Now showing items 31-40 of 40
Central effects of atropine upon aversive classical conditioning in rabbits
(Springer-Verlag, 1972-12)
Rabbits were given classical discrimination conditioning with one of two tones followed by shock. In Experiment I, 40 rabbits were trained under saline, 10, 18 or 26 mg/kg atropine sulfate or 18 mg/kg methylatropine. Six ...
Acetylseco hemicholinium-3, a new choline acetyltransferase inhibitor useful in neuropharmacological studies
(Elsevier, 1973-06)
Described are the synthesis and some aspects of the pharmacology of acetylseco hemicholinium-3 (acetylseco HC-3), the acetylated open ring analogue of hemicholinium-3 (HC-3). The effects of both compounds were determined ...
Facilitation of opiate-and enkephalin-induced motor activity in the mouse by phenytoin sodium and carbamazepine
(Springer-Verlag, 1979-01)
In the first experiment, adult male Swiss-Webster mice were systemically injected with a standard dose of morphine. Compared to the influence of vehicle, the motor activity of morphine-injected mice was increased. Neither ...
Behavioural observations in gunn rats
(Springer-Verlag, 1978-01)
The Gunn rat is a hooded mutant of albino rat with various biochemical defects, including a low UDP-glucuronosyl-transferase activity. As a consequence, about half of their offspring are jaundiced from birth, due to high ...
Brain acetylcholine in morphine pellet implanted rats given naloxone
(Springer-Verlag, 1975-01)
Adult male rats were implanted with intraventricular (ivt.) brain cannulae for injection of 5 Μg of acetylseco-hemicholinium-3 (acetylseco HC-3) as a means of studying acetylcholine (ACh) utilization during morphine ...
The use of d -amphetamine pellet implantation as a model for d -amphetamine tolerance in the mouse
(Springer-Verlag, 1973-09)
The use of d -amphetamine pellet implantation as a method for producing rapid central drug tolerance was investigated. Mice were implanted with d -amphetamine pellets containing 2 mg of drug and were challenged 24 h later, ...
Rate-dependent effect of amphetamine in rats: Extension to between-subjects effect
(Springer-Verlag, 1976-01)
Following either variable-interval or fixed-interval training, 20 rats received both 0.5 and 2.0 mg/kg of amphetamine. For both schedules, amphetamine decreased response rates of high-rate subjects and increased those of ...
A reexamination of apomorphine induced stereotypy in the rat in light of self administration experiments
(Elsevier, 1979)
1. 1. Apomorphine is known to both elicit stereotypy and to support behavioral self administration. The present report examined a possible contribution of stereotypy to self administration.2. 2. Non-contingent intraperitoneal ...
Experimental variables in the effects of postsession injections of strychnine sulphate on a classically conditioned response
(Springer-Verlag, 1970-01)
Postsession strychnine injections have been shown to retard acquisition rates of the classically conditioned nictitating membrane response (CCNMR) of rabbits trained at a CS-US interval of 1000 msec. The particular interval ...