Now showing items 21-30 of 181
Modulation of opioid signal transduction in SH-SY5Y neural cells by differentiating agents: Concurrent mu receptor upregulation and effector desensitization by phorbol ester
(Elsevier, 1994-02-21)
Long-term exposure of SH-SY5Y human neural cells to retinoic acid (RA) increased the binding of [3H]DAMGO and [3H]DPDPE by up to 3-fold compared to membranes of untreated cells. In contrast, incubation of the cells with ...
The interaction of artemisinin with malarial hemozoin
(Elsevier, 1994-01)
[14C]Artemisinin was taken up by Plasmodium falciparum in culture and concentrated in hemozoin. In vitro, hemin and artemisinin were found to undergo a chemical reaction forming two major products which were isolated by ...
Expression of Wild-Type and Mutant Rat Liver CTP: Phosphocholine Cytidylyltransferase in a Cytidylyltransferase-Deficient Chinese Hamster Ovary Cell Line
(Elsevier, 1994-05)
The strain 58 Chinese hamster ovary (CHO) mutant defective in CTP:phosphocholine cytidylyltransferase was characterized as an expression system for exogenous cytidylyltransferase. Strain 58 cells express less than 5% of ...
Synthesis and assignments of regioisomeric cyanoimidazole esters
(Elsevier, 1994-02-28)
Regioassignments of ethyl cyanoimidazolecarboxylates have been performed by the nuclear Overhauser effect(NOE) studies on the regioisomeric monocyanoimidazoles obtained by the hydrolysis of the esters followed by ...
Synthesis of (+/-)tylophorine by the intramolecular cycloaddition of an azide with an [omega]-chloroalkene
(Elsevier, 1994)
Cyclization of (Z)-1-(2-chloromethyl)phenyl-5-azidopent-1-ene 10 in benzene at 120[deg]C followed by treatment with sodium borohydride produced 1,2,3,5,10,10a-hexahydropyrrolo[1,2-b]isoquinoline 11 in 71% yield. A similar ...
Thermodynamics of alkali alkanoates X. Heat capacities and thermodynamic properties of lithium methanoate and lithium ethanoate at temperatures from [approximate] 5 K to 580 K
(Elsevier, 1994-12)
Heat capacities of lithium methanoate and ethanoate (CA Registry numbers [556-63-8] and [546-89-4]) have been measured by adiabatic intermittent-heating equilibrium calorimetry from temperatures T near 5 K to 350 K and by ...
Hydrazine adsorption and decomposition on the GaAs(100)-c(8 x 2) surface
(Elsevier, 1994-12-20)
Temperature programmed desorption (TPD), X-ray photoelectron spectroscopy (XPS), and high resolution electron energy loss spectroscopy (HREELS) have been used to study the decomposition mechanism of hydrazine (N2H4) on the ...
Yeast expression vectors using RNA polymerase III promoters
(Elsevier, 1994-12-30)
A series of Saccharomyces cerevisiae -- Escherichia coli shuttle vectors is described in which small RNAs can be stably expressed in yeast from two different promoters for RNA polymerase III transcription. The vectors are ...
Slouching toward a systems approach to treatment
(Elsevier, 1994)
Both the health care sector generally and the alcohol and drug field are moving toward a truly systematic approach to treatment, accelerated by the anticipated advent of health care reform. There is considerable reluctance ...
An evaluation of the rotational barrier about the B---N bond of 1-aminoborepins
(Elsevier, 1994-04-05)
13C NMR spectroscopy has been used to determined the barriers to rotation about the B---N bonds of 1-(N-benzyl-N-methylamino)borepin and 1-(N-benzyl-N-methylamino)-4,5-dihydroborepin as 18 and 19.8 kcal mol-1, respectively. ...