Now showing items 11-20 of 40
Effects of stress and REM sleep deprivation on the patterns of avoidance learning and brain acetylcholine in the mouse
(Springer-Verlag, 1973-12)
Pure bred DBA/2J mice were subjected to varying degrees of stress and “water tank” REM sleep deprivation using one-animal cages, large platforms and/or poles. Subsequently, the animals were studied for acquisition, short-term ...
Effects of a novel anti-aggressive agent upon two types of brain stimulated emotional behavior
(Springer-Verlag, 1976-01)
The effects of anti-agressive agent Sch 12679 were evaluated upon stable baselines of rage and predation elicited by electrical stimulation of the hypothalamus in cats. Sch 12679 depressed approach and terminal aspects of ...
Inhibition of phenylethanolamine-N-methyltransferase and brain-stimulated reward
(Springer-Verlag, 1978-01)
Three centrally active inhibitors of phenylethanolamine-N-methyl transferase (PNMT; E.C.2.1.1.28), the terminal enzyme for epinephrine biosynthesis in the brain, produced dose-related decreases in rates of responding for ...
Fenfluramine and N-ethyl amphetamine: Comparison of the reinforcing and rate-decreasing actions in the rhesus monkey
(Springer-Verlag, 1975-01)
N-ethyl amphetamine HCl (NEA) and fenfluramine HCl ( meta -trifluoromethyl N-ethyl amphetamine) were evaluated as reinforcers in rhesus monkeys that had been previously trained to press a lever using food presentations and ...
Effects of d -amphetamine, scopolamine, chlordiazepoxide and diphenylhydantoin on self-stimulation behavior and brain acetylcholine
(Springer-Verlag, 1972-03)
The effects of d-amphetamine (0.25–8), scopolamine (0.25–8), chlordiazepoxide (2.5–40), and diphenylhydantoin (25–75), given i.p. or s.c. on a mg/kg basis, were studied on self-stimulation behavior in the male albino rat. ...
Cocaine, d -amphetamine, and pentobarbital effects on responding maintained by food or cocaine in rhesus monkeys
(Springer-Verlag, 1979-09)
The effects of IM injections of cocaine, d -amphetamine, and pentobarbital were studied in rhesus monkeys whose lever-press responding was maintained under a second-order fixed-interval, fixed ratio schedule of reinforcement. ...
Psychotropic drug influences on brain acetylcholine utilization
(Springer-Verlag, 1972-12)
The cholinergic antisynthesis agent HC-3 was given intraventricularly to young male rats 20–30 days old to deplete brain acetylcholine (ACh). The rate of HC-3 induced depletion of ACh was used as an index of ACh utilization. ...
Effects of chronic lithium and rubidium administration upon experimentally induced conflict behavior
(Elsevier, 1977)
1. 1. Chronic treatment of rats with lithium chloride produced a significant reduction of shock induced suppression of feeding behavior (passive avoidance) in the rat.2. 2. Rubidium chloride, on the other hand, caused ...
Enkephalin-dopamine interactions in behavioral arousal
(Elsevier, 1979)
1. 1. Central injection of a long lasting enkephalin analog (D-Ala2-leuo-enkephalin-amide) produced a syndrome of stereotyped motor activity.2. 2. This activation syndrome was significantly reduced by two dopamine (DA) ...
Effects of various psychotomimetic agents on the eeg and acetylcholine release from the cerebral cortex of brainstem transected cats
(Elsevier, 1972-09)
The effects of i.v. administration of [Delta]9 THC, phencyclidine, the pyrrolidyl and piperidyl isomers of Ditran, and LSD-25 were determined on the spontaneous neocortical EEG and release of acetylcholine (ACh) from the ...