Now showing items 31-40 of 40
Molecular Modeling of Nucleic Acid Structure: Setup and Analysis
(Wiley Periodicals, Inc.Oxford University Press, 2001-09)
The last in a set of units by these authors, this unit addresses some important remaining questions about molecular modeling of nucleic acids. It describes how to choose an appropriate molecular mechanics force field; how ...
Molecular Modeling of Nucleic Acid Structure: Electrostatics and Solvation
(Wiley Periodicals, Inc.Oxford University Press, 2001-07)
This unit presents an overview of computer simulation techniques as applied to nucleic acid systems, ranging from simple in vacuo molecular modeling techniques to more complete all‐atom molecular dynamics treatments that ...
Use of Electrophilic Substitution to Form Site‐Specific Cross‐Links in DNA
(Wiley Periodicals, Inc., 2001-09)
This unit describes the synthesis, purification, and analysis of modified oligodeoxynucleotides containing 4‐thio‐2′‐deoxyuridine, and the use of these modified oligodeoxynucleotides in conjunction with bis‐electrophilic ...
Molecular Modeling of Nucleic Acid Structure: Energy and Sampling
(Wiley Periodicals, Inc.Oxford University Press, 2001-04)
An overview of computer simulation techniques as applied to nucleic acid systems is presented. This unit expands an accompanying overview unit (UNIT ) by discussing methods used to treat the energy and sample representative ...
A polarizable electrostatic model of the N-methylacetamide dimer
(John Wiley & Sons, Inc., 2001-12)
Our previously developed polarizable electrostatic model is applied to isolated N-methylacetamide (NMA) and to three hydrogen-bonded configurations of the NMA dimer. Two versions of the model are studied. In the first one ...
Incorporation of Halogenoalkyl, 2‐Pyridyldithioalkyl, or Isothiocyanate Linkers into Ligands
(IRL PressWiley Periodicals, Inc., 2001-07)
Ligands can be introduced at the 5’ terminus of an oligonucleotide by adding a linker to the ligand and modifying the 5’ terminus of the oligonucleotide. These are then reacted to give the ligand‐oligonucleotide conjugate. ...
Existence of a critical carbon number in the aging of a wax-oil gel
(Wiley Subscription Services, Inc., A Wiley Company, 2001-09)
A fundamental study was carried out to understand the aging (or hardening) of the wax-oil gels formed in the subsea pipelines during the flow of crude oil from offshore wells to shore. The aging process is a counterdiffusion ...
Commentary: Landmark articles on copper in the field of human health
(John Wiley & Sons, Inc., 2001)
No abstract.
Fracture behavior of glass bead filled epoxies: Cleaning process of glass beads
(John Wiley & Sons, Inc., 2001-02-22)
Inorganic particles are commonly cleaned with solvents such as alcohols before being incorporated into thermoset polymers as fillers or tougheners, but the role of the cleaning process has never been examined. In this ...
Analysis of Oxidized DNA Fragments by Gel Electrophoresis
(Wiley Periodicals, Inc., 2001-04)
Polyacrylamide gel electrophoresis is used to define and quantify products of deoxyribose oxidation in DNA, based on the unique electrophoretic mobility of DNA fragments possessing deoxyribose oxidation products on their ...