Now showing items 1051-1060 of 1092
Contribution of Horizontal Gene Transfer to Virulence and Antibiotic Resistance in Pathogens Transmitted in Healthcare Facilities.
(2011)
Healthcare-associated infections (HAIs) are a significant cause of morbidity and mortality in the United States and cost up to $4.5 billion annually. Horizontal gene transfer (HGT) contributes to the evolution and emergence ...
Prevalence, Risk Factors, and Sequelae of Peripheral Neuropathy in a Population-Based Cohort of Mid-Life Women.
(2012)
Peripheral neuropathy is a well-documented complication of diabetes, yet it remains an underappreciated condition in non-diabetic individuals. Studies of neuropathy in longitudinal or population-based samples are limited. ...
The Developmental Origins of Health and Disease in Women from the Michigan Bone Health and Metabolism Study: An Examination with Longitudinal and Intergenerational Data.
(2010)
Fetal and early life experiences may be associated with development of adult chronic disease and effects may extend across generations. Epidemiologists have adapted these concepts to identify risk factors for chronic ...
Blood Pressure, Pulse Pressure, and Antihypertensive Treatment: Association with Cognitive Decline and Dementia in Elderly Mexican-Americans.
(2010)
The association between blood pressure in late life and cognitive decline has not been conclusively established and few population-based studies have examined the relationship between pulse pressure in late life and cognitive ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
Psychotropic Medication Use Among Community-Dwelling Dementia Patients: Insights from the Resources for Enhancing Alzheimer's Caregiver Health Trials.
(2011)
Currently, two types of medications, cholinesterase inhibitors and N-methyl d-aspartate (NMDA) receptor antagonists, are approved by the FDA for the treatment of cognitive dementia symptoms; however, there are no approved ...
Integrative Statistical Methods for the Analysis of Transcriptomic and and Metabolomic Data.
(2010)
Cancer research is embracing the multiple``-omics'' technologies available for global scale measurement of molecular events. Transcriptomics, as the global measure of gene expression, has been well developed through ...
Diarrheal Disease in Northwestern Ecuador: Prevalence, Pathogenicity, and Transmission of Enteric Pathogens Accross the Region.
(2012)
Over four billion episodes of diarrhea occur worldwide each year. The burden of diarrhea is particularly high for children under five years living in developing countries. One in five child-deaths are attributed to diarrhea ...
Factors Influencing Oncologists' Use of Chemotherapy in Patients at the End of Life: A Qualitative Study.
(2011)
Background: There is a trend toward increasing use of chemotherapy among cancer patients during the last two weeks of life, even though chemotherapy is expensive, produces side effects that impact quality of life, and has ...
Social patterning of chronic disease risk factors: Cross-national and within-country comparisons.
(2010)
Chronic diseases are traditionally thought to be more important in high-income countries, although most of the burden occurs in low- and middle-income countries. Despite a recent global focus on the social determinants of ...