Now showing items 51-60 of 149
Intragenic complementation between Escherichia coli trp repressors with different defects in the tryptophan-binding pocket
(Elsevier, 1992-08-01)
Site-directed mutagenesis of the trpR gene (encoding the trp repressor, TrpR) was used to replace Gly85 with tryptophan (Trp or W), in order to place Trp near its normal location in the -tryptophan(-W)-binding pocket. The ...
Detection of oxidative mutagens in an urban air-particulate extract: a preliminary study
(Elsevier, 1992-12)
The Ames assays strains TA98 and TA100 have been useful in characterizing complex mixtures from organic solvent extracts of particles from diesel-powered vehicles, ambient air, and other sources. In this paper we report ...
A convenient, highly stereoselective synthesis of anti-[alpha],[beta]-epoxy alcohols by the Luche reduction of [alpha],[beta]-epoxy ketones
(Elsevier, 1992-10-27)
Reduction of [alpha],[beta]-epoxy ketones under the Luche conditions with NaBH4/CeCl3 in MeOH provides anti- (or erythro-) [alpha],[beta]-epoxy alcohols in high yields and with extremely high stereoselectivity.
Memory T lymphocyte hyporesponsiveness to non-cognate stimuli: a key factor in age-related immunodeficiency
(WILEY-VCH Verlag GmbH, 1992-04)
Previous studies from our laboratory have suggested that aging leads to an accumulation of cells expressing high levels of CD44, thought to be a marker for memory lymphocytes, and that positively selected CD44 hi T cells, ...
Rapid generation of region-specific genomic clones by chromosome microdissection: Isolation of DNA from a region frequently deleted in malignant melanoma
(Elsevier, 1992-11)
Malignant melanoma is frequently characterized by the deletion of the long arm of chromosome 6 (usually encompassing 6q16-q21). In an effort to saturate this region with DNA markers, microdissection and molecular cloning ...
Introduction: A tribute to David L. Nanney, an experimental ciliatologist
(Wiley Subscription Services, Inc., A Wiley Company, 1992)
No Abstract.
Expressed sequence tags and chromosomal localization of cDNA clones from a subtracted retinal pigment epithelium library
(Elsevier, 1992-07)
Expressed sequence tags (ESTs) provide useful molecular landmarks for physical mapping and identify the position of an expressed region in the genome. The use of subtracted cDNA libraries enriched for tissue-specific genes ...
Thermodynamics of ammonium halogenated tellurides II. Heat capacity, phase transitions, and thermodynamic properties of (ND4)2TeCl6 at temperatures from 5 K to 325 K
(Elsevier, 1992-06)
The heat capacity of deuterated ammonium hexachlorotellurate (ND4)2TeCl6 was measured at temperatures T from 5 K to 325 K by adiabatic calorimetry. A small anomaly in the curve of heat capacity against temperature was found ...
Lymphocyte interactions with endothelial cells
(Elsevier, 1992)
Adhesion of lymphocytes to endothelium is vital to lymphocyte migration into lymphoid tissue and into inflammatory sites. In this review, Yoji Shimizu and colleagues identify the molecules that mediate lymphocyte-endothelial ...
Polymorphism in a T-cell receptor variable gene is associated with susceptibility to a juvenile rheumatoid arthritis subset
(Springer-Verlag, 1992-03)
This report demonstrates a T-cell receptor (Tcr) restriction fragment length polymorphism, defined by a Tcrb-V6.1 gene probe and Bgl II restriction enzyme, to be absolutely correlated with allelic variation in the coding ...