Now showing items 931-940 of 959
The Impact of Molecular Complexation on Intestinal Membrane Permeation.
(2009)
This dissertation focuses on the impact of molecular complexation on intestinal membrane permeation. Two cases in which molecular complexation in solution affects intestinal membrane transport are considered: 1) enhancement ...
Social and Biological Predictors of Blood Pressure in Hypertensives.
(2009)
Hypertension affects 1 in 4 adults in the United States and is a major contributor to cardiovascular morbidity and mortality. Blood pressure (BP) control is observed in slightly less than two-thirds of those on antihypertensive ...
Interleukin-6 TGFb Promote Connective Tissue Growth Factor in Chronic Cardiac Allograft Rejection.
(2009)
Cardiac transplantation is an effective treatment for multiple types of heart failure refractive to therapy. Although immunosuppressive therapeutics have increased survival rates within the first year post-transplant, ...
Mechanisms Involved in the Psychological Distress of Black Caribbeans in the United States.
(2009)
The accelerated growth of ethnic minorities implores academics to investigate more deeply health disparities and the factors that exacerbate or minimize such inequalities. This dissertation attends to that concern by using ...
Social Stigma and HIV/AIDS in Black MSM.
(2009)
In this multi-method, interdisciplinary dissertation I contribute to the growing literature on HIV/AIDS in Black men who have sex with men (MSM) through accomplishing the following. In my first dissertation paper, I use ...
Raman Spectroscopy Detection of Molecular Changes Associated with Osteoarthritis.
(2009)
Vibrational spectroscopic methods are minimally invasive, and are appropriate for use in clinical contexts. Methods were developed in this dissertation for evaluating joint damage and disease using Raman spectroscopy. ...
Crosstalk between Endothelial Cells and Tumor Cells in Head and Neck Cancer
(2009)
Tumor angiogenesis is necessary for cancer progression and requires active interaction between endothelial cells and tumor cells. It is well established that cancer cells secrete angiogenic factors to recruit and sustain ...
Dynamic Regulation of Vacuole Homeostasis during Infection by Intracellular Dynamic Regulation of Vacuole Homeostasis during Infection by Intracellular Bacterial Pathogens.
(2009)
Pathogen-containing vacuoles (PCV) are a rich interface for interaction of intracellular pathogens and their mammalian host cells. This thesis investigates mechanisms by which host and pathogen regulate the vacuolar ...
On the Intersection of Race, Stress, and Health.
(2009)
The challenge of eliminating racial and ethnic health disparities has been a daunting task. These disparities are highly multi-factorial in nature, and researchers have been unable to elucidate the exact mechanisms, and ...
High-Throughput Screening for Small-Molecule Inhibitors of the Ga12/13/RhoA Signaling Pathway.
(2009)
Cancer metastasis is a major health problem that involves movement of tumor cells from their primary tissue site to a secondary tissue site. Cellular functions involved in metastasis include cell proliferation, adhesion, ...