Now showing items 941-950 of 959
Effects of Physical Guidance on Motor Control and Learning During Human Walking.
(2009)
Physical guidance is often used in rehabilitation when teaching patients to re-learn movements. However, the effects of guidance on motor learning of complex skills are not clear. The overall goal of this dissertation is ...
SH2B1 Regulates Insulin Sensitivity and Glucose Homeostasis by Multiple Mechanisms.
(2009)
Leptin and insulin are key hormonal regulators of energy balance and glucose homeostasis. SH2B1 is a PH- and SH2-domain containing adapter protein that promotes both leptin and insulin signaling in cells. Disruption of ...
SMARTS Approach to Chemical Data Mining and Physicochemical Property Prediction.
(2009)
The calculation of physicochemical and biological properties is essential in order to facilitate modern drug discovery. Chemical spaces dimensionalized by these descriptors have been used to scaffold-hop in order to discover ...
Adolescent Coping and Family Functioning in the Family of a Child with Autism
(2009)
Autism is on the rise at an alarming rate. Autism impacts all members of a family
including siblings. There is much research that examines the etiology of autism but there
is little research that explores, from the sibling ...
Measures of Emotion: How Feelings are Expressed in the Body and Face During Walking.
(2009)
The goal of this dissertation was to assess multimodal behavioral patterns associated with emotion expression in the body and face during walking. Motion capture data were collected from 42 individuals walking while ...
Genetic Modifiers of Hemostasis.
(2009)
Factor V serves as the nonenzymatic cofactor for Factor Xa to produce thrombin. A Factor V variant called Factor V Leiden (FVL) is the most common known inherited risk factor for venous thrombosis, though incomplete ...
The Effects of p53 and p53R2 Expression on Gemcitabine-Mediated Cytotoxicity and Radiosensitization.
(2009)
Gemcitabine (dFdCyd) is a nucleoside analog that produces synergistic killing of tumor cells with ionizing radiation (radiosensitization). Previously, radiosensitization correlated with dATP depletion, mediated by dFdCyd ...
Cell Specific Regulation of Sonic Hedgehog in Adult Stomach: Understanding Mechanisms Leading to Gastric Atrophy/Metaplasia. Mechanisms Leading to Gastric Atrophy/Metaplasia.
(2009)
Helicobacter induced gastritis of the corpus results in loss of parietal cell function, loss of the oxyntic gland (atrophy), changes that predispose to gastric cancer. The molecular details of how chronic inflammation in ...
Positive Emotions and Sexual Desire among Healthy Women.
(2009)
Sexual desire disorders are highly prevalent, account for a significant proportion of sexual problems, and affect important aspects of women’s lives. Sexuality research has traditionally focused on dysfunction models, ...
Bioinformatic Analysis of Epithelial:Mesenchymal Crosstalk during Mouse Gut Development and Patterning
(2009)
ABSTRACT
BIOINFORMATIC ANALYSIS OF EPITHELIAL:MESENCHYMAL CROSSTALK DURING MOUSE GUT DEVELOPMENT AND PATTERNING
By
Xing Li
Chair: Deborah L. Gumucio
The small intestine develops from a tube of endoderm wrapped by ...