Now showing items 921-930 of 959
The Transition of Chief Nurse Executives into Chief Executive Officer and Chief Operating Officer Roles.
(2009)
It is difficult navigating the whitewaters of today’s healthcare. Finding and keeping a competent and capable chief executive officer (CEO) and chief operating officer (COO) is pivotal to successful navigation. Chief ...
Ameloblastin: Evolution, Structure and Function in Enamel Formation.
(2009)
Dental enamel formation is dependent upon the secretion of three enamel proteins: amelogenin, enamelin, and ameloblastin (Ambn). These proteins contribute to a mineralization front on the secretory surface of ameloblasts. ...
The Function of the Monomeric Form of the Mu-Opioid Receptor: G Protein- Mediated Allosteric Regulation of Agonist Binding and Stimulation of Nucleotide Exchange. Nucleotide Exchange.
(2009)
Opioids have been the mainstays to alleviate pain for millennia. The opioid receptors responsible for analgesia are G protein-coupled receptors (GPCRs) which bind several endogenous ligands and couple to multiple isoforms ...
Oxidation of the Endogenous Cannabinoid Arachidonoyl Ethanolamide (Anandamide) by Cytochrome P450 Enzymes
(2009)
Arachidonoyl ethanolamide (anandamide), an endogenous derivative of arachidonic acid, activates the same molecular targets as the main psychoactive constituent of the cannabis (marijuana) plant and it is therefore classified ...
Metabolic Syndrome and Workplace Outcomes.
(2009)
Metabolic syndrome is a cluster of five risk factors which have been shown to be associated with increased odds of developing certain medical conditions such as heart disease and diabetes. However, changing definitions ...
Pulmonary Innate Immune Modulation in the Pathogenesis of Allergic Asthma.
(2009)
Recent studies have shown that the innate immune response plays a significant role in the adaptive immune response in asthma. However, controversy exists regarding whether innate immune activating substances such as ...
Regulation of Cytokines and Chemokines during the Progression of Acute Inflammation in the Human Whole Blood Model.
(2009)
Traumatic injuries or infectious challenges activate the innate immune response, initiating inflammation and cytokines and chemokines that are released into circulation in distinct kinetic patterns. In the clinic, patients ...
Novel Bioinformatics Approaches for MicroRNA Detection and Target Prediction.
(2009)
MicroRNAs (miRNAs) are regulators of gene expression at the post-transcriptional level. Scientists have not been able to fully unlock their therapeutic potential because their functions and mechanisms of action have not ...
Inhalability and Personal Sampler Performance for Aerosols at Ultra-Low Windspeeds.
(2009)
Inhalability is the efficiency with which people inhale airborne particles through the nose or mouth during breathing. Most previous studies used to set criteria for this were based on high-speed wind tunnels, using breathing ...
Perceptions of Risk for the Development of Type 2 Diabetes in African-American Women with Gestational Diabetes.
(2009)
Introduction: African-American mothers with a history of gestational diabetes are at a significant risk for the development of subsequent type 2 diabetes. The purpose of this investigation was to study African-American ...