Now showing items 21-30 of 32
NMRD studies on phthalate dioxygenase: evidence for displacement of water on binding substrate
(Springer-Verlag; Society of Biological Inorganic Chemistry, 1996-10)
Water proton T 1 –1 measurements at magnetic fields between 0.01 and 50 MHz [nuclear magnetic relaxation dispersion (NMRD) measurements] have been performed on solutions of phthalate dioxygenase (PDO) reconstituted at the ...
Studies of the action of ceramide-like substances ( d - and l -PDMP) on sphingolipid glycosyltransferases and purified lactosylceramide synthase
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-06)
We have studied the effects of D -threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol ( D -PDMP) and its L -enantiomer on glycosphingolipids in cultured normal human kidney proximal tubular cells. We found that D -PDMP ...
Clocinnamox antagonism of opioid suppression of schedule-controlled responding in rhesus monkeys
(Springer-Verlag, 1996-02)
The antagonist effects of clocinnamox were evaluated against opioid agonists, acting at μ, κ and ∂-receptors, in rhesus monkeys ( n =3–4) responding under a fixed-ratio 30 (FR 30) schedule for food delivery. Clocinnamox ...
First-principles study of the α-Al 2 O 3 (0001)/Cu(111) interface
(Kluwer Academic Publishers; Springer Science+Business Media, 1996-12)
Adhesive energetics and interfacial electronic structures have been computed from first principles for the Cu/Al 2 O 3 interface. Recent transmission electron microscopy results of Cu grown by molecular beam epitaxy on Al ...
Association between common alleles of the low-density lipoprotein receptor gene region and interindividual variation in plasma lipid and apolipoprotein levels in a population-based sample from Rochester, Minnesota
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1996-12)
This paper presents an analysis of the relationship between variation in the low-density lipoprotein receptor (LDLR) gene region and interindividual variation in plasma lipid and apolipoprotein levels in a sample representative ...
Direct transfer of a foreign MHC gene into human melanoma alters T cell receptor Vβ usage by tumor-infiltrating lymphocytes
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1996-10)
The direct introduction of foreign genes into tumors shows promise as a therapeutic modality to enhance tumor immunogenicity. Hence, melanoma nodules were directly injected with a vector encoding an allogeneic MHC class ...
Diverse manifestations of tumorigenicity and immunogenicity displayed by the poorly immunogenic B16-BL6 melanoma transduced with cytokine genes
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1996-06)
We evaluated the in vivo response to the poorly immunogenic B16-BL6 (BL6) murine melanoma genetically altered to secrete interleukin-2 (IL-2), IL-4, interferon γ (IFNγ) and granulocyte/macrophage-colony-stimulating factor ...
Cell growth and differentiation on feeder layers is predicted to be influenced by bioreactor geometry
(Wiley Subscription Services, Inc., A Wiley Company, 1996-06-05)
Tissue function is comprised of a complex interplay between biological and physicochemical rate processes. The design of bioreactors for tissue engineering must account for these processes simultaneously in order to obtain ...
Preparation and characterization of high-surface-area polymer substrates for microcalorimetry
(John Wiley & Sons, Inc., 1996-05)
The preparation and characterization of high-surface-area polymeric substrates suitable for the microcalorimetry of protein adsorption are described. High-surface-area polystyrene, poly(styrene- co -butyl methacrylate) and ...
Genotypes with the apolipoprotein ε4 allele are predictors of coronary heart disease mortality in a longitudinal study of elderly Finnish men
(Springer-Verlag, 1996-05)
Earlier we reported that allelic variation in the gene coding for apolipoprotein (apoE) is a significant predictor of variation in the risk of coronary heart disease (CHD) death in a longitudinal study of elderly Finnish ...