Now showing items 31-40 of 53
Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms : Cleavage at a single arginine residue
(Elsevier, 1994-01-03)
Processing of rat prodynorphin (proDyn) by the mouse prohormone convertase PCI was investigated. Recombinant vaccinia virus vectors were used to coexpress proDyn and PC1 in rat PC12 pheochromocytoma and mouse AtT-20 ...
Molecular Cloning and Structural Analysis of the Rabbit Gastrin/CCKB Receptor Gene
(Elsevier, 1994-07-29)
Gastrin and cholecystokinin exert a variety of physiological actions in the central nervous system and digestive tract that are mediated through one or more receptors exhibiting similar affinity for the two peptides. We ...
Genotype-specific effects of elevated CO 2 on fecundity in wild radish ( Raphanus raphanistrum )
(Springer-Verlag, 1994-02)
Rising atmospheric CO 2 may lead to natural selection for genotypes that exhibit greater fitness under these conditions. The potential for such evolutionary change will depend on the extent of within-population genetic ...
Localization of the peptidylglycine α-amidating monooxygenase gene ( Pam ) introduces a region of homology between human Chromosome 5q and mouse Chromosome 1
(Springer-Verlag; Springer-Verlag New York Inc, 1994-11)
Structure-Function Analysis of CYP2A10 and CYP2A11, P450 Cytochromes That Differ in Only Eight Amino Acids But Have Strikingly Different Activities toward Testosterone and Coumarin
(Elsevier, 1994-08-30)
Cytochrome P450 NMa, which was first identified in this laboratory in rabbit nasal microsomes, is now known to represent two distinct gene products, P450s 2A10 and 2A11. In the present study; chimeric and site-directed ...
Chromosomal localization of the transcription factor YY1 in the mouse and human
(Springer-Verlag, 1994-04)
Spontaneous Calcium Oscillations in Clonal Endocrine Pancreatic Glucagon-Secreting Cells
(Elsevier, 1994-11-30)
Measurements of the cytosolic calcium concentration in single cells of the clonal endocrine pancreatic glucagon-secreting cell line INR1 G9 revealed the existence of spontaneous calcium oscillations in 20 - 70 % of these ...
A Newly Cloned Phospholipase A2-Activating Protein Elicits Ca2+ Oscillations and Pancreatic Amylase Secretion via Mediation of G Protein [beta]/Phospholipase A2/Arachidonic Acid Cascades
(Elsevier, 1994-09-30)
Recently we have demonstrated that in rat pancreatic acini the high affinity cholecystokinin receptors are coupled to the phospholipase A2 (PLA2)/arachidonic acid (AA) cascades to mediate Ca2+ oscillations and amylase ...
Maturity-onset diabetes of the young
(Elsevier, 1994)
Maturity-onset diabetes of the young (MODY) is a subtype of noninsulin dependent diabetes mellitus (NIDDM). It is characterized by an early age of onset and autosomal dominant mode of inheritance. These features and the ...
Binding and cAMP Studies of Melanotropin Peptides with the Cloned Human Peripheral Melanocortin Receptor, hMC1R
(Elsevier, 1994-11-14)
Binding and stimulation of cAMP by the melanotropin peptides [alpha]-MSH ([alpha]-melanocyte-stimulating hormone) and its superpotent analogues [Nle4, Phe7] [alpha]-MSH (MT-I) and [formula] [alpha]-MSH4-10-NH2 (MT-II) were ...