Now showing items 11-20 of 313
Probing RNA Structure with Chemical Reagents and Enzymes
(Wiley Periodicals, Inc., 2000-02)
This unit provides thorough coverage of the most useful chemical and enzyme probes that can be used to examine RNA secondary and tertiary structure. Footprinting methods are presented using dimethyl sulfate, diethyl ...
Injectable microparticle-gel system for prolonged and localized lidocaine release. I. In vitro characterization
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09-01)
Current treatment protocol for postoperative pain is to infuse anesthetic solution around nerves or into the epidural space. This clinical practice is beset by the short duration of the anesthetic effect unless the infusion ...
Oligoribonucleotides with 2′‐O‐(tert‐Butyldimethylsilyl) Groups
(Wiley Periodicals, Inc.IRL Press,, 2000-07)
The chemical synthesis of oligoribonucleotides on solid support is routinely performed via the phosphoramidite method. However, the additional 2‐OH function of the ribofuranosyl sugar requires suitable protection during ...
Determination of Binding Mode: Intercalation
(Academic PressWiley Periodicals, Inc., 2000-02)
A small molecule can be assumed to bind to DNA by intercalation between base pairs if it causes lengthening and unwinding of the DNA helix and undergoes changes in its spectral properties, such as DNA‐induced hypochromism ...
Early events of Bacillus anthracis germination identified by time-course quantitative proteomics
(WILEY-VCH Verlag, 2006-10)
Germination of Bacillus anthracis spores involves rehydration of the spore interior and rapid degradation of several of the protective layers, including the spore coat. Here, we examine the temporal changes that occur ...
Cellular Delivery of Locked Nucleic Acids (LNAs)
(Wiley Periodicals, Inc., 2002-06)
Locked nucleic acids (LNAs) are RNA derivatives that have an O‐methylene linkage between the 2 and 4 positions of the ribose. This leads to exceptionally high‐affinity binding to complementary sequences. They are synthesized ...
Low-Temperature SCR of NO with NH 3 over USY-Supported Manganese Oxide-Based Catalysts
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2003-04)
A series of catalysts of manganese oxide, manganese–cerium and iron–manganese oxide supported on USY (ultra-stable Y zeolite) were studied for the low-temperature selective catalytic reduction (SCR) of NO with ammonia in ...
Representation of Somatosensory Evoked Potentials Using Discrete Wavelet Transform
(Kluwer Academic Publishers; Springer Science+Business Media, 2002-04)
Objective. Somatosensory evoked potentials (SEP) have been shown to be a useful tool in monitoring of the central nervous system (CNS) during anaesthesia. SEP analysis is usually performed by an experienced human operator. ...
Synthetic nano-fibrillar extracellular matrices with predesigned macroporous architectures
(John Wiley & Sons, Inc., 2000-11)
Scaffolding plays a pivotal role in tissue engineering. To mimic the architecture of a natural extracellular matrix component—collagen, nona-fibrous matrices have been created with synthetic biodegradable polymers in our ...
Engineering vascular networks in porous polymer matrices
(Wiley Subscription Services, Inc., A Wiley Company, 2002-06-15)
Enhanced vascularization is critical to the treatment of ischemic tissues and the engineering of new tissues and organs. We have investigated whether sustained and localized delivery of vascular endothelial growth factor ...