Now showing items 11-20 of 64
Effects of chronic and acute treatment of antipsychotic drugs on calmodulin release from rat striatal membranes
(Elsevier, 1980-03)
Chronic treatment of rats with the antipsychotic drugs haloperidol and (+)-butaclamol results in supersensitivity of striatal dopamine (DA) receptors. Striatal membranes of these animals have an increased content of an ...
Behavioral effects of dynorphin -- a novel opioid neuropeptide
(Elsevier, 1980-08)
Adult male Swiss-Webster mice were implanted with permanently indwelling cannulae with tips within the lateral cerebral ventricle. The neuropeptide dynorphin was infused centrally and subjects were tested on a variety ...
Protection of cyclooxygenase activity during heme-induced destabilization
(Elsevier, 1980-05)
Sheep vesicular gland cyclooxygenase is destroyed spontaneously when incubated with only substoichiometric amounts of heme. Peroxides may participate in this destruction, since glutathione peroxidase, catalase, and phenol, ...
Effect of ethanol and of noise on reaction time in the monkey: Variation with stimulus level
(Springer-Verlag, 1980-06)
To determine whether the latency-increasing effects of ethanol were differential with respect to the intensity of the stimulus that initiated the response, three rhesus monkeys were trained on a behavioral task in which ...
A comparison of cholesteryl oleate and 19-iodocholesteryl oleate as substrates for adrenal cholesterol esterase
(Elsevier, 1980-04)
Radiolabeled 19-iodocholesterol is widely used to obtain images of human adrenals. We have shown in rats and mice that 85-95% of the radiolabel is present in the esterified form. Using rat adrenal cytosolic cholesterol ...
Vibrational spectra and normal coordinate analysis of CF 3 OF and CF 3 OCl
(John Wiley & Sons, Ltd., 1980-08)
The IR spectra (1400 cm −1 to 160 cm −1 ) of the gases at ambient temperature and the Raman spectra (below 1400 cm −1 ) of the liquids near −196°C are reported for CF 3 OF and CF 3 OCl. All fundamentals are assigned under ...
Aromatic antimony compounds. Transition metal complexes of 2,5-dimethylstibacyclopentadienyl
(Elsevier, 1980-12-23)
Hydrostannation of 2,4-hexadiyne with dibutyltin dihydride gave 1,1-dibutyl-2,5-dimethylstannole, which was converted to 2,5-dimethylstibacymantrene and to bis(2,5-dimethylstibacyclopentadienyl)iron.
Quantitation of oligosaccharides released by the [beta]-elimination reaction
(Elsevier, 1980-01-01)
A quantitative micromethod has been described for monitoring the rate and extent of the [beta]-elimination reaction as applied to O-glycosyl-glycoproteins utilizing alkaline tritiated borohydride. The procedure simultaneously ...
Behavioral effects of dynorphin1-13 in the mouse and rat: Initial observations
(Elsevier, 1980)
Dynorphin is a recently identified, pharmacologically potent endogenous opioid peptide. Heretofore it has not been characterized for its behavioral effects. The effects of centrally infused dynorphin upon a variety of ...
Y-Maze behavior after an analog of ACTH 4-9, evidence for an attentional alteration
(Springer-Verlag, 1980-11)
Adult, male, Swiss-Webster mice were injected with either control solution or various doses of a long-acting analog of ACTH 4-9. The drug produced significant alterations in performance in an equiangular Y-maze. In comparison ...