Now showing items 1-10 of 23
The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26
(Elsevier, 1991-10)
Human tissues have two distinct cholinesterase activities: acetylcholinesterase and butyrylcholinesterase. Acetylcholinesterase functions in the transmission of nerve impulses, whereas the physiological function of ...
Tn917 transposase. Sequence correction reveals a single open reading frame corresponding to the tnpA determinant of Tn3-family elements
(Elsevier, 1991-03)
A nucleotide sequence correction on the Enterococcus faecalis transposon Tn917 indicates that what was formerly thought to be two open reading frames (ORF5 and ORF6) is actually one reading frame (ORF5). The latter exhibits ...
Characterization of the human gene for a newly discovered carbonic anhydrase, CA VII, and its localization to chromosome 16
(Elsevier, 1991-12)
Six carbonic anhydrase (CA) isozymes (CA I-VI) in mammals and other amniotes have been described. We have isolated an additional CA gene from a human genomic library and designated its putative product carbonic anhydrase ...
Localization of the panhypopituitary dwarf mutation (df) on mouse chromosome 11 in an intersubspecific backross
(Elsevier, 1991-07)
Ames dwarf (df) is an autosomal recessive mutation characterized by severe dwarfism and infertility. This mutation provides a mouse model for panhypopituitarism. The dwarf phenotype results from failure in the differentiation ...
Determination of the mutations responsible for the lesch-nyhan syndrome in 17 subjects
(Elsevier, 1991-06)
Hypoxanthine -- guanine phosphoribosyltransferase (HPRT) is a purine salvage enzyme that catalyzes the conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. Previous studies of mutant ...
Isolation, characterization, and chromosomal mapping of mouse P450 17[alpha]-hydroxylase/C17-20 lyase
(Elsevier, 1991-05)
Cytochrome P450 17[alpha]-hydroxylase/C17-20 lyase (P45017[alpha]) catalyzes the conversion of C-21 steroids to C-19 steroids in gonads. A full-length mouse cDNA encoding P45017[alpha] was isolated from a mouse Leydig cell ...
African bees in the Americas: Insights from biogeography and genetics
(Elsevier, 1991-01)
The spread of African honey bees in South and Central America is one of the most remarkable and certainly among the most highly publicized instances of biological invasion. Their aggressive nest defense has led to numerous ...
Control of Enterococcus faecalis sex pheromone cAD1 elaboration: Effects of culture aeration and pAD1 plasmid-encoded determinants
(Elsevier, 1991-05)
Aeration of plasmid-free Enterococcus faecalis strains resulted in an 8- to 16-fold decrease in sex pheromone cAD1 activity in culture filtrates. Levels of two unrelated pheromones, cPD1 and cAM373, were unaffected by ...
Duchenne muscular dystrophy
(Elsevier, 1991-06)
Progress in understanding the role of dystrophin raises promising hopes for a treatment for Duchenne muscular dystrophy. In addition, great improvements have been made in the ability to diagnose this disease using simple ...
Plasmids for recombination-based screening
(Elsevier, 1991-09-30)
To facilitate recombination-based screening, we constructed the ColE1-based plasmid, [pi]G4, that confers chloramphenicol resistance, contains a polylinker with multiple unique restriction enzyme recognition sequences, and ...