Now showing items 21-30 of 31
Evaluation of merbarone (NSC 336628) in disseminated malignant melanoma
(Kluwer Academic Publishers; Springer Science+Business Media, 1995-06)
Merbarone, NSC 336628, is an investigational anticancer drug with activity against experimental animal tumors including melanoma. This paper presents results of a Phase II clinical study of merbarone in patients with biopsy ...
Recombination fraction estimate of zero in the presence of apparent recombinants: Effects of incomplete penetrance and sporadic cases
(Wiley Subscription Services, Inc., A Wiley Company, 1995)
For a fully penetrant trait, apparent recombinants between the trait and marker loci result in an estimate of the recombination fraction θ > 0. Given allowance for reduced penetrance and/or sporadic cases, this no longer ...
Two highly polymorphic CA repeats in the Menkes gene (ATP7A)
(Springer-Verlag, 1995-09)
Two highly polymorphic CA repeats have been identified in the Menkes gene ( ATP7A ). These repeats should be useful for prenatal diagnosis and carrier detection in families with Menkes disease and X-linked cutis laxa. The ...
Variation at the M235T locus of the angiotensinogen gene and essential hypertension: a population-based case-control study from Rochester, Minnesota
(Springer-Verlag, 1995-09)
A variant of the angiotensinogen gene, M235T, has been associated with essential hypertension in selected subjects from Paris, France and Salt Lake City, Utah. In the present report, we studied a population-based sample ...
Modulation of adhesive properties of DEAE-dextran with laminin
(John Wiley & Sons, Inc., 1995-08)
Human squamous epithelial cells produce lower amounts of laminin and fibronectin when cultured on DEAE-dextran than when cultured on gelatin-coated polystyrene ( Biotechnol. Bioeng. , 33:1235). The epithelial cells also ...
Rebuttal of comments by Griffiths, Lader and Greenblatt to Review by Woods and Winger
(Springer-Verlag, 1995-03)
Aniline hydrogenolysis on nickel: effects of surface hydrogen and surface structure
(Baltzer Science Publishers, Baarn/Kluwer Academic Publishers; J.C. Baltzer AG, Science Publishers ; Springer Science+Business Media, 1995-09)
Fluorescence yield near-edge spectroscopy (FYNES) above the carbon K edge and temperature programmed reaction spectroscopy (TPRS) have been used as the methods for characterizing the reactivity and structure of adsorbed ...
An intragenic Taq I polymorphism in the faciogenital dysplasia (FGD1) locus, the gene responsible for Aarskog syndrome
(Springer-Verlag, 1995-10)
A Taq I polymorphism, located in intron 4 of the faciogenital dysplasia ( FGD1 ) gene, the gene responsible for Aarskog syndrome, is described. FGD1 encodes a putative Rho/Rac guanine nucleotide exchange factor involved ...
Tumor-specific granulocyte/macrophage colony-stimulating factor and interferon γ secretion is associated with in vivo therapeutic efficacy of activated tumor-draining lymph node cells
(Springer-Verlag, 1995-09)
In this study, cytokine release by tumor-draining lymph node cells sensitized in vitro (IVS-TDLN) was examined and correlated with therapeutic efficacy in adoptive immunotherapy. Mice bearing immunologically distinct MCA ...