Now showing items 21-30 of 560
Stereochemistry in the cyclization of -azidophenylalkenes to indoles
(Elsevier, 1983)
- and --azidostilbene, -azido-[beta]-methylstilbene, and ()--azido[beta]-deuteriostyrene give indoles on thermolysis by a mechanism involving attack by a nitrene directly on the [beta] carbon atom, and not by insertion.
A structural comparison of the A and B subunits of Griffonia simplicifolia I isolectins
(Elsevier, 1984-02-15)
A structural comparison between the A and B subunits of the five tetrameric Griffonia simplicifolia I isolectins (A4, A3B, A2B2, AB3, B4) was undertaken to determine the extent of homology between the subunits. The first ...
Antagonism of the discriminative effects of ethylketazocine, cyclazocine, and nalorphine in macaques
(Springer-Verlag, 1984-09)
dl -Ethylketazocine (EKC, 0.01 mg/kg) and saline were established as discriminative stimuli for food-maintained responding in macaque monkeys. Thirty consecutive presses on a right or left lever were reinforced with food, ...
Enkephalinase: Selective inhibitors and partial characterization
(Elsevier, 1980)
There are at least two types of enzymes in brain, endopeptidases and aminopeptidases, which metabolize enkephalins. Evidence is presented to suggest that enkephalinase, an endopeptidase cleaving at the Gly-Phe bond, is ...
Intrathecal bombesin-induced inhibition of gastrointestinal transit: requirement for an intact pituitary-adrenal axis
(Elsevier, 1986-05)
The role of the pituitary-adrenal axis in the inhibition of gastrointestinal transit caused by intrathecal administration of bombesin was examined. Bombesin (0.3-10 [mu]g) slowed transit by this route in a dose-related ...
A sensitive coupled HPLC/RIA technique for separation of endorphins: Multiple forms of B-endorphin in rat pituitary intermediate vs. anterior lobe
(Elsevier, 1981-08)
A technique is described which couples High Performance Liquid Chromatography (HPLC) to radioimmuno assays (RIA), thus achieving high sensitivity with good specificity. This method allows the separation and detection of ...
Measurement of ammonia and glutamine in cell culture media by gas sensing electrodes
(Kluwer Academic Publishers; Science & Technology Letters ; Springer Science+Business Media, 1989-04)
This paper describes the use of a commercially available off-line gas sensing electrode for determination of ammonia and glutamine in cell culture media. The measurement technique was tested in different media preparations ...
A novel and efficient synthesis of the naturally occurring nucleoside doridosine
(Elsevier, 1985)
1-Methylisoguanosine was synthesized by a one-pot reaction involving a condensation of 5-amino-1-([beta]--ribofuranosyl)imidazole-4-carboxamide (1) with methyl isothiocyanate, treatment of the resulting thiourea derivative ...