Now showing items 11-20 of 31
Current benzodiazepine issues
(Springer-Verlag, 1995-03)
This article deals with some of the recent evidence bearing on the issues of the liability of benzodiazepines to lead to abuse, dependence, and adverse behavioral effects. Reviews of epidemiological, clinical and experimental ...
Psychiatric comorbidity of smoking and nicotine dependence
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1995-03)
Recent epidemiologic studies have revealed that comorbidity of psychiatric disorders is far more pervasive than previously suspected. Strong associations have been reported between specific substance use disorders and ...
Countercurrent gradient chromatography: A continuous focusing technique
(Wiley Subscription Services, Inc., A Wiley Company, 1995-12-05)
The continuous separation of proteins was performed in a countercurrent gradient chromatography (CGC) system. A magnetically stabilized fluidized bed (MSFB) was used to establish true countercurrent contact of a solid resin ...
Subcellular distribution of terminal α-D- and β-D-galactosyl residues in Ehrlich tumour cells studied by lectin-gold techniques
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1995-04)
We have studied by high resolution in situ light and electron microscopic lectin-gold techniques the subcellular distribution of α- d -Gal residues using the Griffonia simplicifolia I-B 4 isolectin and compared it with ...
The development of sensitization to the psychomotor stimulant effects of amphetamine is enhanced in a novel environment
(Springer-Verlag, 1995-02)
Two experiments were designed to assess the effect of a “novel” environment on the development of sensitization to the psychomotor activating effects of d -amphetamine. In the first experiment, rats with a unilateral ...
Long-term effects of brief antihypertensive treatment on systolic blood pressure and vascular reactivity in young genetically hypertensive rats
(Kluwer Academic Publishers; Springer Science+Business Media, 1995-06)
Recent studies have shown that angiotensin converting enzyme (ACE) inhibitor treatment in young spontaneously hypertensive rats (SHR) reduces blood pressure into adulthood. This study explored changes in vascular reactivity ...
Role of calcium channel blocking agents in the prevention of atherosclerosis
(Kluwer Academic Publishers; Springer Science+Business Media, 1995-01)
Calcium channel blocking agents, although effective and widely used in the symptomatic therapy of hypertension and ischemic heart disease, have an uncertain effect on the development of coronary atherosclerosis, plaque ...
FDG PET imaging of paragangliomas of the neck: comparison with MIBG SPET
(Springer-Verlag, 1995-11)
Two patients with cervical paragangliomas underwent positron emission tomography (PET) with 2-[ 18 F]-fluoro-2-deoxy-D-glucose (FDG). There was marked tumor uptake and retention of FDG. Adjacent salivary gland accumulation ...
Monte Carlo simulations of membrane signal transduction events: Effect of receptor blockers on G-protein activation
(Kluwer Academic Publishers; Biomedical Engineering Society ; Springer Science+Business Media, 1995-05)
Cells have evolved elaborate strategies for sensing, responding to, and interacting with their environment. In many systems, interaction of cell surface receptors with extracellular ligand can activate cellular signal ...
Detection of genome similarity as an exploratory tool for mapping complex traits
(Wiley Subscription Services, Inc., A Wiley Company, 1995)
For one- and two-trait-locus models, we show that the lod score based on affected relative pairs or trios is a monotonically increasing function of the genome similarity measured by the proportion of alleles shared identical ...