Now showing items 71991-72000 of 72005
Assessment of Local Temperature Reactivity Response in Multi-Module HTGR Special Purpose Reactor
(2020-04-30)
HolosGen, LLC (HolosGen) is proposing a highly innovative microreactor concept targeting both civilian and military applications. It consists of an advanced helium-cooled gas reactor using a decoupled and electronically ...
Assessment of Variable Reflector Reactivity Envelope in Multi-Module HTGR Special Purpose Reactor
(2020-07-31)
In this report we examine the reactivity that is available in the reflectors (i.e. the reactivity
envelope) through several mechanisms that may be understood notionally as a “variable reflector”.
Specifically we assess ...
Maternal Diet Supplemented with Methyl-Donors Protects against Atherosclerosis in F1 ApoE<sup>-/-</sup> Mice
(Public Library of Science (PLoS), 2013-02-21)
Atherosclerosis is an inflammatory condition of the arterial wall mediated by cells of both innate and adaptive immunity. T lymphocytes play an important role in orchestrating the pathogenic immune response involved in the ...
Changes in adipose tissue macrophages and T cells in aging.
(Begell House, 2014-01-01)
Adipose tissue historically was believed to be an inert tissue, functioning primarily in the storage of energy and thermal homeostasis. However, recent discoveries point toward a critical role for adipocytes in endocrine ...
Potential of epigenetic therapies in non-cancerous conditions
(Frontiers, 2014-01-01)
There has been an explosion of knowledge in the epigenetics field in the past 20 years. The first epigenetic therapies have arrived in the clinic for cancer treatments. In contrast, much of the promise of epigenetic therapies ...
Novel Impressions: Prints, Textiles, and the Visual Economy in Europe, 1815-1851
(2021)
During a key transitional period within the Industrial Revolution between the conclusion of the Napoleonic Wars in 1815 and the 1851 opening of the Great Exhibition of All Nations, British and French textile designers ...
Plexins promote Hedgehog signaling through their cytoplasmic GAP activity
(eLife, 2022-09-01)
Hedgehog signaling controls tissue patterning during embryonic and postnatal development and continues to play important roles throughout life. Characterizing the full comple-ment of Hedgehog pathway components is essential ...
"Hyper-homocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model".
(2001-04-01)
Although hyperhomocysteinemia (HHcy) is a well-known risk factor for the development of cardiovascular disease, the underlying molecular mechanisms are not fully elucidated. Here we show that induction of HHcy in apoE-null ...