Now showing items 21-23 of 23
The Application of Genetic, In Silico and In Vitro Tools to Elucidate the Biology of a Functional Amyloid Fiber.
(2010)
Curli are thin aggregative fimbriae produced by many Enterobacteriaceae as a structural component of biofilms. Curli share many biochemical and biophysical properties with amyloid fibers which are often associated with ...
Directed Evolution Designed to Optimize the in vivo Protein Folding Environment.
(2010)
Protein folding is assisted by molecular chaperones and folding catalysts in vivo. Understanding how chaperones are regulated and how they function in vivo may provide new avenues for developing protein folding modulators. ...
Rapid Evolution of cis-Regulatory Architecture and Activity in the Drosophila Yellow Gene.
(2012)
In the last 10 years, an increasing number of case studies showed that changes in cis-regulatory elements, mainly enhancers, are one of the main causes of altered phenotypes, but the mechanisms underlying enhancer evolution ...