Now showing items 1-10 of 620
High levels of non-activated receptors in glucocorticoid-sensitive S49wt mouse lymphoma cells incubated with dexamethasone
(Elsevier, 1994-10)
Upon agonist binding the heteromeric glucocorticoid receptor complex under goes a conformational change (receptor activation). This event involves the dissociation of a dimer of 90 kDa heat shock proteins. Whereas receptor ...
Curing reaction and product properties of polysulfones terminated with active functional groups
(Wiley Subscription Services, Inc., A Wiley Company, 1991-11-20)
The curing processes of maleimide-terminated polyether sulfone oligomers ( M n from 1100 to 3000) and ethynyl-terminated polysulfone prepolymers ( M n from 2600 to 12000) were investigated by means of DSC. The ...
Expression and regulation of cytochrome P-450I genes (CYP1A1 and CYP1A2) in the rat alimentary tract
(Elsevier, 1992-12-29)
Cytochrome P-450 (P450) enzymes in the mucosa of the alimentary tract may be involved in the activation and/or inactivation of ingested xenobiotics and procarcinogens. Since the multiple P450 enzymes have overlapping ...
Interaction of linear manno-oligosaccharides with three mannose-specific bulb lectins. Comparison with mannose/glucose-binding lectins
(Elsevier, 1992-05-22)
Three new mannose-binding lectins, isolated from daffodil (NPA), amaryllis (HHA), and snowdrop (GNA) bulbs, are capable of precipitating with a linear mannopentaose (Man[alpha]1-3Man[alpha]1-3Man[alpha]1-3Man[alpha]1-2Man). ...
Characterization of gastrin amidation in the rat and porcine antrum: comparison with the pituitary
(Elsevier, 1990-04-24)
The formation of biologically active gastrin from glycine-extended processing intermediates occurs via the action of a peptide [alpha]-amidating enzyme. The observation that gastrin exists primarily as unamidated precursors ...
Fusion of mercury a new certified standard for differential scanning calorimetry
(Elsevier, 1990-03)
From the results of adiabatic-calorimetric measurements, mercury has been certified as a standard reference material for temperature and enthalpy of fusion for differential scanning calorimetry. The fusion temperature is ...
Use of Cyclodextrin-Cholesterol Complex as a Primary Standard in Cholesterol Analysis
(Elsevier, 1993-06)
Cholesterol is an analyte commonly measured in various biological fluids. Enzymic procedures have virtually replaced the chemical methods for cholesterol determinations. Standardization of cholesterol assays often involve ...
Evaluation of amonafide in disseminated malignant melanoma
(Kluwer Academic Publishers; Springer Science+Business Media, 1993-06)
Amonafide (AMF), NSC 308847 is an investigational anticancer drug acting as a DNA intercalating agent. This paper presents results of a phase II clinical study of AMF in disseminated malignant melanoma. Twenty patients, ...
On-line multichannel Raman spectroscopic detection system for capillary zone electrophoresis
(Elsevier, 1991)
An on-line multichannel Raman spectroscopic detection system for capillary zone electrophoresis using a charge-coupled device as the detector is described. Resonant, near-resonant and non-resonant excitation Raman ...