Now showing items 11-20 of 50
Determination of plasma trimetrexate levels using gas chromatography--mass spectrometry with selected-ion monitoring
(Elsevier, 1986)
Trimetrexate is a potent inhibitor of dihydrofolate reductase and has demonstrated significant antitumor activity against murine and human cell lines both in vitro and against several murine transplanted tumors. The ...
Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a
(Elsevier, 1986-05-01)
Cytochrome P-450j has been purified to electrophoretic homogeneity from hepatic microsomes of adult male rats administered ethanol and compared to the corresponding enzyme from isoniazid-treated rats. The enzymes isolated ...
Chromogranin from normal human adrenal glands: purification by monoclonal antibody affinity chromatography and partial N-terminal amino acid sequence
(Elsevier, 1986-02)
A method is presented for the purification of human chromogranin from adrenal glands obtained at autopsy. The procedure involved homogenization of whole glands in aqueous buffer, salt precipitation, affinity chromatography ...
The exchange reaction of tetramethyldipnictogens with dimethyldichalcogenides
(Elsevier, 1986-07-15)
Tetramethyldipnictogens Me4E2 (E = P, As, Sb, Bi) undergo exchange reactions with dimethyldichalcogenides Me2A2 (A = S, Se, Te) to produce the corresponding (dimethylpnicto)methylchalcogenides Me2EAMe. These compounds have ...
Lectin binding studies on murine peritoneal cells: Physicochemical characterization of the binding of lectins from Datura stramonium, Evonymus europaea, and Griffonia simplicifolia to murine peritoneal cells
(Elsevier, 1986-01)
Purified 125I-labeled lectins from Datura stramonium, Evonymus europaea, and Griffonia simplicifolia (I-B4 isolectin) were used to analyze changes in the expression of carbohydrates on the surface of resident (PC) and ...
Simultaneous determination of thymine and 5-bromouracil in DNA hydrolysates using gas chromatography--mass spectrometry with selected-ion monitoring
(Elsevier, 1986)
The gas chromatographic--mass spectrometric method using selected-ion monitoring (GC--MS--SIM) described here quantitatively determines the amount of DNA thymine replacement by 5-bromouracil (BU) after exposure to ...
Properties of the cyanobacterial coupling factor ATPase from Spirulina platensis : II. Activity of the purified and membrane-bound enzymes
(Elsevier, 1986-02-15)
Cyanobacterial (Spirulina platensis) photosynthetic membranes and isolated F1 ATPase were characterized with respect to ATP activity. The following results indicate that the regulation of expression of ATPase activity in ...
High affinity binding of substrate and effector ligands to testicular microsomal cytochrome P-450
(Elsevier, 1986-12)
The binding characteristics of substrate and effector ligands to testicular microsomal cytochrome P-450 (17[alpha]-hydroxylase/C17-20 lyase) have been investigated by difference spectroscopy. Steroid products and their ...
Silver(I) sulfide: Ag2S Heat capacity from 5 to 1000 K, thermodynamic properties, and transitions
(Elsevier, 1986-04)
The heat capacity of Ag2S has been measured by adiabatic-shield calorimetry from 5 to 1000 K. The heat capacity increases regularly up to about 445 K where the pre-transitional contribution causes rapidly rising values. ...
Report on the catalytic activity of 6-heteropolymolybdates as potential Fischer-Tropsch synthesis catalysts
(Elsevier, 1986-02-14)
Unsupported and supported decomposition products of 6-heteropolymolybdates were tested as possible Fischer-Tropsch synthesis catalysts. Depending on the heteroatom, the activity changes significantly and the best supported ...