Now showing items 71-80 of 100
Excitatory amino acid antagonists induce a phencyclidine-like catalepsy in pigeons: Structure-activity studies
(Elsevier, 1987-09)
The excitatory amino acid antagonists -2-amino-5-phosphonovalerate (-AP5), its isomers -(-)-AP5 and -(+)-AP5, -2-amino-4-phosphonobutyrate (AP4), -2-amino-7-phosphonoheptanoate (AP7), [beta]--aspartylaminomethylphosphonic ...
Opioid but not nonopioid stress-induced analgesia is enhanced following prenatal exposure to ethanol
(Springer-Verlag, 1985-01)
Two neurochemically distinct forms of stress-induced analgesia were examined in adult rats following prenatal ethanol exposure. Rats were exposed to ethanol during the last 2 weeks of gestation through a liquid diet presented ...
Acute effects of high-dose thyrotropin releasing hormone infusions in Alzheimer's disease
(Springer-Verlag, 1989-07)
Thyrotropin releasing hormone (TRH) was administered intravenously to ten patients with Alzheimer's Disease (AD) in a high-dose paradigm, thought to maximize central nervous system effects and potentially produce facilitation ...
Comparison of naltrexone and quaternary naltrexone after systemic and intracerebroventricular administration in pigeons
(Elsevier, 1987-06)
The behavioral effects of naltrexone and quaternary naltrexone were evaluated in two groups of pigeons. One group responded under a fixed-ratio schedule of food reinforcement and was trained to discriminate between 3.2 ...
Discriminative stimulus effects of N-substituted analogs of phencyclidine in rhesus monkeys
(Elsevier, 1982-12)
In daily sessions of a two-lever, discrete-trial, food-reinforced procedure, rhesus monkeys were trained to discriminate between subcutaneous injections of ketamine (1.0 or 1.8 mg/kg) and control injections. In tests of ...
Dopaminergic involvement in attention a novel animal model
(Elsevier, 1981)
1. 1. Adult male outbred albino mice were acutely injected with either of two dopamine (DA) agonists; Apomorphine, a receptor agonist, or Amantadine, a DA releasing agent.2. 2. Both drugs produced dose-related alterations ...
The degradation of dynorphin A in brain tissue in vivo and in vitro
(Elsevier, 1987)
The demonstration of analgesia following in vivo administration of dynorphin A (Dyn A) has been difficult. In contrast, a number of electrophysiological and behavioral effects reported with in vivo injection of Dyn A can ...
Opioid receptor subtype-specific cross-tolerance to the effects of morphine on schedule-controlled behavior in mice
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1988-10)
Key-press responding of mice was maintained under a fixed-ratio (FR) 30-response schedule of food presentation. Successive 3-min periods during which the experimental chamber was illuminated and the schedule was in effect ...
Discriminative stimulus effects of etorphine in rhesus monkeys
(Springer-Verlag, 1981-03)
Two rhesus monkeys were trained to discriminate the IM injection of etorphine (0.001 mg/kg) from saline in a task in which 20 consecutive responses on one of two levers resulted in food delivery. In both monkeys, etorphine ...
Further characterization of the extra-arcuate alpha-melanocyte stimulating hormone-like material in hypothalamus: Biochemical and anatomical studies
(Elsevier, 1986-04)
Previous studies had shown the existence of an extra-arcuate cell group in lateral hypothalamus which contains alpha-melanocyte stimulating hormone (a-MSH)-like immunoreactivity, but no other pro-opiomelanocortin (POMC) ...