Now showing items 21-26 of 26
DXS165 detects a translocation breakpoint in a woman with choroideremia and a de novo X; 13 translocation
(Elsevier, 1990-04)
The search for the gene for choroideremia (MIM 30310), a rare retinal dystrophy, has been of great interest due to the existence of several choroideremia patients with well-defined structural chromosome aberrations, thus ...
The murine situs inversus viscerum (iv) gene responsible for visceral asymmetry is linked tightly to the Igh-C cluster on chromosome 12
(Elsevier, 1990-07)
The iv gene controls left-right determination during murine organogenesis. To map this gene, we analyzed backcross progeny produced by mating (C57BL/6J x MEV/Ty)F1-iv/+ heterozygotes to C57BL/6J-iv homozygotes. Hybridization ...
Simplified method of making alginate-polylysine microcapsules for hybridoma cell culture using RPMI 1640 medium
(Kluwer Academic Publishers; Science & Technology Letters ; Springer Science+Business Media, 1990-09)
The method of making alginate-poly-L-lysine microcapsules for hybridoma cell culture can be simplified by cultivating the cells in RPMI 1640 medium. Phosphate concentration in RPMI 1640 medium is sufficiently high to ...
Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes
(Elsevier, 1990-11)
Cloned cDNAs representing the entire, homologous (80%) translated sequences of human phosphoribosylpyrophosphate synthetase (PRS) 1 and PRS 2 cDNAs were utilized as probes to localize the corresponding human PRPS1 and PRPS2 ...
Crossovers within a short DNA sequence indicate a long evolutionary history of the APRT*J mutation
(Springer-Verlag, 1990-10)
Adenine phosphoribosyltransferase (APRT) deficiency causing 2,8-dihydroxyadenine urolithiasis and renal failure is present at a high frequency among the Japanese but not other ethnic groups. A special type of mutant allele, ...