Now showing items 71-80 of 179
Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes
(Elsevier, 1994-10)
T-cell activation in the absence of co-stimulatory signals can lead to induction of anergy. Professional antigen-presenting cells (APCs) of bone marrow origin, such as macrophages and dendritic cells, can provide co-stimulation ...
Predictors of toxicity in treating patients with neuroblastoma by radiolabeled metaiodobenzylguanidine
(Springer-Verlag, 1994-01)
We searched for methods that would enable prescriptions of the maximum tolerable doses of iodine-131 metaiodobenzylguanidine (MIBG) and iodine-125 MIBG in the treatment of patients with neuroblastoma. We correlated doses, ...
Enhanced diagnostic efficiency of the polymerase chain reaction by co-amplification of multiple regions of HIV-1 and HIV-2
(Elsevier, 1994-08)
A method for co-amplification of multiple viral sequences of HIV-1 and HIV-2 by polymerase chain reaction was designed. The technique resulted in the specific detection of each type of virus and allowed the amplification ...
Bacteriophage T4 ribonucleoside diphosphate reductase: on the defect causing decreased formation of the [beta]293 subunit encoded by the nrdB93 mutant gene
(Elsevier, 1994-05-03)
Bacteriophage T4 ribonucleoside diphosphate reductase is composed of two proteins, [alpha]2 and [beta]2, encoded by the nrdA and nrdB genes, respectively. The expression of nrdB is the limiting factor for the assembly of ...
Costimulation of Superantigen-Activated T Lymphocytes by Autologous Dendritic Cells Is Dependent on B7
(Elsevier, 1994-06)
Highly purified populations of dendritic cells (DCs) can be isolated from various tissues such as skin and blood. These sites are likely to encounter secreted toxins of bacteria such as super-antigens. In vivo, DCs express ...
A system for gene cloning and manipulation in the yeast Candida glabrata
(Elsevier, 1994-05-03)
The opportunistic pathogenic yeast, Candida (Torulopsis) glabrata, is an asexual imperfect fungus that exists largely as a haploid. Besides being a clinically important pathogen, this yeast also provides a model system for ...
Extensive sequence divergence in the 3' inverted repeat of the chloroplast rbcL gene in non-flowering land plants and algae
(Elsevier, 1994-09-02)
A stem-loop region is present at the 3' terminus of the chloroplast rbcL mRNA in all taxa surveyed to date. In spinach, this structure has been shown by others to be involved in modulating transcript stability and correct ...