción y se analizaron utilizando el software estadístico SPSS v. 20.ResultadosDurante el periodo de estudio, según los registros de los hospitales, hubo 998 casos de mujeres con envenenamiento agudo. De estos, 592 tenían datos completos podían incluirse en el estudio. 36.3% de las participantes estaban en el grupo de edad de 20‐24 años, con una desviación estándar (+DS) de 23.03 (+6.3) años. Un 80.9% eran de Addis Ababa; 4.6% estaban embarazadas. El tiempo medio de llegada de todos los casos era 4.14 horas. Un 85.5% de todos los casos de estudio se debían a un auto‐envenenamiento intencional, de los cuales 42.1% fueron dadas de alta sin complicaciones. Los venenos más comunes eran la lejía y los organofosforados; un 25.9% de los casos de embarazadas y un 32.6% de los casos de mujeres no embarazadas tenían envenenamiento por lejía y un 18.5% de las mujeres embarazadas y un 18.9% de las no embarazadas tenían envenenamiento por organofosforados. Un 0.7% tenía una historia de envenenamientos previos; todas eran mujeres no embarazadas. La ruta más común de exposición era la oral, y en este caso la tasa de letalidad por envenenamiento con organofosforados en mujeres embarazadas y no embarazadas era de 20% y 1.87%, respectivamente. La intervención pre‐hospitalaria para la mayoría de las mujeres era leche, en un 12.0% de los casos.ConclusiónEl envenenamiento agudo continúa siendo un problema de salud pública en nuestra comunidad. La lejía es el veneno más común. Nuestros hallazgos indican la necesidad de programas educativos sobre causas evitables de los envenenamientos agudos y sus resultados en mujeres embarazadas y no embarazadas.
dc.publisherWiley Periodicals, Inc.
dc.subject.otherenvenenamiento agudo
dc.subject.otheremergencia
dc.subject.otherAddis Ababa
dc.subject.otherorganofosforados
dc.subject.otherlejía
dc.subject.otheracute poisoning
dc.subject.otheremergency
dc.subject.otherAddis Ababa
dc.subject.otherbleach and organophosphate poisoning
dc.subject.otherintoxication aigüe
dc.subject.otherurgence
dc.subject.otherAddis‐Abeba
dc.subject.otherintoxication à l’eau de Javel et aux organophosphorés
dc.titleAcute poisonings during pregnancy and in other non‐pregnant women in emergency departments of four government hospitals, Addis Ababa, Ethiopia: 2010‐2015
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelMedicine (General)
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/138882/1/tmi12940.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/138882/2/tmi12940_am.pdf
dc.identifier.doi10.1111/tmi.12940
dc.identifier.sourceTropical Medicine & International Health
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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