Now showing items 71-80 of 158
Euphoriant effects of nicotine in smokers
(Springer-Verlag, 1992-09)
Two studies were conducted to replicate and extend previous demonstrations of smoking-induced, dose-related reports of euphoria, and to confirm this relationship using measures of plasma nicotine. In experiment 1, ...
Isolation and expression of the Drosophila drosulfakinin neural peptide gene product, DSK-I
(Elsevier, 1992-08)
The Drosophila drosulfakinin (dsk) gene encodes the cholecystokinin homologues drosulfakinin-I (DSK-I) and drosulfakinin-II (DSK-II). The naturally occurring DSKI peptide was isolated from an extract of adult flies and its ...
Papaverine effects on PGI2 and TXA2 release from the canine vascular wall
(Elsevier, 1992-07)
Operative manipulation of blood vessels might lead to spasm, thereby destroying the endothelial cell function: the spasm can be prevented by the vasodilator papaverine. To study if this was mediated via the prostanoid ...
Evidence for "stable" organocopper intermediates in the reaction between Me2CuLi[middle dot]LiI and allylic sulfinyl mesylates.
(Elsevier, 1992-08-18)
The addition of Me2CuLi[middle dot]LiI to acyclic allylic sulfinyl mesylates bearing a phenyl functionality in the molecule gives rise to chiral allenes 4 and 11 in variable yields and optical purities, presumably via an ...
Association of the transformed glucocorticoid receptor with a cytoskeletal protein complex
(Elsevier, 1992-03)
In a recent paper we described a system in which glucocorticoid receptors associate with particulate complexes containing tubulin [Cancer Res. 49 (1989) 2222s-2229s]. When L cell cytosol is mixed with a microtubule stabilizing ...
Estimation of the frequency of isoform–genotype discrepancies at the apolipoprotein E locus in heterozygotes for the isoforms
(Wiley Subscription Services, Inc., A Wiley Company, 1992)
Estimates of the impact of apolipoprotein E (apo E) alleles coding for the three common isoforms on plasma lipid levels assume genetic homogeneity among the genotype classes. To test this assumption, we have determined the ...
Creation of immunoglobulin diversity by intrachromosomal gene conversion
(Elsevier, 1992-12)
Not all vertebrates create an immunoglobulin repertoire through the recombination of individual members of variable (V), diversity (D) and joining (J) gene segment families. In chickens, for example, a diverse set of ...
Thermodynamics of ammonium halogenated tellurides I. Heat capacity and thermodynamic properties of (NH4)2 TeCl6 at temperatures from 5 K to 350 K
(Elsevier, 1992-06)
The heat capacity of ammonium hexachlorotellurate (NH4)2TeCl6 was measured at temperatures from 5 K to 350 K. The heat-capacity curve shows a small anomaly around 86 K and a broad peak extending from 100 K to 280 K. The ...
Preparation and reactions of 1,1-zinc, boron and 1,1-copper, boron alkenyl bimetallics
(Elsevier, 1992-06-23)
Pinacol [alpha]-iodoalkenylboronates 8, readily prepared by the hydroboration of 1-iodoalkynes, were converted to 1,1-bimetallics of boron and zinc or copper which react with a wide range of electrophiles affording ...
Lipophilicity of opioids determined by a novel micromethod
(Elsevier, 1992-04)
The lipophilicity of various [mu]-selective opioids was determined by measuring their distribution between n-octanol and Tris.HCl buffer, pH 7.4, by a procedure requiring submicromolar concentrations (submilligram amounts) ...