Now showing items 21-30 of 47
A mouse Y Chromosome pseudogene is related to human ubiquitin activating enzyme E1
(Springer-Verlag, 1992-01)
A 2041 bp DNA fragment isolated from the Sxr (sex reversed) region of the mouse Y Chromosome (Chr) was sequenced and characterized. The sequence, pY8/b, contains four exons that are highly similar to 525 contiguous bases ...
Retrotransposons and the evolution of mammalian gene expression
(Kluwer Academic Publishers; Springer Science+Business Media, 1992-01)
Transposable elements, and retroviral-like elements in particular, are a rich potential source of genetic variation within a host's genome. Many mutations of endogenous genes in phylogenetically diverse organisms are due ...
Metabolic studies in a mouse model of hepatorenal tyrosinemia: Absence of perinatal abnormalities
(Elsevier, 1992-08-31)
SummaryRadiation induced chromosomal deletions at the albino locus in the mouse, lethal when homozygous, cause abnormalities of expression of several unlinked liver specific genes. Recently, the gene encoding FAH was shown ...
Geographic origin of the Y Chromosomes in “old” inbred strains of mice
(Springer-Verlag, 1992-05)
Six distinct Y Chromosomes (Chr) were identified among 39 standard inbred strains of mice with five probes that identified Y Chr-specific restriction fragments on Southern blots. Three Y Chr types, distributed among 31 ...
Targeted delivery of antisense oligonucleotides by molecular conjugates
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1992-11)
Antisense oligonucleotides efficiently inhibit gene expression in vitro; however, the successful therapeutic application of this technology in vivo will require the development of improved delivery systems. In this report ...
Crystallization and preliminary X-ray diffraction studies of the cobalamin-binding domain of methionine synthase from Escherichia coli
(Elsevier, 1992-05-20)
Crystals of a cobalamin-binding domain (Mr = 28,000) have been grown in polyethylene glycol 6000 at pH 7.5, starting from solutions of intact (Mr = 133,000) cobalamin-dependent methionine synthase. The crystals are ...
Quantitation of molecular densities by cryo-electron microscopy : Determination of the radial density distribution of tobacco mosaic virus
(Elsevier, 1992-08-05)
We have determined the absolute mass and radial scattering density distribution of tobacco mosaic virus in the frozen-hydrated state by energy-filtered low-dose bright-field transmission electron microscopy. The absolute ...
Relative nutritional quality of C 3 and C 4 grasses for a graminivorous lepidopteran, Paratrytone melane (Hesperiidae)
(Springer-Verlag, 1992-10)
We tested the hypothesis that C 4 grasses are inferior to C 3 grasses as host plants for herbivorous insects by measuring the relative performance of larvae of a graminivorous lepidopteran, Paratrytone melane (Hesperiidae), ...