Now showing items 31-40 of 79
Hepatic arterial chemotherapy for primary and metastatic liver cancers
(Springer-Verlag, 1989-01)
Hepatic arterial chemotherapy represents a means of selectively exposing hepatic tumor to cytotoxic agents. Although 5-fluoro-2′-deoxyuridine has been shown to generate a higher response rate in the treatment of colorectal ...
Ab initio force fields of alanine dipeptide in C5 and C7 conformations
(Elsevier, 1989-06)
We have followed up our previous ab initio calculations of the force fields and dipole-moment derivatives of glycine dipeptide in C5 and C7 conformations with similar studies of the -alanyl compound [CH3CONHCH(CH3)CONHCH3]. ...
Effect of potassium ion on the phosphorus-31 nuclear magnetic resonance spectrum of the pyridoxal 5'-phosphate cofactor of Escherichia coli -serine dehydratase
(Elsevier, 1989-01)
31P NMR studies were undertaken to determine how potassium ion increases the cofactor affinity of Escherichia coli -serine dehydratase, a model pyridoxal 5'-phosphate requiring enzyme that converts the growth inhibitor ...
Response of human HT-29 colorectal tumor cells to extended exposure to bromodeoxyuridine
(Springer-Verlag, 1989-01)
Effects of the extended exposure of a human colorectal tumor-cell line (HT-29) to bromodeoxyuridine (BrdUrd) were studied in anticipation of the clinical use of that agent to treat colorectal cancer, particularly as a ...
A molecular mechanics (MM2) study of Furan, Thiophene, and related compounds
(John Wiley & Sons, Inc., 1989-07)
The molecular mechanics calculations reported earlier for nitrogen heterocycles have now been extended to include the title compounds, and related molecules. It is in general possible to calculate these structures with an ...
Vibrational analysis of crystalline triglycine
(Elsevier, 1989-12-01)
We have refined vibrational force fields for polypeptides that permit excellent reproduction of the normal mode frequencies of such molecules. This is demonstrated in the present study, in which 80 IR and Raman bands of ...
Viscosity measurements of low temperature molten salts
(Kluwer Academic Publishers; Chapman and Hall Ltd. ; Springer Science+Business Media, 1989-03)
Synthesis of 1,3-diphenyltriazenide complexes of aluminium, gallium and indium: Crystal structure of tris(1,3-diphenyltriazenido)aluminium(III)
(Elsevier, 1989)
The reaction of AlMe3 with 1,3-diphenyltriazene [Hdpt] in toluene gives Al(dpt)3, even when AlMe3 is in large excess. The monomeric structure has been established by X-ray diffraction. Crystals of Al(dpt)3 are monoclinic, ...
Voronoi binding site models: Calculation of binding modes and influence of drug binding data accuracy
(John Wiley & Sons, Inc., 1989-07)
A new and accurate method for calculating the geometrically allowed modes of binding of a ligand molecule to a Voronoi site model is reported. It is shown that the feasibility of the binding of a group of atoms to a Voronoi ...