Now showing items 41-50 of 136
Evaluation of menogaril in renal cell carcinoma
(Kluwer Academic Publishers; Springer Science+Business Media, 1990-03)
The Southwest Oncology Group (SWOG) studied the response rate and toxicity of menogaril (200 mg/m 2 i.v. q 28 days) in patients with advanced metastatic renal cell carcinoma. During the early stage of the trial two partial ...
An improved method for immobilizing IgG antibodies on protein A-agarose
(Elsevier, 1990-03-09)
This report describes a modification of a procedure developed by others for crosslinking IgG to protein A which itself is covalently linked to a gel support. Earlier immunoaffinity columns were described as having large ...
The effects of morphine on diet selection are dependent upon baseline diet preferences
(Elsevier, 1990-10)
It has been reported that morphine causes a selective increase in the intake of dietary fat. Because we have noted considerable variability among rats in their preferences for carbohydrate and fat, we reasoned that the ...
Telemetric measurement of core temperature in pharmacological research: Validity and reliability
(Elsevier, 1990)
1. The authors present data establishing the reliability and validity of a method for telemetrically measuring core temperature.2. The method is designed to be of particular utility to psychobiological researchers.
Post-meiotic gene expression
(Elsevier, 1990)
Evolutionary arguments and well-designed experiments (based on false premises, however) bad suggested that post-meiotic gene expression did not occur in animals. The technique of molecular genetics have now clearly ...
Comprehensive force field for multiply-chlorinated hydrocarbons
(Elsevier, 1990)
A force field is presented that has been optimized for chlorinated hyrocarbons containing isolated, vicinal, and geminal secondary chlorines. For carbon--chlorine stretch modes, 74 frequencies in 10 molecules are reproduced ...
Modeling drug release from dynamically swelling poly(hydroxyethyl methacrylate-co-methacrylic acid) hydrogels
(Elsevier, 1990-05)
Drug release from a swelling hydrogel matrix is a complicated process where diffusion of drug molecules is coupled to the swelling kinetics. The swelling influences the diffusional flux of drug molecules by increasing the ...
Immobilization can improve the stability of hybridoma antibody productivity in serum-free media
(Wiley Subscription Services, Inc., A Wiley Company, 1990-12-05)
Hybridoma cells (S3H5/Γ2bA2) were cultivated in spinner flasks with 1% serum media and serum-free media. Monoclonal antibody productivity was maintained in 1% serum media. However, cells in serum-free media showed a decrease ...
Feedback regulation and the intracellular protein profile of Streptomyces griseus in a cycloheximide fermentation
(Springer-Verlag, 1990-11)
Two-dimensional gel electrophoresis (2-D PAGE) was used to study the intracellular protein profile of Streptomyces griseus in relation to cycloheximide (CH) biosynthesis. Four proteins (CR1-CR4) were found to be significantly ...