Now showing items 301-310 of 313
Development of Functional Bioengineered Muscle Models and a Novel Micro-Perfusion System.
(2008)
Tissue engineering combines the principles of medical, life science, and engineering fields toward the development of biological substitutes to restore, maintain, or improve tissue function. Previous work has demonstrated ...
Perfusion Estimation in Volumetric Imaging of Ultrasound Contrast Agents.
(2009)
This dissertation presents research involving the investigation of perfusion measured using volumetric imaging of ultrasound contrast agents. Ultrasound contrast agents are micrometer-sized gas bubbles that track the blood ...
Nanochemistry for Biomedical Sensors and Contrast Agents.
(2008)
The primary focus of the work described in this dissertation is the coupling of PEBBLE (Photonic Explorers for Biomedical use by Biologically Localized Embedding) nanosensors with new sensing technologies.
Included in ...
Image Guided Respiratory Motion Analysis: Time Series and Image Registration.
(2008)
The efficacy of Image guided radiation therapy (IGRT) systems relies on accurately extracting, modeling and predicting tumor movement with imaging techniques. This thesis
investigates two key problems associated with such ...
On Improving the Effectiveness of Control Signals from Chronic Microelectrodes for Cortical Neuroprostheses.
(2009)
Using microelectrodes, we can record neural signals which can eventually be used to control cortical neuroprostheses for assisting people with spinal-cord trauma, stroke deficits, amyotrophic lateral sclerosis (ALS), and ...
Medical Ultrasound Aberration Correction via Acoustic Droplet Vaporization and Time-Reversal Acoustics.
(2009)
Time-reversal acoustics (TRA) is an alternative to standard focusing approaches in medical ultrasound. TRA records backscattered ultrasound and time-reverses it (Ψ(t) -> Ψ(−t)). Due to the time-reversal invariance of the ...
Sarcomere Dynamics During Contraction-Induced Injury to Permeabilized Single Muscle Fibers.
(2008)
A contraction-induced injury results when an activated skeletal muscle or a single fiber is stretched in a ‘lengthening contraction’. This type of injury to muscle fibers is a leading cause of the loss of mobility that is ...
An Alternative Outpatient Scheduling System: Improving the Outpatient Experience.
(2008)
Patient wait time has long been a recognized problem in modern outpatient health care delivery systems. Despite all the efforts to develop appointment rules and solutions, the problem of long patient waits persists. ...
Automated Natural-Language Processing for Integration and Functional Annotation of Complex Biological Systems.
(2008)
This dissertation discusses the use of automated natural language processing (NLP) for characterization of biomolecular events in signal transduction pathway databases. I also discuss the use of a dynamic map engine for ...
Novel Bioinformatics Approaches for MicroRNA Detection and Target Prediction.
(2009)
MicroRNAs (miRNAs) are regulators of gene expression at the post-transcriptional level. Scientists have not been able to fully unlock their therapeutic potential because their functions and mechanisms of action have not ...