Now showing items 61-70 of 116
Determination of plasma propofol levels using gas chromatography--mass spectrometry with selected-ion monitoring
(Elsevier, 1993-10-29)
Propofol (2,6-diisopropylphenol, I.C.I. 35 868) is a rapid-acting, intravenous anesthetic agent recently introduced for the induction and maintenance of general anesthesia. This paper describes a gas chromatographic--mass ...
Potentiometric ion- and bioselective electrodes based on asymmetric polyurethane membranes
(Elsevier, 1993-03-01)
The potentiometric ion responses of ammonium- and proton-selective electrodes prepared by incorporating appropriate neutral carriers within novel asymmetric polyurethane membranes are reported. The membranes are formed by ...
Baculovirus-Mediated Expression of Rat Liver CTP:Phosphocholine Cytidylyltransferase
(Elsevier, 1993-02)
We describe herein the expression and purification of milligram quantities of rat liver CTP:phosphocholine cytidylyltransferase in recombinant baculovirus-infected insect cells. The enzyme was purified by incorporating ...
The preparation and morphology of PPO–epoxy blends
(Wiley Subscription Services, Inc., A Wiley Company, 1993-05-10)
Poly(phenylene oxide) (PPO) was found to be miscible in diglycidyl ether of bisphenol A (DGEBA) based epoxy. The PPO–DGEBA system exhibited upper critical solution temperature (UCST) behavior. The cloud point temperatures ...
Energetics of the disulfide bridge: An ab initio study
(Wiley Subscription Services, Inc., A Wiley Company, 1993-10)
The energetics of the Χ 1 2 Χ 3 Χ 2 2 portion of the disulfide bridge have been obtained from an ab initio study of diethyl disulfide. Calculations at the 3-21G* level were done on relaxed structures at every ∼ 30° ...
Why are binding-site models more complicated than molecules?
(Kluwer Academic Publishers; ESCOM Science Publishers B.V. ; Springer Science+Business Media, 1993-12)
A commonly occurring problem in drug development is that the binding affinities for a few compounds to a particular binding site on some protein have been measured, but the crystal structure for that protein is not available. ...
2-Chlorophenol oxidation in supercritical water: Global kinetics and reaction products
(American Institute of Chemical EngineersWiley Periodiocals, Inc., 1993-01)
2-Chlorophenol (2CP) was oxidized in near-critical and supercritical water in a high-pressure plug-flow reactor. The global kinetics for 2CP disappearance were described by a rate law that was 0.88±0.06 order in 2CP, ...
Synthesis of state feedback laws for end-point optimization in batch processes
(Elsevier, 1993-01)
This work studies the class of singular optimal control problems, where a performance index must be optimized at the final time of operation of a batch process. Optimal state feedback laws for the singular region of operation ...
Model studies of lantibiotic biogenesis
(Elsevier, 1993-12-03)
A six residue polypeptide has been synthesized to study the proposed biosynthesis of lanthionine. It is shown that this peptide spontaneously cyclizes in a biomimetic fashion via a completely stereoselective intramolecular ...
The role of data in the EIS process: Evidence from the BLM wilderness review
(Elsevier, 1993-03)
Various propositions have been offered about the role of the environmental impact statement (EIS) in agency decision making. These include statements that agencies are (1) using the information collected in the EIS to make ...