Now showing items 21-30 of 35
FDG PET imaging of paragangliomas of the neck: comparison with MIBG SPET
(Springer-Verlag, 1995-11)
Two patients with cervical paragangliomas underwent positron emission tomography (PET) with 2-[ 18 F]-fluoro-2-deoxy-D-glucose (FDG). There was marked tumor uptake and retention of FDG. Adjacent salivary gland accumulation ...
Monte Carlo simulations of membrane signal transduction events: Effect of receptor blockers on G-protein activation
(Kluwer Academic Publishers; Biomedical Engineering Society ; Springer Science+Business Media, 1995-05)
Cells have evolved elaborate strategies for sensing, responding to, and interacting with their environment. In many systems, interaction of cell surface receptors with extracellular ligand can activate cellular signal ...
Detection of genome similarity as an exploratory tool for mapping complex traits
(Wiley Subscription Services, Inc., A Wiley Company, 1995)
For one- and two-trait-locus models, we show that the lod score based on affected relative pairs or trios is a monotonically increasing function of the genome similarity measured by the proportion of alleles shared identical ...
Evaluation of merbarone (NSC 336628) in disseminated malignant melanoma
(Kluwer Academic Publishers; Springer Science+Business Media, 1995-06)
Merbarone, NSC 336628, is an investigational anticancer drug with activity against experimental animal tumors including melanoma. This paper presents results of a Phase II clinical study of merbarone in patients with biopsy ...
Recombination fraction estimate of zero in the presence of apparent recombinants: Effects of incomplete penetrance and sporadic cases
(Wiley Subscription Services, Inc., A Wiley Company, 1995)
For a fully penetrant trait, apparent recombinants between the trait and marker loci result in an estimate of the recombination fraction θ > 0. Given allowance for reduced penetrance and/or sporadic cases, this no longer ...
Two highly polymorphic CA repeats in the Menkes gene (ATP7A)
(Springer-Verlag, 1995-09)
Two highly polymorphic CA repeats have been identified in the Menkes gene ( ATP7A ). These repeats should be useful for prenatal diagnosis and carrier detection in families with Menkes disease and X-linked cutis laxa. The ...
Variation at the M235T locus of the angiotensinogen gene and essential hypertension: a population-based case-control study from Rochester, Minnesota
(Springer-Verlag, 1995-09)
A variant of the angiotensinogen gene, M235T, has been associated with essential hypertension in selected subjects from Paris, France and Salt Lake City, Utah. In the present report, we studied a population-based sample ...
Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin‐1: a potential mechanism for inflammatory angiogenesis
(Wiley Periodicals, Inc.W.B. Saunders Co, 1995-09-18)
Modulation of adhesive properties of DEAE-dextran with laminin
(John Wiley & Sons, Inc., 1995-08)
Human squamous epithelial cells produce lower amounts of laminin and fibronectin when cultured on DEAE-dextran than when cultured on gelatin-coated polystyrene ( Biotechnol. Bioeng. , 33:1235). The epithelial cells also ...