Now showing items 51-60 of 134
Effector phenotype and immunologic specificity of T cell-mediated adoptive therapy for a murine tumor that lacks intrinsic immunogenicity
(Elsevier, 1990-08)
The MCA 102 sarcoma has been defined by a variety of immunologic studies as a tumor lacking intrinsic immunogenicity. Nevertheless, we have recently demonstrated the feasibility of generating therapeutically effective ...
Distribution of cytochromes P-450, cytochrome b5, and nadph-cytochrome P-450 reductase in an entire human liver
(Elsevier, 1990-02-01)
In rat liver there appear to be significant differences between lobes in the concentration of individual cytochrome P-450 isozymes (Sumner and Lodola, Biochem Pharmacol 36: 391-393, 1987). Because studies in patients often ...
Some determinants of morphology and release rate from poly()lactic acid microspheres
(Elsevier, 1990-07)
Morphology and release rate from poly()lactic acid microspheres were studied as a function of drug loading, drug lipophilicity and solvent evaporation rate. Sudan III was used to exemplify lipophilic compounds, while ...
Mechanism of release from pellets coated with an ethylcellulose-based film
(Elsevier, 1990-12)
Studies were conducted to determine the mechanism of drug release from pellets coated with an ethylcellulose-based pseudolatex widely accepted for use as a sustained release coating for pharmaceuticals. Possible mechanisms ...
Role of O2- in neutrophil recruitment into sites of dermal and pulmonary vasculitis
(Elsevier, 1990)
Using analogous models of acute dermal vasculities and alveolitis in rats, we have examined the role of oxygen-derived metabolities in the tissue damage associated with neutrophil influx into sites of immune complex ...
Heat capacity of deuterated cubic ammonium hexafluorosilicate (ND4)2SiF6 from 6 K to 343 K
(Elsevier, 1990-05)
The heat capacity of deuterated cubic ammonium hexafluorosilicate (ND4)2SiF6 was measured from 6 K to 343 K by adiabatic calorimetry. The curve of heat capacity against temperature is smooth and without anomalies. Values ...
Global systems approach to bacterial physiology: protein responders to stress and starvation
(Elsevier, 1990-12-01)
Two subfamilies of murine retrotransposon ETn sequences
(Elsevier, 1990-02-14)
Early transposon (ETn) elements are 5.7-kb retrotransposons found in the murine genome. We have sequenced large portions of two ETn elements that have apparently transposed within the DNA of a murine myeloma cell line, ...
A comparison of benzodiazepine, serotonin, and dopamine agents in the taste-reactivity paradigm
(Elsevier, 1990-11)
Previous studies have shown that ra'ss positive, palatability-dependent consummatory reactions to infused tastes are selectively facilitated by a benzodiazepine agonist (chlordiazepoxide), and that this effect can be blocked ...