Now showing items 21-30 of 358
Characterization of Bioeffects on Endothelial Cells Under Acoustic Droplet Vaporization.
(2014)
An ultrasound-mediated cancer treatment called gas embolotherapy has the potential for providing selective occlusion of blood vessels for therapy. Vessel occlusion is achieved by locally vaporizing micron-sized droplets ...
Cell‐penetrating peptides: Achievements and challenges in application for cancer treatment
(Wiley Periodicals, Inc., 2014-02)
One of the major hurdles to cure cancer lies in the low potency of currently available drugs, which could eventually be solved by using more potent therapeutic macromolecules, such as proteins or genes. However, although ...
Serum albumin–protamine conjugate for biocompatible platform for targeted delivery of therapeutic macromolecules
(Wiley Periodicals, Inc., 2014-08)
A well‐defined, one‐to‐one conjugate between human serum albumin (HSA) and protamine was synthesized and characterized as a biocompatible carrier for macromolecules. In circulation, the conjugate will camouflage drug ...
Three‐dimensional polycaprolactone scaffold‐conjugated bone morphogenetic protein‐2 promotes cartilage regeneration from primary chondrocytes in vitro and in vivo without accelerated endochondral ossification
(Wiley Subscription Services, Inc., A Wiley Company, 2012-08)
As articular cartilage is avascular, and mature chondrocytes do not proliferate, cartilage lesions have a limited capacity for regeneration after severe damage. The treatment of such damage has been challenging due to the ...
Immobilized thermolysin for highly efficient production of low‐molecular‐weight protamine—An attractive cell‐penetrating peptide for macromolecular drug delivery applications
(Wiley Subscription Services, Inc., A Wiley Company, 2012-01)
Macromolecules present a remarkable potential as future therapeutics. However, their translation into clinical practice has been hampered by an inherently low bioavailability. Cell‐penetrating peptides (CPP) have been ...
Basis of bone metabolism around dental implants during osseointegration and periâ implant bone loss
(Lippincottâ RavenWiley Periodicals, Inc., 2017-07)
Despite the growing number of publications in the field of implant dentistry, there are limited studies to date investigating the biology and metabolism of bone healing around dental implants and their implications in periâ ...
Understanding the Effects of Cyclic Strain on Angiogenesis.
(2013)
The size of engineered tissues is currently limited by oxygen diffusion. Vascularization of these constructs could alleviate this problem if the cues that control blood vessel organization can be manipulated. Our laboratory ...
Nanoscale structure of type I collagen fibrils: Quantitative measurement of D‐spacing
(WILEY‐VCH Verlag, 2013-01)
This article details a quantitative method to measure the D‐periodic spacing of type I collagen fibrils using atomic force microscopy coupled with analysis using a two‐dimensional fast fourier transform approach. Instrument ...
Wrapping and dispersion of multiwalled carbon nanotubes improves electrical conductivity of protein–nanotube composite biomaterials
(Wiley Subscription Services, Inc., A Wiley Company, 2013-01)
Composites of extracellular matrix proteins reinforced with carbon nanotubes have the potential to be used as conductive biopolymers in a variety of biomaterial applications. In this study, the effect of functionalization ...
Multimodal Non-Invasive Hemodynamic Monitoring.
(2016)
Many medical conditions require health care providers to make rapid and accu- rate assessments of a patients hemodynamics to diagnose and guide treatment. Of the parameters that encompass hemodynamic evaluation (such as ...