Now showing items 101-110 of 174
Morphine self-administration, food-reinforced, and avoidance behaviors in rhesus monkeys
(Springer-Verlag, 1964-03)
1. A fixed interval-fixed ratio chain of behavior was maintained for periods as long as 6 months by intravenously administered morphine.
The interplay of steric and electronic factors affecting geometrical isomerism of diaryl ketimine derivatives
(Elsevier, 1960)
The evidence bearing on the mechanism of the Schmidt reaction with ketones is critically reexamined. It is shown that dehydration of an initially formed azidohydrin (I) to a ketiminodiazonium ion (II), which may or may not ...
Destruction of indoleacetic acid : IV. Kinetics of enzymic oxidation
(Elsevier, 1962-02)
Kinetics of enzymic oxidation of indoleacetic acid (IAA) are interpreted as indicating that the reaction has an autocatalytic, cyclical mechanism involving unstable intermediates whose formation and disappearance are ...
Microdetermination of dihydroxyacetone in biological fluids
(Elsevier, 1961-04)
Dihydroxyacetone is reacted with an excess of 2,4-dinitrophenylhydrazine. The excess reagent is removed by the addition of pyruvic acid and followed by partition between benzene and sodium bicarbonate solution. The benzene ...
Self-administration of psychoactive substances by the monkey
(Springer-Verlag, 1969-01)
A method has been developed which permits monkeys to self-administer drug solutions, at will, through indwelling intravenous catheters. Psychological dependence on the effects of a drug occurs when a naive monkey voluntarily ...
Differential actions of m and n cholinergic agonists on the brainstem activating system
(Elsevier, 1969-03)
The differential actions of i.v. arecoline and nicotine were determined on neocortical and limbic system EEG activation in acute rostral and caudal midbrain transected cats. All animals were prepared under diethyl ether ...
Acute and short-term oral toxicity of 2-n-ethylaminoethanol in rats
(Elsevier, 1969)
Acute oral doses of neutralized 2-N-ethylaminoethanol (EAE) in rats greatly increased gastric secretion, resulting in dehydration and death after 3-4 days. The effect of EAE on gastric secretion did not appear to be due ...
Amino acid content of rabbit urine and plasma
(Elsevier, 1962-03)
The content of amino acids in plasma and urine from male albino rabbits was determined by ion-exchange chromatography and compared to values for other species.In general, the amino acids present in the plasma and urine of ...
Pharmacological patterns in subcortical reinforcement behavior
(Elsevier, 1963-12)
By means of intercurrent hypothalamic positive reinforcement and tegmental negative reinforcement tests, drug actions on two different brain-stimulated behaviors were assessed simultaneously. Chlorpromazine at 2 mg/kg was ...