Now showing items 61-70 of 682
Interactions of intracellular mediators of amylase secretion in permeabilized pancreatic acini
(Elsevier, 1991-01-23)
Mouse pancreatic acini were permeabilized with streptolysin O to investigate amylase secretion stimulated by various intracellular mediators and the kinetics of secretion as a function of temperature. Amylase secretion was ...
Studies on morpholinosphingolipids: Potent inhibitors of glucosylceramide synthase
(Elsevier, 1994-04-25)
Synthetic 1-morpholino-1-deoxyceramides were designed to inhibit glucosylceramide synthase. The most potent inhibitor 2a possesses the unnatural R,R-configuration of D-threo-sphingosine.
Immobilization of proteins on gold coated porous membranes via an activated self-assembled monolayer of thioctic acid
(Springer-Verlag, 1995-09)
A new methodology for efficient protein (e.g., antibodies, enzymes, etc.) immobilization on microporous nylon membranes for use in a variety of bioanalytical systems is introduced. The method utilizes an activated ...
Transferrin: A potential source of iron for oxygen free radical-mediated endothelial cell injury
(Elsevier, 1992-04)
The ability of transferrin to potentiate oxygen free radical-mediated endothelial cell injury was assessed. 51Cr-labeled endothelial cells derived from rat pulmonary arteries (RPAECs) were incubated with hydrogen peroxide ...
Expression of prodynorphin-derived peptides and mRNA in guinea-pig cortex
(Elsevier, 1993-08)
The distributions and extent of processing of four prodynorphin-derived peptides (dynorphin A (1-17), dynorphin A (1-8), dynorphin B, and [alpha]-neoendorphin) were determined in ten regions of the cortex as well as in the ...
A 1.8 Å resolution potential function for protein folding
(Wiley Subscription Services, Inc., A Wiley Company, 1990-08-15)
A general method is presented for constructing a potential function for approximate conformational calculations on globular proteins. The method involves solving a nonlinear program that seeks to adjust the potential's ...
Lubrication theory for n-layer thin-film flow with applications to multilayer extrusion and coating
(Elsevier, 1990)
Two-dimensional, n-layer isothermal flows of Newtonian liquids are analyzed by means of the Reynolds lubrication approximation (Phil. Trans. R. Soc. 177, 157, 1886). For algebraic simplicity, the coordinates are transformed ...
Nonlinear state feedback control of second-order nonminimum-phase nonlinear systems
(Elsevier, 1990-05)
The present work addresses the problem of synthesizing nonlinear state feedback controllers for second-order nonminimum-phase nonlinear systems. The concept of a first-order nonlinear all-pass is first introduced. A class ...
Determination of the chemical environment of sulphur in petroleum asphaltenes by X-ray absorption spectroscopy
(Elsevier, 1992-01)
Sulphur K-edge X-ray absorption spectra are analysed for a diverse series of petroleum asphaltenes. The spectra of the asphaltenes are interpreted by fitting with a linear superposition of model compound spectra. This ...
Structure of plane underexpanded air jets into water
(American Institute of Chemical EngineersWiley Periodiocals, Inc., 1990-06)
An experimental and numerical investigation of the structure of plane underexpanded turbulent air jets in water was conducted to characterize their structure and mixing properties. Measurements included void fraction ...